Consolidated Statements of Cash Flows (USD $) In Thousands, unless otherwise specified	12 Months Ended
	Dec. 31, 2012	Dec. 31, 2011	Dec. 31, 2010
Cash flows from operating activities:
Consolidated net loss	$ (110,211)	$ (116,215)	$ (101,775)
Adjustments to reconcile consolidated net loss to net cash used in operating activities:
Depreciation	4,190	4,887	5,394
Impairment of fixed assets	0	704	1,001
Amortization of Symphony Icon, Inc. purchase option	0	0	3,957
Increase in fair value of Symphony Icon, Inc. purchase liability	9,887	6,766	2,710
Stock-based compensation	6,495	5,707	5,478
Net gain on auction rate securities ("ARS") and ARS Rights	0	0	(141)
Changes in operating assets and liabilities:
(Increase) decrease in accounts receivable	(1,028)	394	488
(Increase) decrease in prepaid expenses and other current assets	(2,601)	(865)	6,704
(Increase) decrease in other assets	96	414	(218)
Increase (decrease) in accounts payable and other liabilities	(995)	10,365	(5,238)
Decrease in deferred revenue	(293)	(95)	(728)
Net cash used in operating activities	(94,460)	(87,938)	(82,368)
Cash flows from investing activities:
Purchases of property and equipment	(492)	(1,206)	(1,132)
Proceeds from disposal of property and equipment	85	2,625	64
Acquisition of Symphony Icon, Inc., net of cash acquired	0	0	(5,561)
Purchases of investments	(233,250)	(108,092)	(155,856)
Maturities of investments	135,850	176,628	48,641
Net cash provided by (used in) investing activities	(97,807)	69,955	(113,844)
Cash flows from financing activities:
Proceeds from issuance of common stock, net of fees	38,109	160,781	181,496
Repurchase of common stock	(285)	(108)	(149)
Proceeds from debt borrowings	0	0	11,377
Repayment of debt borrowings	(1,443)	(3,589)	(49,858)
Net cash provided by financing activities	36,381	157,084	142,866
Net increase (decrease) in cash and cash equivalents	(155,886)	139,101	(53,346)
Cash and cash equivalents at beginning of year	186,309	47,208	100,554
Cash and cash equivalents at end of year	30,423	186,309	47,208
Supplemental disclosure of cash flow information:
Cash paid for interest	2,028	2,447	2,424
Cash received related to income taxes	0	0	26
Supplemental disclosure of noncash investing and financing activities:
Unrealized gain on investments	2	16	5
Common stock issued in satisfaction of Symphony Icon base payment obligation	35,000	0	0
Intangible assets acquired with long-term liabilities	$ 0	$ 0	$ 43,557