Consolidated Statements of Cash Flows - USD ($)	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Cash flows from operating activities:
Net loss	$ (101,944,000)	$ (87,758,000)	$ (58,574,000)
Adjustments to reconcile consolidated net loss to net cash provided by (used in) operating activities:
Depreciation and amortization	427,000	292,000	2,934,000
Stock-based compensation	11,520,000	10,577,000	13,274,000
Loss on disposal of property and equipment	3,000	49,000	(707,000)
Deferred tax benefit	0	0	0
Changes in operating assets and liabilities:
(Increase) decrease in accounts receivable	(14,000)	381,000	53,227,000
Increase in inventories	0	0	345,000
(Increase) decrease in prepaid expenses and other current assets	(316,000)	2,885,000	(1,948,000)
(Increase) decrease in other assets	656,000	661,000	424,000
Increase (decrease) in accounts payable and other liabilities	76,000	(14,158,000)	(20,969,000)
Net cash used in operating activities	(88,851,000)	(87,017,000)	(142,969,000)
Cash flows from investing activities:
Purchases of property and equipment	(1,326,000)	(1,221,000)	(87,000)
Proceeds from Sale of Productive Assets	0	0	160,385,000
Proceeds from Sale of Property, Plant, and Equipment	0	0
Purchases of investments	(133,949,000)	(34,261,000)	(58,555,000)
Maturities of investments	64,197,000	37,592,000	268,000,000
Net cash provided by investing activities	(71,078,000)	2,110,000	380,756,000
Cash flows from financing activities:
Proceeds from issuance of common stock, net of fees	94,205,000	37,084,000	69,970,000
Repurchase of common stock	(864,000)	(2,675,000)	(1,026,000)
Repayment of debt borrowings	48,868,000	(11,700,000)	(216,580,000)
Net cash provided by (used in) financing activities	142,209,000	22,709,000	(147,636,000)
Net increase (decrease) in cash and cash equivalents	(17,720,000)	(62,198,000)	90,151,000
Cash and cash equivalents at beginning of year	64,065,000	126,263,000	36,112,000
Cash and cash equivalents at end of year	46,345,000	64,065,000	126,263,000
Supplemental disclosure of cash flow information:
Cash paid for interest	2,289,000	799,000	17,353,000
Supplemental disclosure of noncash investing and financing activities:
Common stock, $.001 par value; 225,000 shares authorized; 106,679 and 106,162 shares issued, respectively	0	0	15,714,000
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Liabilities	0	0	3,437,000
Amortization of debt issuance costs	741,000	54,000	1,013,000
Gain on sale of non-financial assets	0	0	(132,585,000)
Impairment of Real Estate	0	0	1,600,000
Impairment of Intangible Assets (Excluding Goodwill)	0	0
Recognition of gain or loss on extinguishment	0	0	(1,003,000)
Proceeds from Sale of Buildings			11,013,000
Severance Costs			5,500,000
Right-of-use assets	6,800,000	2,300,000	0
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability	5,206,000
Issuance of Stock and Warrants for Services or Claims	1,030,000	0	0
Unearned ESOP Shares	6,321,000
Stock Issued During Period, Value, Treasury Stock Reissued	0	0	0
Business Exit Costs	$ 1,500,000	0	0
Extinguishment of Debt, Gain (Loss), Net of Tax			$ (1,003,000)
Right-of-Use Asset Obtained in Exchange for Finance Lease Liability		$ 1,704,000