Condensed Consolidated Statements of Operations (Unaudited) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2023	Jun. 30, 2022
Revenues
Type of Revenue [Extensible List]	us-gaap:ProductMember	us-gaap:ProductMember	us-gaap:ProductMember	us-gaap:ProductMember
Total revenues	$ 165,235	$ 134,563	$ 283,697	$ 250,031
Operating expenses
Type of Cost, Good or Service [Extensible List]	us-gaap:ProductMember	us-gaap:ProductMember	us-gaap:ProductMember	us-gaap:ProductMember
Cost of product sales	$ 7,459	$ 2,667	$ 9,126	$ 5,617
Research and development	58,771	75,646	127,915	204,501
Selling, general and administrative	95,968	89,901	197,203	186,580
Total operating expenses	162,198	168,214	334,244	396,698
Income (loss) from operations	3,037	(33,651)	(50,547)	(146,667)
Interest income, net	4,550	580	8,350	685
Other (loss) income	(1,244)	(497)	3,601	(157)
Income (loss) before income taxes	6,343	(33,568)	(38,596)	(146,139)
Income tax (benefit) expense	5,229	443	3,311	928
Net income (loss)	$ 1,114	$ (34,011)	$ (41,907)	$ (147,067)
Basic	$ 0.01	$ (0.21)	$ (0.26)	$ (0.91)
Diluted	$ 0.01	$ (0.21)	$ (0.26)	$ (0.91)
Basic	163,458	161,654	163,109	161,443
Diluted	165,046	161,654	163,109	161,443