Selected Quarterly Financial Data (Unaudited) - Selected Quarterly Financial Data (Detail) - USD ($) $ / shares in Units, $ in Thousands		3 Months Ended																12 Months Ended
		Dec. 31, 2021		Sep. 30, 2021		Jun. 30, 2021		Mar. 31, 2021		Dec. 30, 2020		Sep. 30, 2020		Jun. 30, 2020		Mar. 31, 2020		Dec. 31, 2021		Dec. 31, 2020		Dec. 31, 2019
Quarterly Financial Information Disclosure [Abstract]
Revenues		$ 130,758		$ 131,612		$ 115,221		$ 106,554		$ 121,007		$ 120,577		$ 110,103		$ 90,068		$ 484,145		$ 441,755
Gross profit	[1]	128,314		127,924		112,695		104,369		118,499		118,572		107,204		87,269		473,302		431,544
Net loss		$ (43,094)		$ (14,457)		$ (43,871)		$ (66,448)		$ (66,760)		$ (84,660)		$ (42,141)		$ (88,023)		$ (167,870)		$ (281,584)		$ (235,259)
Basic and diluted net loss per share		$ (0.27)	[2]	$ (0.09)	[2]	$ (0.27)	[2]	$ (0.42)	[2]	$ (0.42)	[2]	$ (0.05)	[2]	$ (0.27)	[2]	$ (0.57)	[2]	$ (1.05)	[2]	$ (1.79)	[2]	$ (1.60)

[1] Determined by subtracting cost of product sales from product sales, net.

[2] Net loss per common share, basic and diluted, are computed independently for each quarter and the full year based upon respective average shares outstanding. Therefore, the sum of the quarterly net loss per common share amounts may not equal the annual amounts reported.