LETTER 1 filename1.txt Mail Stop 4561 November 18, 2005 Mr. Carl E. Berg Chief Executive Officer Mission West Properties, Inc. 10050 Bandley Drive Cupertino, CA 95014 Re: Mission West Properties, Inc. Form 10-K for Fiscal Year Ended December 31, 2004 Forms 10-Q for Fiscal Quarters Ended March 31, 2005 and June 30, 2005 File No. 0-25235 Dear Mr. Berg: We have completed our review of your Form 10-K and related filings and do not, at this time, have any further comments. Sincerely, Josh Forgione Staff Accountant