<SEC-DOCUMENT>0001062822-16-000042-index.html : 20160122
<SEC-HEADER>0001062822-16-000042.hdr.sgml : 20160122
<ACCEPTANCE-DATETIME>20160122161146
ACCESSION NUMBER:		0001062822-16-000042
CONFORMED SUBMISSION TYPE:	8-K
PUBLIC DOCUMENT COUNT:		20
CONFORMED PERIOD OF REPORT:	20160121
ITEM INFORMATION:		Entry into a Material Definitive Agreement
ITEM INFORMATION:		Financial Statements and Exhibits
FILED AS OF DATE:		20160122
DATE AS OF CHANGE:		20160122

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			LEXICON PHARMACEUTICALS, INC.
		CENTRAL INDEX KEY:			0001062822
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				760474169
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		8-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-30111
		FILM NUMBER:		161356349

	BUSINESS ADDRESS:	
		STREET 1:		8800 TECHNOLOGY FOREST PLACE
		CITY:			THE WOODLANDS
		STATE:			TX
		ZIP:			77381
		BUSINESS PHONE:		2818633000

	MAIL ADDRESS:	
		STREET 1:		8800 TECHNOLOGY FOREST PLACE
		CITY:			THE WOODLANDS
		STATE:			TX
		ZIP:			77381

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	LEXICON PHARMACEUTICALS, INC./DE
		DATE OF NAME CHANGE:	20070426

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	LEXICON GENETICS INC/TX
		DATE OF NAME CHANGE:	20000126
</SEC-HEADER>
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<TYPE>8-K
<SEQUENCE>1
<FILENAME>form8-k01x22x2016.htm
<DESCRIPTION>8-K
<TEXT>
Document 1 - file: form8-k01x22x2016.htm

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<DOCUMENT>
<TYPE>EX-10.1
<SEQUENCE>2
<FILENAME>exh101realestatepurchasean.htm
<DESCRIPTION>EXHIBIT 10.1
<TEXT>
Document 2 - file: exh101realestatepurchasean.htm

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<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>g1a02.jpg
<TEXT>
Document 3 - file: g1a02.jpg

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<SEQUENCE>4
<FILENAME>g2.jpg
<TEXT>
Document 4 - file: g2.jpg

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<TEXT>
Document 5 - file: g3.jpg

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<TEXT>
Document 6 - file: g4.jpg

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<FILENAME>g5.jpg
<TEXT>
Document 7 - file: g5.jpg

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<FILENAME>g6.jpg
<TEXT>
Document 8 - file: g6.jpg

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<SEQUENCE>9
<FILENAME>g7.jpg
<TEXT>
Document 9 - file: g7.jpg

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<TEXT>
Document 10 - file: g8.jpg

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<TEXT>
Document 11 - file: g9.jpg

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<TEXT>
Document 12 - file: g10.jpg

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<FILENAME>g11.jpg
<TEXT>
Document 13 - file: g11.jpg

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<SEQUENCE>14
<FILENAME>g12.jpg
<TEXT>
Document 14 - file: g12.jpg

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<FILENAME>g13.jpg
<TEXT>
Document 15 - file: g13.jpg

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<SEQUENCE>16
<FILENAME>g14.jpg
<TEXT>
Document 16 - file: g14.jpg

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<DOCUMENT>
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<SEQUENCE>17
<FILENAME>g15.jpg
<TEXT>
Document 17 - file: g15.jpg

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<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>18
<FILENAME>g16.jpg
<TEXT>
Document 18 - file: g16.jpg

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<TYPE>GRAPHIC
<SEQUENCE>19
<FILENAME>g17.jpg
<TEXT>
Document 19 - file: g17.jpg

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<TYPE>GRAPHIC
<SEQUENCE>20
<FILENAME>g18.jpg
<TEXT>
Document 20 - file: g18.jpg

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