UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549
                                ----------------

                                  SCHEDULE 14A

                Proxy Statement Pursuant to Section 14(a) of the
                       Securities and Exchange Act of 1934



Filed by the Registrant [X]
Filed by a Party other than the Registrant [ ]

Check the appropriate box:
[ ]   Preliminary Proxy Statement
[ ]   Confidential, for Use of the Commission Only (as permitted by Rule
      14a-6(e)(2))
[ ]   Definitive Proxy Statement
[X]   Definitive Additional Materials
[ ]   Soliciting Material Under Rule 14a-12


                          MISSION WEST PROPERTIES, INC.
                (Name of Registrant as Specified In Its Charter)

             -------------------------------------------------------
      (Name of Person(s) Filing Proxy Statement, if other than Registrant)



Payment of Filing Fee (Check the appropriate box):
[X]   No fee required
[ ]   Fee computed on table below per Exchange Act Rules 14a-6(i)(1) and 0-11
      (1)  Title of each class of securities to which transaction applies:
      (2)  Aggregate number of securities to transaction applies:
      (3)  Per unit  price  or other  underlying  value of  transaction computed
           pursuant to Exchange Act Rule  0-11(set forth the amount on which the
           filing fee is calculated and state how it was determined):
      (4)  Proposed maximum aggregate value of transaction:
      (5)  Total fee paid:

[ ]   Fee paid previously with preliminary materials
[ ]   Check box if  any part  of the fee is offset  as provided by  Exchange Act
      Rule 0-11(a)(2) and identify the filing for  which the offsetting  fee was
      paid previously.  Identify the  previous filing by  registration statement
      number, or the Form or Schedule and the date of its filing.
     (1)   Amount Previously Paid:
     (2)   Form, Schedule or Registration Statement No.:
     (3)   Filing Party:
     (4)   Date Filed:






                          MISSION WEST PROPERTIES, INC.
                               ------------------
                            ------------------------

                       SOLICITED BY THE BOARD OF DIRECTORS
                    FOR THE 2008 ANNUAL STOCKHOLDERS' MEETING



     The undersigned  hereby  appoints Carl E. Berg and Raymond V. Marino,  each
with the  power  to  appoint  his  substitute,  and  hereby  authorizes  them to
represent  and to vote all shares of common  stock of Mission  West  Properties,
Inc. (the "Company") held of record by the undersigned in favor of each proposal
designated on this Proxy Card and to vote the shares of the undersigned in their
discretion  with  respect to other  matters that  properly  come before the 2008
Annual  Stockholders'  Meeting (the "Annual Meeting") to be held on May 22, 2008
and any adjournment of the Annual Meeting.


     THIS  PROXY  WHEN  PROPERLY  EXECUTED  WILL BE  VOTED  AS  DIRECTED.  IF NO
DIRECTION  IS GIVEN WITH RESPECT TO A  PARTICULAR  PROPOSAL,  THIS PROXY WILL BE
VOTED FOR EACH OF THE NOMINEES IN PROPOSAL 1 AND FOR PROPOSAL 2.

     PLEASE MARK,  DATE,  SIGN, AND RETURN THIS PROXY CARD  PROMPTLY,  USING THE
ENCLOSED ENVELOPE. NO POSTAGE REQUIRED IF MAILED IN THE UNITED STATES.




- --------------------------------------------------------------------------------
                                   DETACH HERE
[X]    Please  mark vote
       as in this example


                                                              
1. Election of Directors                                         2. Ratify the selection of Burr, Pilger & Mayer, LLP as our
   Nominees:  01 Carl E. Berg   02 William A. Hasler                independent registered public accounting firm for the
   03 Lawrence B. Helzel   04 Raymond V. Marino                     fiscal year ending December 31, 2008.
   05 Martin S. Roher                                                            FOR                 AGAINST             ABSTAIN
                                                                                 [ ]                   [ ]                  [ ]
   [ ] Vote FOR                        [ ] Vote WITHHELD
       all nominees                        from all nominees
       (except as marked)

Instructions: To withhold authority to vote for any
indicated nominee, write the number(s) of the nominee(s)
in the box provided below.

 ____________________________________________________
|                                                    |
|____________________________________________________|


                                                                    MARK HERE FOR
- ----------------------------------------------------                ADDRESS CHANGE            [ ]
                          Name                                      AND NOTE AT LEFT


- ----------------------------------------------------
                     Street Address                                 Please sign  exactly as name  appears  hereon.  Joint  owners
                                                                    should  each  sign.  Executors,   administrators,   trustees,
                                                                    guardians  or other  fiduciaries  should  give full  title as
- ----------------------------------------------------                such.  If signing for a corporation  or other entity,  please
    City               State    Country     Zip Code                sign  in  full  corporate  or  other  entity  name  by a duly
                                                                    authorized officer.

[ ]  Please check here if you plan to attend the 2008 Annual
     Stockholders' Meeting.


Signature:______________________________  Date:_____________      Signature:______________________________  Date:_____________