Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2017	Jun. 30, 2016
Cash flows from operating activities:
Net loss	$ (69,950)	$ (72,995)
Adjustments to reconcile consolidated net loss to net cash used in operating activities:
Depreciation and amortization	1,552	1,037
Increase in fair value of Symphony Icon, Inc. purchase liability	2,101	1,443
Stock-based compensation	4,634	3,792
Amortization of debt issuance costs	254	250
Deferred tax benefit	(8,652)	0
Loss on disposal of property and equipment	2	12
Changes in operating assets and liabilities:
(Increase) decrease in accounts receivable	2,478	(107)
(Increase) in inventory	(811)	0
Increase in prepaid expenses and other current assets	(6,296)	1,066
Decrease in other assets	33	0
Increase (decrease) in accounts payable and other liabilities	(22,269)	5,818
Decrease in deferred revenue	(20,797)	(31,934)
Net cash used in operating activities	(117,721)	(91,618)
Cash flows from investing activities:
Purchases of property and equipment	(163)	(67)
Purchases of investments	(59,989)	(219,437)
Maturities of investments	159,393	147,400
Net cash provided by (used in) investing activities	99,241	(72,104)
Cash flows from financing activities:
Proceeds from issuance of common stock	5,427	752
Repurchase of common stock	(1,679)	(621)
Repayment of debt borrowings	(1,162)	(988)
Net cash provided by (used in) financing activities	2,586	(857)
Net decrease in cash and cash equivalents	(15,894)	(164,579)
Cash and cash equivalents at beginning of period	46,600	202,989
Cash and cash equivalents at end of period	30,706	38,410
Supplemental disclosure of cash flow information:
Cash paid for interest	2,956	3,046
Supplemental disclosure of non-cash investing and financing activities:
Common stock issued in satisfaction of Symphony Icon payment obligation	10,499	0
Unrealized gain (loss) on investments	$ (19)	$ 555