EXHIBIT 20

FOURTH AMENDED AND RESTATED JOINT FILING AGREEMENT

This Fourth Amended and Restated Joint Filing Agreement (this “Agreement”) amends and restates the Third Amended and Restated Joint Filing Agreement, dated December 16, 2020, by and among Invus, L.P., Invus Advisors, L.L.C., Invus Public Equities, L.P., Invus Public Equities Advisors, LLC, Invus C.V., Ulys, L.L.C., Mr. Raymond Debbane, Artal International S.C.A., Artal International Management S.A., Artal Group S.A., Westend S.A., Stichting Administratiekantoor Westend (the “Stichting”) and Mr. Pascal Minne.

We, the signatories of this statement on Schedule 13D to which this Agreement is attached, hereby agree that such statement is, and any amendments thereto filed by any of us will be, filed on behalf of each of us and on behalf of any affiliate of Invus, L.P. that executes a joinder hereto.

INVUS, L.P.
By: INVUS ADVISORS, L.L.C., its general partner
By:	/s/ Raymond Debbane
Name:	Raymond Debbane
Title:	President
INVUS PUBLIC EQUITIES, L.P.
By: INVUS PUBLIC EQUITIES ADVISORS, LLC, its general partner
By:	/s/ Raymond Debbane
Name:	Raymond Debbane
Title:	President
INVUS ADVISORS, L.L.C.
By:	/s/ Raymond Debbane
Name:	Raymond Debbane
Title:	President
INVUS PUBLIC EQUITIES ADVISORS, LLC
By:	/s/ Raymond Debbane
Name:	Raymond Debbane
Title:	President
ARTAL TREASURY LIMITED
By:	/s/ Keith Le Poidevin
Name:	Keith Le Poidevin
Title:	Director

ARTAL INTERNATIONAL S.C.A.

By: ARTAL INTERNATIONAL MANAGEMENT S.A.,

its managing partner

By:	/s/ Anne Goffard
Name:	Anne Goffard
Title:	Managing Director

ARTAL INTERNATIONAL MANAGEMENT S.A.

By:	/s/ Anne Goffard
Name:	Anne Goffard
Title:	Managing Director
ARTAL GROUP S.A.
By:	/s/ Anne Goffard
Name:	Anne Goffard
Title:	Authorized Person

WESTEND S.A.
By:	/s/ Anne Goffard
Name:	Anne Goffard
Title:	Managing Director
STICHTING ADMINISTRATIEKANTOOR WESTEND
By:	/s/ Anne Goffard
Name:	Anne Goffard
Title:	Attorney-in-Fact for Pascal Minne, Sole Member of the Board
PASCAL MINNE
By:	/s/ Anne Goffard
Name: Anne Goffard Title: Attorney-in-Fact for Pascal Minne
INVUS PARTNERS, LLC
By: ULYS, L.L.C., its managing member
By:	/s/ Raymond Debbane
Name:	Raymond Debbane
Title:	President

ULYS, L.L.C.
By:	/s/ Raymond Debbane
Name:	Raymond Debbane
Title:	President
RAYMOND DEBBANE
By:	/s/ Raymond Debbane
Dated:	January 5, 2021