Consolidated Statements of Operations (Unaudited) (USD $) In Thousands, except Per Share data	3 Months Ended		6 Months Ended
	Jun. 30, 2011	Jun. 30, 2010	Jun. 30, 2011	Jun. 30, 2010
Revenues:
Collaborative research	$ 461	$ 1,164	$ 977	$ 2,805
Subscription and license fees	94	69	174	69
Total revenues	555	1,233	1,151	2,874
Operating expenses:
Research and development, including stock-based compensation of $818, $809, $1,657 and $1,615, respectively	20,145	20,239	44,066	41,327
Increase in fair value of Symphony Icon, Inc. purchase liability	1,804	0	2,862	0
General and administrative, including stock-based compensation of $632, $511, $1,265 and $1,010, respectively	4,532	5,068	9,285	10,587
Total operating expenses	26,481	25,307	56,213	51,914
Loss from operations	(25,926)	(24,074)	(55,062)	(49,040)
Gain on investments, net	0	53	0	141
Interest income	68	200	155	417
Interest expense	(810)	(729)	(1,417)	(1,456)
Other income (expense), net	30	(643)	57	(1,325)
Consolidated net loss	$ (26,638)	$ (25,193)	$ (56,267)	$ (51,263)
Consolidated net loss per common share, basic and diluted	$ (0.08)	$ (0.07)	$ (0.17)	$ (0.19)
Shares used in computing consolidated net loss per common share, basic and diluted	337,668	337,404	337,598	267,709