Consolidated Statements of Comprehensive Loss-Unaudited - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2021	Mar. 31, 2020
Revenues:
Net product revenue	$ 0	$ 7,877
Collaborative agreements	0	8
Royalties and other revenue	27	114
Total revenues	27	7,999
Operating expenses:
Cost of sales (including finite-lived intangible asset amortization)	0	568
Research and development, including stock-based compensation of $1,286 and $2,176, respectively	12,609	55,181
Selling, general and administrative, including stock-based compensation of $1,565, and $2,256, respectively	8,257	14,688
Total operating expenses	20,866	70,437
Loss from operations	(20,839)	(62,438)
Interest expense	(167)	(5,131)
Interest and other income, net	48	958
Net loss	$ (20,958)	$ (66,611)
Net income (loss) per common share, Basic	$ (0.15)	$ (0.63)
Shares used in computing net loss per common share, Basic	143,379	106,536
Unrealized gain on investments	$ 11	$ 776
Comprehensive loss	(20,947)	(65,835)
Stock-based compensation expense associated with research and development expense	1,286	2,176
Stock-based compensation expense associated with selling, general and administrative expense	$ 1,565	$ 2,256