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Income Taxes (Tables)
12 Months Ended
Dec. 31, 2014
Income Taxes [Abstract]  
Schedule of Deferred Tax Assets and Liabilities
 
As of December 31,
 
2014
 
2013
 
(in thousands)
Deferred tax assets:
 
 
 
Net operating loss carryforwards
$
255,518

 
$
238,608

Research and development tax credits
40,173

 
37,453

Capitalized research and development
95,946

 
83,375

Stock-based compensation
7,648

 
7,703

Deferred revenue
4,457

 
4,760

Other
8,681

 
4,712

Total deferred tax assets
412,423

 
376,611

Deferred tax liabilities:
 
 
 
Deferred tax liability related to acquisition of Symphony Icon
(18,675
)

(18,745
)
Total deferred tax liabilities
(18,675
)
 
(18,745
)
Less: valuation allowance
(412,423
)
 
(376,611
)
Net deferred tax liabilities
$
(18,675
)
 
$
(18,745
)