Accounts payable and accrued expenses (Details) - USD ($) $ in Thousands |
Sep. 30, 2018 |
Dec. 31, 2017 |
|---|---|---|
| Payables and Accruals [Abstract] | ||
| Employee compensation, benefits, and related accruals | $ 18,003 | $ 17,711 |
| Consulting and contracted research | 8,111 | 5,137 |
| Professional fees | 3,541 | 2,116 |
| Sales allowance and other costs | 27,027 | 22,257 |
| Sales rebates and royalties | 26,818 | 11,657 |
| Accounts payable | 6,538 | 15,282 |
| Other | 12,750 | 2,286 |
| Accounts payable and accrued expenses | $ 102,788 | $ 76,446 |
| X | ||||||||||
- Definition Represents the carrying value as of the balance sheet date of obligations incurred through that date and payable for consulting and contracted research. No definition available.
|
| X | ||||||||||
- Definition Sales Allowance And Other Related Costs No definition available.
|
| X | ||||||||||
- Definition Sales Rebates And Royalties, Current No definition available.
|
| X | ||||||||||
- Definition Sum of the carrying values as of the balance sheet date of obligations incurred through that date and due within one year (or the operating cycle, if longer), including liabilities incurred (and for which invoices have typically been received) and payable to vendors for goods and services received, taxes, interest, rent and utilities, accrued salaries and bonuses, payroll taxes and fringe benefits. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
|
| X | ||||||||||
- Definition Carrying value as of the balance sheet date of liabilities incurred (and for which invoices have typically been received) and payable to vendors for goods and services received that are used in an entity's business. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
|
| X | ||||||||||
- Definition Carrying value as of the balance sheet date of obligations incurred through that date and payable for professional fees, such as for legal and accounting services received. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
|
| X | ||||||||||
- Definition Total of the carrying values as of the balance sheet date of obligations incurred through that date and payable for obligations related to services received from employees, such as accrued salaries and bonuses, payroll taxes and fringe benefits. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
|
| X | ||||||||||
- Definition Amount of expenses incurred but not yet paid classified as other, due within one year or the normal operating cycle, if longer. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
|
| X | ||||||||||
- References No definition available.
|