Equity Incentive Awards

Equity Incentive Plans

Equity Incentive Plan: In September 1995, Lexicon adopted the 1995 Stock Option Plan, which was subsequently amended and restated in February 2000, April 2009, April 2012 and April 2015 and renamed the Equity Incentive Plan (the “Equity Incentive Plan”).

The Equity Incentive Plan provides for the grant of incentive stock options to employees and nonstatutory stock options to employees, directors and consultants of the Company. The plan also permits the grant of stock bonus awards, restricted stock awards, restricted stock unit (phantom stock) awards and stock appreciation rights. Incentive and nonstatutory stock options have an exercise price of 100% or more of the fair market value of our common stock on the date of grant. The purchase price of restricted stock awards may not be less than 85% of fair market value. However, the plan administrator may award stock bonus awards in consideration of past services or phantom stock awards without a purchase payment. Shares may be subject to a repurchase option in the discretion of the plan administrator. Most options granted under the Equity Incentive Plan become vested and exercisable over a period of four years; however some have been granted with different vesting schedules. Options granted under the Equity Incentive Plan have a term of ten years from the date of grant.

The total number of shares of common stock that may be issued pursuant to stock awards under the Equity Incentive Plan shall not exceed in the aggregate 10,000,000 shares. No more than 3,571,428 shares may be issued pursuant to awards other than stock options and stock appreciation rights. As of December 31, 2016, an aggregate of 10,000,000 shares of common stock had been reserved for issuance, options to purchase 4,646,796 shares and 874,527 restricted stock units were outstanding, 1,354,248 shares had been issued upon the exercise of stock options, 832,642 shares had been issued pursuant to restricted stock units and 113,940 shares had been issued pursuant to stock bonus awards or restricted stock awards granted under the Equity Incentive Plan.

Non-Employee Directors’ Equity Incentive Plan: In February 2000, Lexicon adopted the 2000 Non-Employee Directors’ Stock Option Plan, which was subsequently amended and restated in April 2009, April 2012 and April 2015 and renamed the Non-Employee Directors’ Equity Incentive Plan (the “Directors’ Plan”). Under the Directors’ Plan, non-employee directors receive an initial option to purchase 4,285 shares of common stock. In addition, on the day following each of the Company’s annual meetings of stockholders, each non-employee director who has been a director for at least six months is automatically granted an option to purchase 2,857 shares of common stock and a restricted stock award of the number of shares of common stock having a fair market value on the date of grant of $20,000, rounded down to the nearest whole share number. Initial option grants become vested and exercisable over a period of five years and annual option grants become vested over a period of 12 months from the date of grant. Options granted under the Directors’ Plan have an exercise price equal to the fair market value of the Company’s common stock on the date of grant and a term of ten years from the date of grant.

The total number of shares of common stock that may be issued pursuant to stock awards under the Directors’ Plan shall not exceed in the aggregate 357,142 shares. As of December 31, 2016, an aggregate of 357,142 shares of common stock had been reserved for issuance, options to purchase 187,115 shares were outstanding, none had been issued upon the exercise of stock options and 72,448 shares had been issued pursuant to restricted stock awards granted under the Directors’ Plan.

Stock Option Activity: The following is a summary of option activity under Lexicon’s equity incentive plans:



	2016				2015				2014
(in thousands, except exercise price data)	Options		Weighted Average Exercise Price		Options		Weighted Average Exercise Price		Options		Weighted Average Exercise Price
Outstanding at beginning of year	4,217		$	12.35	3,371		$	14.98	3,329		$	16.94
Granted	1,370		10.40		1,207		6.83		643		11.76
Exercised	(495	)	12.17		(19	)	11.14		(32	)	10.22
Expired	(195	)	27.33		(187	)	27.29		(476	)	24.78
Forfeited	(63	)	10.45		(155	)	8.51		(93	)	13.79
Outstanding at end of year	4,834		11.24		4,217		12.35		3,371		14.98
Exercisable at end of year	2,727		$	12.55	2,686		$	14.53	2,417		$	15.89

The weighted average estimated grant date fair value of options granted during the years ended December 31, 2016, 2015 and 2014 were $6.43, $4.58 and $8.61, respectively. The total intrinsic value of options exercised during the years ended December 31, 2016, 2015 and 2014 were $1.7 million, $35,000 and $43,000, respectively. The weighted average remaining contractual term of options outstanding and exercisable was 6.5 and 4.8 years, respectively, as of December 31, 2016. At December 31, 2016, the aggregate intrinsic value of the outstanding options and the exercisable options was $15.6 million and $6.0 million, respectively.

Stock Bonus and Restricted Stock Unit Activity:

During the years ended December 31, 2016, 2015 and 2014, Lexicon granted its non-employee directors 11,456, 21,360 and 14,651 shares, respectively, of restricted stock awards. The restricted stock awards had weighted average grant date fair values of $13.96, $7.49 and $10.92 per share, respectively, and vested immediately. During the year ended December 31, 2014, Lexicon granted a consultant 8,200 shares of restricted stock awards. The restricted stock awards had a weighted average grant date fair value of $11.20 per share and vested immediately.

During the years ended December 31, 2016, 2015 and 2014, Lexicon granted its employees restricted stock units in lieu of or in addition to annual stock option awards. These restricted stock units vest in four annual installments. The following is a summary of restricted stock units activity under Lexicon’s stock-based compensation plans for the year ended December 31, 2016:



	Shares		Weighted Average Grant Date Fair Value
	(in thousands)
Outstanding at December 31, 2015	637		$	8.74
Granted	496		8.20
Vested	(206	)	9.75
Forfeited	(52	)	9.82
Outstanding at December 31, 2016	875		$	8.13

Aggregate Shares Reserved for Issuance

As of December 31, 2016, an aggregate of 5,708,438 shares of common stock were reserved for issuance upon exercise of outstanding stock options and vesting of outstanding restricted stock units and 2,275,426 additional shares were available for future grants under Lexicon’s equity incentive plans. The Company has a policy of using either authorized and unissued shares or treasury shares, including shares acquired by purchase in the open market or in private transactions, to satisfy equity award exercises.