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Property and Equipment (Tables)
12 Months Ended
Dec. 31, 2012
Property and Equipment [Abstract]  
Property, Plant and Equipment [Table Text Block]
 
Estimated Useful Lives
 
As of December 31,
 
In Years
 
2012
 
2011
 
 
 
 
 
(in thousands)
Computers and software
3-5
 
$
11,042

 
$
10,986

Furniture and fixtures
5-7
 
7,343

 
7,391

Laboratory equipment
3-7
 
36,065

 
37,030

Leasehold improvements
7-10
 
9,991

 
9,934

Buildings
15-40
 
58,945

 
58,947

Land
 

 
 
2,664

 
2,664

Total property and equipment
 
 
 
 
126,050

 
126,952

Less: Accumulated depreciation and amortization
 
 
 
 
(83,416
)
 
(80,535
)
Net property and equipment
 
 
 
 
$
42,634

 
$
46,417