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Summary of Significant Accounting Policies Segment Information and Signficant Customers (Details)
12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Revenue, Major Customer      
Entity Wide Revenue Sanofi Percentage 98.00%    
Entity Wide Revenue Ipsen Percentage   94.00%  
Entity-Wide Revenue, McNair Medical Institute, Percentage     57.00%
Entity-Wide Revenue, Taconic Farms, Percentage     33.00%