XML 19 R4.htm IDEA: XBRL DOCUMENT v3.24.0.1
Consolidated Statements of Operations - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Revenues:      
Revenue $ 937,822 $ 698,801 $ 538,593
Operating expenses:      
Cost of product sales, excluding amortization of acquired intangible assets 65,486 44,678 32,328
Amortization of intangible assets 222,635 116,554 54,751
Research and development 666,563 651,496 540,684
Selling, general and administrative 332,540 325,998 285,773
Change in the fair value of contingent consideration (127,700) (25,900) (500)
Intangible asset impairment 217,800 33,384  
Total operating expenses 1,377,324 1,146,210 913,036
Loss from operations (439,502) (447,409) (374,443)
Interest expense, net (129,180) (90,871) (86,022)
Other income (expense), net 10,130 (49,207) (57,875)
Loss on extinguishment of debt (137,558)    
Loss before income tax benefit (expense) (696,110) (587,487) (518,340)
Income tax benefit (expense) 69,506 28,470 (5,561)
Net loss attributable to common stockholders $ (626,604) $ (559,017) $ (523,901)
Weighted-average shares outstanding:      
Basic 74,838,392 71,728,634 70,466,393
Diluted 74,838,392 71,728,634 70,466,393
Net loss per share-basic and diluted (in dollars per share)      
Basic $ (8.37) $ (7.79) $ (7.43)
Diluted $ (8.37) $ (7.79) $ (7.43)
Net product revenue      
Revenues:      
Revenue $ 661,249 $ 535,228 $ 428,904
Collaboration revenue      
Revenues:      
Revenue 100,030 50,052 55,046
Royalty revenue      
Revenues:      
Revenue 168,856 113,521 54,643
Manufacturing revenue      
Revenues:      
Revenue $ 7,687 $ 0 $ 0