EXHIBIT 23.2

                 NOTICE REGARDING CONSENT OF ARTHUR ANDERSEN LLP

         The financial statements of Lexicon Genetics Incorporated as of
December 31, 2001, and for the year then ended, included in this annual report
on Form 10-K have been audited by Arthur Andersen LLP, independent public
accountants. Arthur Andersen LLP has since ceased operations.

         This annual report on Form 10-K is incorporated by reference into
Lexicon's registration statements on Form S-8 (Registration Nos. 333-41532 and
333-66380) and on Form S-3 (Registration Nos. Nos. 333-67294, 333-101549,
333-108855 and 333-111821) and the prospectuses relating thereto. Arthur
Andersen LLP has not reissued its report on Lexicon's financial statements as of
December 31, 2001, and for the year then ended, in connection with this annual
report on Form 10-K. In addition, after reasonable efforts, and in reliance upon
Rule 437a under the Securities Act of 1933, we have not been able to obtain the
consent of Arthur Andersen LLP with respect to the incorporation by reference of
such report in the registration statements and prospectuses referenced above.
Because Arthur Andersen LLP has not consented to the inclusion of such report in
the registration statements and prospectuses referenced above, purchasers under
such prospectuses will not be able to recover against Arthur Andersen LLP under
Section 11(a) of the Securities Act for any untrue statements of a material fact
contained in the financial statements audited by Arthur Andersen LLP or any
omissions to state a material fact required to be stated therein.