Summary of Significant Accounting Policies Accrued Liabilities (Details) - USD ($)	Mar. 31, 2023	Dec. 31, 2022
Accrued Liabilities [Line Items]
Accrued research and development services current	$ 3,937,000	$ 3,252,000
Accrued compensation and benefits current	4,348,000	7,830,000
Operating Lease, Liability, Current	(1,291,000)	(1,291,000)
Other Accrued Liabilities, Current	484,000	404,000
Accrued Liabilities	$ 10,060,000	$ 12,777,000