Property and Equipment (Details 1) (USD $) In Thousands, unless otherwise specified	Dec. 31, 2014	Dec. 31, 2013
Property, Plant and Equipment
Property, Plant and Equipment, Gross	$ 37,354	$ 123,307
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment	(36,274)	(81,945)
Property, Plant and Equipment, Net	1,080	41,362
Computers and Software
Property, Plant and Equipment
Property, Plant and Equipment, Gross	9,468	11,180
Furniture and Fixtures
Property, Plant and Equipment
Property, Plant and Equipment, Gross	7,032	7,315
Laboratory Equipment
Property, Plant and Equipment
Property, Plant and Equipment, Gross	12,737	34,952
Leasehold Improvements
Property, Plant and Equipment
Property, Plant and Equipment, Gross	8,117	8,092
Buildings
Property, Plant and Equipment
Property, Plant and Equipment, Gross	0	59,104
Land
Property, Plant and Equipment
Property, Plant and Equipment, Gross	$ 0	$ 2,664