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Earnings Per Share
12 Months Ended
Dec. 31, 2021
Earnings Per Share [Abstract]  
Earnings Per Share Earnings (Loss) Per ShareThe following is a summary of Lexicon’s earnings (loss) per share calculations and reconciliations of the numerators and the denominators of the basic and diluted per share calculations.
Year Ended December 31,
(In thousands, except per share amounts)202120202019
Numerator:
Net income (loss)$(87,758)$(58,574)$130,133 
  Add interest expense on Convertible Notes— — 5,067 
Adjusted net income (loss)$(87,758)$(58,574)$135,200 
Denominator:
Shares used in computing net income (loss) per common share, basic145,652 110,841 106,218 
Add effect of potential dilutive securities
  Share based awards— — 164 
  Convertible Notes— — 10,365 
Shares used in computing net income (loss) per common share, diluted145,652 110,841 116,747 
Net income (loss) per share - basic$(0.60)$(0.53)$1.23 
Net income (loss) per share - diluted$(0.60)$(0.53)$1.16 


For periods presented with a net loss, the weighted average number of shares outstanding are the same for both basic and diluted net loss per common share. The average number of shares associated with stock options and restricted stock units that were excluded from diluted earnings per share that would potentially dilute earnings per share in the future was 10,221,278, 11,113,054 and 8,206,390, respectively, for the years ended December 31, 2021, 2020 and 2019. Prior to the extinguishment of the Convertible Notes, for periods presented with a net loss, the shares associated with the Convertible Notes are not included in the computation of diluted earnings per share because they are antidilutive.