Summary of Significant Accounting Policies Accrued Liabilities (Details) - USD ($)	Mar. 31, 2021	Mar. 01, 2021	Dec. 31, 2020
Accrued Liabilities [Line Items]
Accrued research and development services current	$ 16,505,000		$ 21,962,000
Accrued compensation and benefits current	3,552,000		6,200,000
Operating Lease, Liability, Current	1,026,000		(553,000)
Other Accrued Liabilities, Current	1,326,000		976,000
Accrued Liabilities	$ 22,409,000		$ 29,691,000
Lexicon incremental borrowing rate		900.00%