Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2017	Sep. 30, 2016
Cash flows from operating activities:
Net loss	$ (100,672)	$ (109,010)
Adjustments to reconcile consolidated net loss to net cash used in operating activities:
Depreciation and amortization	2,475	1,548
Increase (decrease) in fair value of Symphony Icon, Inc. purchase liability	2,101	(703)
Stock-based compensation	7,214	5,722
Amortization of debt issuance costs	412	389
Deferred tax benefit	(8,652)	0
Loss on disposal of property and equipment	2	12
Changes in operating assets and liabilities:
(Increase) decrease in accounts receivable	(3,105)	173
(Increase) in inventory	(2,149)	0
(Increase) decrease in prepaid expenses and other current assets	(580)	7,694
(Increase) decrease in other assets	32	(25)
Increase (decrease) in accounts payable and other liabilities	(11,738)	18,705
Decrease in deferred revenue	(37,023)	(51,342)
Net cash used in operating activities	(151,683)	(126,837)
Cash flows from investing activities:
Purchases of property and equipment	(224)	(83)
Purchases of investments	(59,237)	(336,649)
Maturities of investments	245,749	298,525
Net cash provided by (used in) investing activities	186,288	(38,207)
Cash flows from financing activities:
Proceeds from issuance of common stock	5,481	2,943
Repurchase of common stock	(1,679)	(621)
Repayment of debt borrowings	(1,714)	(1,495)
Net cash provided by financing activities	2,088	827
Net increase (decrease) in cash and cash equivalents	36,693	(164,217)
Cash and cash equivalents at beginning of period	46,600	202,989
Cash and cash equivalents at end of period	83,293	38,772
Supplemental disclosure of cash flow information:
Cash paid for interest	3,272	3,406
Supplemental disclosure of non-cash investing and financing activities:
Common stock issued in satisfaction of Symphony Icon payment obligation	10,499	0
Unrealized gain on investments	$ 132	$ 297