Summary of Significant Accounting Policies Accrued Liabilities (Details) - USD ($)	Jun. 30, 2022	Dec. 31, 2021	Mar. 01, 2021
Accrued Liabilities [Line Items]
Accrued research and development services current	$ 3,920,000	$ 3,669,000
Accrued compensation and benefits current	4,329,000	5,711,000
Operating Lease, Liability, Current	(789,000)	(1,089,000)
Other Accrued Liabilities, Current	477,000	2,503,000
Accrued Liabilities	$ 9,515,000	$ 12,972,000
Lexicon incremental borrowing rate			900.00%