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Summary of Significant Accounting Policies Segment Information and Significant Customers (Policies)
12 Months Ended
Dec. 31, 2012
Segment Information and Significant Customers [Abstract]  
Segment Reporting Disclosure [Text Block]
Segment Information and Significant Customers: Lexicon operates in one business segment, which primarily focuses on the discovery of the functions and pharmaceutical utility of genes and the use of those gene function discoveries in the discovery and development of pharmaceutical products for the treatment of human disease. Substantially all of the Company’s revenues have been derived from drug discovery alliances, target validation collaborations for the development and, in some cases, analysis of the physiological effects of genes altered in knockout mice, technology licenses, subscriptions to its databases, government grants and contracts and compound library sales.