Condensed Consolidated Statements of Stockholders' Equity (Unaudited) - USD ($) $ in Thousands	Total	Common Stock	Additional Paid-in Capital	Accumulated Deficit	Other Comprehensive Income (Loss)
Beginning balance at Dec. 31, 2020	$ 627,009	$ 16	$ 2,612,663	$ (1,985,706)	$ 36
Issuance of common stock from exercise of stock options and units			8,994
Issuance of common stock pursuant to employee stock purchase plan			3,737
Stock-based compensation			35,415
Net loss	(110,319)			(110,319)
Other comprehensive (loss) income					2
Ending balance at Jun. 30, 2021	564,838	16	2,660,809	(2,096,025)	38
Beginning balance at Mar. 31, 2021	581,606	16	2,633,710	(2,052,154)	34
Issuance of common stock from exercise of stock options and units			1,268
Issuance of common stock pursuant to employee stock purchase plan			3,737
Stock-based compensation			22,094
Net loss	(43,871)			(43,871)
Other comprehensive (loss) income					4
Ending balance at Jun. 30, 2021	564,838	16	2,660,809	(2,096,025)	38
Beginning balance at Dec. 31, 2021	540,894	16	2,694,646	(2,153,576)	(192)
Issuance of common stock from exercise of stock options and units			3,273
Issuance of common stock pursuant to employee stock purchase plan			3,025
Stock-based compensation			35,374
Net loss	(147,067)			(147,067)
Other comprehensive (loss) income					(651)
Ending balance at Jun. 30, 2022	434,848	16	2,736,318	(2,300,643)	(843)
Beginning balance at Mar. 31, 2022	444,797	16	2,712,025	(2,266,632)	(612)
Issuance of common stock from exercise of stock options and units			806
Issuance of common stock pursuant to employee stock purchase plan			3,025
Stock-based compensation			20,462
Net loss	(34,011)			(34,011)
Other comprehensive (loss) income					(231)
Ending balance at Jun. 30, 2022	$ 434,848	$ 16	$ 2,736,318	$ (2,300,643)	$ (843)