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Summary of Significant Accounting Policies Stock-based Compensation Valuation (Details)
9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Mar. 31, 2021
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Lexicon incremental borrowing rate 970.00%   900.00%
Equity Option [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, ExpectedVolatilityRate, Employees 107.00% 102.00%  
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Employee 2.40% 0.60%  
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Term, Employees 4 years 4 years  
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Dividend Rate, Employees 0.00% 0.00%  
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Officers and Non-employee Directors 91.00% 90.00%  
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Officers and Non-employee Directors 1.90% 1.10%  
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Term, Officers and Non-employee Directors 7 years 7 years  
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Dividend Rate, Officers and Non-employee Directors 0.00% 0.00%