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Consolidated Statements of Stockholders' Equity - USD ($)
$ in Thousands
Total
Common Stock
Additional Paid-In Capital
Accumulated Deficit
Accumulated Other Comprehensive Gain (Loss)
Treasury Stock
Beginning balance (in shares) at Dec. 31, 2020   142,289,000        
Beginning balance at Dec. 31, 2020 $ 156,371 $ 142 $ 1,561,096 $ (1,400,018) $ (6) $ (4,843)
Stock-based compensation 10,577   10,577      
Issuance of common stock, net of fees (in shares)   6,177,000        
Issuance of common stock, net of fees 35,491 $ 6 35,485      
Issuance of equity-classified warrants 0          
Issuance of common stock under Equity Incentive Plans (in shares)   1,616,000        
Issuance of common stock under Equity Incentive Plans 1,593 $ 2 1,591      
Repurchase of common stock (2,675)         (2,675)
Net loss (87,758)     (87,758)    
Unrealized gain (loss) on investments (4)       (4)  
Ending balance (in shares) at Dec. 31, 2021   150,082,000        
Ending balance at Dec. 31, 2021 113,595 $ 150 1,608,749 (1,487,776) (10) (7,518)
Stock-based compensation 11,520   11,520      
Issuance of common stock, net of fees (in shares)   39,100,000        
Issuance of common stock, net of fees 94,205 $ 39 94,166      
Issuance of equity-classified warrants 1,030   1,030      
Issuance of treasury stock 0   (6,321)     6,321
Issuance of common stock under Equity Incentive Plans (in shares)   32,000        
Repurchase of common stock (864)         (864)
Net loss (101,944)     (101,944)    
Unrealized gain (loss) on investments $ (418)       (418)  
Ending balance (in shares) at Dec. 31, 2022 189,213,948 189,214,000        
Ending balance at Dec. 31, 2022 $ 117,124 $ 189 1,709,144 (1,589,720) (428) (2,061)
Stock-based compensation 14,340   14,340      
Issuance of common stock, net of fees (in shares)   55,288,000        
Issuance of common stock, net of fees 138,823 $ 55 138,768      
Issuance of equity-classified warrants 307   307      
Issuance of common stock under Equity Incentive Plans (in shares)   1,291,000        
Issuance of common stock under Equity Incentive Plans 0 $ 1 (1)      
Repurchase of common stock (824)         (824)
Net loss (177,119)     (177,119)    
Unrealized gain (loss) on investments $ 459       459  
Ending balance (in shares) at Dec. 31, 2023 245,792,668 245,793,000        
Ending balance at Dec. 31, 2023 $ 93,110 $ 245 $ 1,862,558 $ (1,766,839) $ 31 $ (2,885)