Consolidated Statements of Stockholders' Equity - USD ($) shares in Thousands, $ in Thousands	Total	Common Stock	Additional Paid-In Capital	Accumulated Deficit	Accumulated Other Comprehensive Gain (Loss)	Treasury Stock
Balance, shares at Dec. 31, 2013		73,478
Balance, value at Dec. 31, 2013	$ 170,163	$ 73	$ 1,175,549	$ (1,003,958)	$ 2	$ (1,503)
Stock-based compensation	7,081	$ 0	7,081	0	0	0
Issuance of common stock to designees of Symphony Icon Holdings LLC, shares		666
Issuance of common stock to designees of Symphony Icon Holdings LLC, value	5,750	$ 1	5,749	0	0	0
Issuance of common stock under Equity Incentive Plans, shares		252
Issuance of common stock under Equity Incentive Plans, value	323	$ 1	322	0	0	0
Issuance of common stock, net of fees, shares		29,267
Issuance of common stock, net of fees, value	201,947	$ 29	201,918	0	0	0
Repurchase of common stock	(887)	0	0	0	0	(887)
Net loss	(100,294)	0	0	(100,294)	0	0
Unrealized gain (loss) on investments	(65)	$ 0	0	0	(65)	0
Balance, shares at Dec. 31, 2014		103,663
Balance, value at Dec. 31, 2014	284,018	$ 104	1,390,619	(1,104,252)	(63)	(2,390)
Stock-based compensation	6,843	$ 0	6,843	0	0	0
Issuance of common stock to designees of Symphony Icon Holdings LLC, value	0
Issuance of common stock under Equity Incentive Plans, shares		197
Issuance of common stock under Equity Incentive Plans, value	114	$ 0	114	0	0	0
Repurchase of common stock	(357)	0	0	0	0	(357)
Net loss	(4,682)	0	0	(4,682)	0	0
Unrealized gain (loss) on investments	(156)	$ 0	0	0	(156)	0
Balance, shares at Dec. 31, 2015		103,860
Other	70	$ 0	70	0	0	0
Balance, value at Dec. 31, 2015	285,850	104	1,397,646	(1,108,934)	(219)	(2,747)
Stock-based compensation	7,452	$ 0	7,452	0	0	0
Issuance of common stock to designees of Symphony Icon Holdings LLC, value	0
Issuance of common stock under Equity Incentive Plans, shares		722
Issuance of common stock under Equity Incentive Plans, value	6,125	$ 1	6,124	0	0	0
Repurchase of common stock	(621)	0	0	0	0	(621)
Net loss	(141,429)	0	0	(141,429)	0	0
Unrealized gain (loss) on investments	24	$ 0	0	0	24	0
Balance, shares at Dec. 31, 2016		104,582
Balance, value at Dec. 31, 2016	$ 157,401	$ 105	$ 1,411,222	$ (1,250,363)	$ (195)	$ (3,368)