Summary of Significant Accounting Policies - Property and Equipment (Details) - USD ($) $ in Thousands	1 Months Ended	12 Months Ended
	Aug. 31, 2018	Dec. 31, 2021	Dec. 31, 2020
Property, Plant and Equipment [Line Items]
Estimated useful life of assets	10 years
Accrued research and development services current		$ 3,669	$ 21,962
Accrued compensation and benefits current		5,711	6,200
Operating Lease, Liability, Current		1,089	553
Other Accrued Liabilities, Current		2,503	976
Accrued Liabilities		$ 12,972	$ 29,691
Minimum
Property, Plant and Equipment [Line Items]
Estimated useful life of assets		3 years
Maximum
Property, Plant and Equipment [Line Items]
Estimated useful life of assets		40 years