Selected quarterly financial data (Details) (USD $) In Thousands, except Per Share data, unless otherwise specified
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1 Months Ended |
3 Months Ended |
12 Months Ended |
Jul. 31, 2012
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Dec. 31, 2014
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Sep. 30, 2014
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Jun. 30, 2014
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Mar. 31, 2014
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Dec. 31, 2013
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Sep. 30, 2013
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Jun. 30, 2013
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Mar. 31, 2013
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Dec. 31, 2014
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Dec. 31, 2013
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Dec. 31, 2012
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Selected quarterly financial data |
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Net Product Sales |
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$ 636ptct_NetProductSales |
$ 81ptct_NetProductSales |
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$ 717ptct_NetProductSales |
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Collaboration and grant revenue |
|
12,022ptct_CollaborationAndGrantRevenue |
1,613ptct_CollaborationAndGrantRevenue |
1,677ptct_CollaborationAndGrantRevenue |
9,217ptct_CollaborationAndGrantRevenue |
4,411ptct_CollaborationAndGrantRevenue |
16,290ptct_CollaborationAndGrantRevenue |
6,854ptct_CollaborationAndGrantRevenue |
7,142ptct_CollaborationAndGrantRevenue |
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Operating Expenses |
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44,888us-gaap_OperatingExpenses |
29,295us-gaap_OperatingExpenses |
27,046us-gaap_OperatingExpenses |
23,429us-gaap_OperatingExpenses |
22,503us-gaap_OperatingExpenses |
20,565us-gaap_OperatingExpenses |
21,307us-gaap_OperatingExpenses |
15,718us-gaap_OperatingExpenses |
124,658us-gaap_OperatingExpenses |
80,094us-gaap_OperatingExpenses |
60,754us-gaap_OperatingExpenses |
Loss from operations |
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(32,230)us-gaap_OperatingIncomeLoss |
(27,601)us-gaap_OperatingIncomeLoss |
(25,369)us-gaap_OperatingIncomeLoss |
(14,212)us-gaap_OperatingIncomeLoss |
(18,093)us-gaap_OperatingIncomeLoss |
(4,276)us-gaap_OperatingIncomeLoss |
(14,453)us-gaap_OperatingIncomeLoss |
(8,576)us-gaap_OperatingIncomeLoss |
(99,413)us-gaap_OperatingIncomeLoss |
(45,398)us-gaap_OperatingIncomeLoss |
(26,808)us-gaap_OperatingIncomeLoss |
Net loss |
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(17,886)us-gaap_NetIncomeLoss |
(4,416)us-gaap_NetIncomeLoss |
(14,587)us-gaap_NetIncomeLoss |
(14,685)us-gaap_NetIncomeLoss |
(93,753)us-gaap_NetIncomeLoss |
(51,574)us-gaap_NetIncomeLoss |
(26,235)us-gaap_NetIncomeLoss |
Deemed Dividend |
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18,249ptct_DeemedDividend |
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18,249ptct_DeemedDividend |
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Gain on exchange of convertible preferred stock in connection with recapitalization |
160,000us-gaap_PreferredStockRedemptionDiscount |
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3,391us-gaap_PreferredStockRedemptionDiscount |
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3,391us-gaap_PreferredStockRedemptionDiscount |
159,954us-gaap_PreferredStockRedemptionDiscount |
Less beneficial conversion charge |
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(378)us-gaap_PreferredStockConversionsInducements |
Net income (loss) attributable to common stockholders |
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$ (27,269)us-gaap_ProfitLoss |
$ (27,282)us-gaap_ProfitLoss |
$ (25,104)us-gaap_ProfitLoss |
$ (14,098)us-gaap_ProfitLoss |
$ (17,886)us-gaap_ProfitLoss |
$ (4,416)us-gaap_ProfitLoss |
$ (14,587)us-gaap_ProfitLoss |
$ (29,543)us-gaap_ProfitLoss |
$ (93,753)us-gaap_ProfitLoss |
$ (66,432)us-gaap_ProfitLoss |
$ 133,341us-gaap_ProfitLoss |
Basic net income (loss) per common share |
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$ (0.84)us-gaap_EarningsPerShareBasic |
$ (0.93)us-gaap_EarningsPerShareBasic |
$ (0.86)us-gaap_EarningsPerShareBasic |
$ (0.58)us-gaap_EarningsPerShareBasic |
$ (0.75)us-gaap_EarningsPerShareBasic |
$ (0.19)us-gaap_EarningsPerShareBasic |
$ (5.51)us-gaap_EarningsPerShareBasic |
$ (6,527.30)us-gaap_EarningsPerShareBasic |
$ (2.97)us-gaap_EarningsPerShareBasic |
$ (5.18)us-gaap_EarningsPerShareBasic |
$ 219.76us-gaap_EarningsPerShareBasic |
Diluted net income (loss) per common share |
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$ (0.84)us-gaap_EarningsPerShareDiluted |
$ (0.93)us-gaap_EarningsPerShareDiluted |
$ (0.86)us-gaap_EarningsPerShareDiluted |
$ (0.58)us-gaap_EarningsPerShareDiluted |
$ (0.75)us-gaap_EarningsPerShareDiluted |
$ (0.19)us-gaap_EarningsPerShareDiluted |
$ (5.51)us-gaap_EarningsPerShareDiluted |
$ (6,527.30)us-gaap_EarningsPerShareDiluted |
$ (2.97)us-gaap_EarningsPerShareDiluted |
$ (5.18)us-gaap_EarningsPerShareDiluted |
$ 42.50us-gaap_EarningsPerShareDiluted |