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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 Q4f5dSwbiIU3fYWfwd94BACdcFbI/dF56y5/T6APX0yv5jP8dPGmbfhWKbxOeeeu
 kX4ZB0rCtXCqGHOvhhyYTg==

<SEC-DOCUMENT>0001144204-10-009404.txt : 20100222
<SEC-HEADER>0001144204-10-009404.hdr.sgml : 20100222
<ACCEPTANCE-DATETIME>20100222215727
ACCESSION NUMBER:		0001144204-10-009404
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20100218
FILED AS OF DATE:		20100222
DATE AS OF CHANGE:		20100222

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Goldknopf Ira L
		CENTRAL INDEX KEY:			0001298870

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-24921
		FILM NUMBER:		10624135

	MAIL ADDRESS:	
		STREET 1:		42 BRUSHWOOD CT.
		CITY:			THE WOODLANDS
		STATE:			TX
		ZIP:			77380

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			POWER 3 MEDICAL PRODUCTS INC
		CENTRAL INDEX KEY:			0001063530
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH [8731]
		IRS NUMBER:				650565144
		STATE OF INCORPORATION:			NY
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		3400 RESEARCH FOREST DR
		STREET 2:		SUITE B2-3
		CITY:			THE WOODLANDS
		STATE:			TX
		ZIP:			77381
		BUSINESS PHONE:		281-466-1600

	MAIL ADDRESS:	
		STREET 1:		3400 RESEARCH FOREST DR
		STREET 2:		SUITE B2-3
		CITY:			THE WOODLANDS
		STATE:			TX
		ZIP:			77381

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	SURGICAL SAFETY PRODUCTS INC
		DATE OF NAME CHANGE:	19980924
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>v175223_ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2010-02-18</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001063530</issuerCik>
        <issuerName>POWER 3 MEDICAL PRODUCTS INC</issuerName>
        <issuerTradingSymbol>PWRM</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001298870</rptOwnerCik>
            <rptOwnerName>Goldknopf Ira L</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>3400 RESEARCH FOREST DRIVE, SUITE B2-3</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>THE WOODLANDS</rptOwnerCity>
            <rptOwnerState>TX</rptOwnerState>
            <rptOwnerZipCode>77381</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>President &amp; CSO</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock, $.001 par value</value>
            </securityTitle>
            <transactionDate>
                <value>2010-02-18</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>5</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>500000</value>
                    <footnoteId id="F1"/>
                </transactionShares>
                <transactionPricePerShare>
                    <value>30065</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>53833454</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">The proceeds from the sale of these shares were used by the reporting person to pay off certain debt obligations of Power3
 Medical Products, Inc.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/S/ Ira L. Goldknopf</signatureName>
        <signatureDate>2010-02-22</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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