Consolidated Statements of Cash Flows - USD ($)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Cash flows from operating activities:
Net loss	$ (87,758,000)	$ (58,574,000)	$ 130,133,000
Adjustments to reconcile consolidated net loss to net cash provided by (used in) operating activities:
Depreciation and amortization	292,000	2,934,000	3,654,000
Stock-based compensation	10,577,000	13,274,000	14,218,000
Loss on disposal of property and equipment	49,000	(707,000)	0
Deferred tax benefit	0	0	(6,014,000)
Changes in operating assets and liabilities:
(Increase) decrease in accounts receivable	381,000	53,227,000	(50,608,000)
Increase in inventories	0	345,000	437,000
(Increase) decrease in prepaid expenses and other current assets	2,885,000	(1,948,000)	(2,652,000)
(Increase) decrease in other assets	661,000	424,000	429,000
Increase (decrease) in accounts payable and other liabilities	(14,158,000)	(20,969,000)	20,097,000
Decrease in deferred revenue	0	0	(25,990,000)
Net cash used in operating activities	(87,017,000)	(142,969,000)	113,807,000
Cash flows from investing activities:
Purchases of property and equipment	(1,221,000)	(87,000)	(70,000)
Proceeds from Sale of Productive Assets	0	160,385,000	0
Proceeds from Sale of Property, Plant, and Equipment	0	11,013,000
Purchases of investments	(34,261,000)	(58,555,000)	(322,385,000)
Maturities of investments	37,592,000	268,000,000	166,600,000
Net cash provided by investing activities	2,110,000	380,756,000	(155,855,000)
Cash flows from financing activities:
Proceeds from issuance of common stock, net of fees	37,084,000	69,970,000	0
Repurchase of common stock	(2,675,000)	(1,026,000)	(941,000)
Repayment of debt borrowings	(11,700,000)	(216,580,000)	(1,285,000)
Net cash provided by (used in) financing activities	22,709,000	(147,636,000)	(2,226,000)
Net increase (decrease) in cash and cash equivalents	(62,198,000)	90,151,000	(44,274,000)
Cash and cash equivalents at beginning of year	126,263,000	36,112,000	80,386,000
Cash and cash equivalents at end of year	64,065,000	126,263,000	36,112,000
Supplemental disclosure of cash flow information:
Cash paid for interest	799,000	17,353,000	19,211,000
Supplemental disclosure of noncash investing and financing activities:
Common stock, $.001 par value; 225,000 shares authorized; 106,679 and 106,162 shares issued, respectively	0	15,714,000	0
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Liabilities	0	3,437,000	0
Amortization of debt issuance costs	54,000	1,013,000	1,465,000
Gain on sale of non-financial assets	0	(132,585,000)	0
Impairment of Real Estate	0	1,600,000	0
Impairment of Intangible Assets (Excluding Goodwill)	0	0	0
Asset Impairment Charges	0	1,600,000	28,638,000
Recognition of gain or loss on extinguishment	0	(1,003,000)	0
Proceeds from Sale of Buildings		11,900,000	0
Severance Costs		5,500,000
Right-of-use assets	2,300,000	$ 0	$ 1,799,000
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability	$ 1,704,000