<SEC-DOCUMENT>0001127602-18-005197-index.html : 20180212
<SEC-HEADER>0001127602-18-005197.hdr.sgml : 20180212
<ACCEPTANCE-DATETIME>20180212171021
ACCESSION NUMBER:		0001127602-18-005197
CONFORMED SUBMISSION TYPE:	5
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20171231
FILED AS OF DATE:		20180212
DATE AS OF CHANGE:		20180212

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			WADE JEFFREY L
		CENTRAL INDEX KEY:			0001225767

	FILING VALUES:
		FORM TYPE:		5
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-30111
		FILM NUMBER:		18597483

	MAIL ADDRESS:	
		STREET 1:		8800 TECHNOLOGY FOREST PLACE
		CITY:			THE WOODLANDS
		STATE:			TX
		ZIP:			77381

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			LEXICON PHARMACEUTICALS, INC.
		CENTRAL INDEX KEY:			0001062822
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				760474169
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		8800 TECHNOLOGY FOREST PLACE
		CITY:			THE WOODLANDS
		STATE:			TX
		ZIP:			77381
		BUSINESS PHONE:		2818633000

	MAIL ADDRESS:	
		STREET 1:		8800 TECHNOLOGY FOREST PLACE
		CITY:			THE WOODLANDS
		STATE:			TX
		ZIP:			77381

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	LEXICON PHARMACEUTICALS, INC./DE
		DATE OF NAME CHANGE:	20070426

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	LEXICON GENETICS INC/TX
		DATE OF NAME CHANGE:	20000126
</SEC-HEADER>
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<TYPE>5
<SEQUENCE>1
<FILENAME>form5.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
Document 1 - file: form5.html

Document 1 - RAW XML: form5.xml

</DOCUMENT>
</SEC-DOCUMENT>