10-Q 1 h89868e10-q.txt LEXICON GENETICS INC - JUNE 30, 2001 1 ================================================================================ UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (MARK ONE) [X] QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE QUARTERLY PERIOD ENDED JUNE 30, 2001 OR [ ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO ------------- ------------- COMMISSION FILE NUMBER: 000-30111 LEXICON GENETICS INCORPORATED (EXACT NAME OF REGISTRANT AS SPECIFIED IN ITS CHARTER) DELAWARE 76-0474169 (STATE OR OTHER JURISDICTION OF (I.R.S. EMPLOYER INCORPORATION OR ORGANIZATION) IDENTIFICATION NUMBER) 4000 RESEARCH FOREST DRIVE THE WOODLANDS, TEXAS 77381 (ADDRESS OF PRINCIPAL EXECUTIVE OFFICES AND ZIP CODE) (281) 364-0100 (REGISTRANT'S TELEPHONE NUMBER, INCLUDING AREA CODE) Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports) and (2) has been subject to such filing requirements for the past 90 days. Yes X No --- --- As of August 9, 2001, 51,848,452 shares of the registrant's common stock, par value $0.001 per share, were outstanding. ================================================================================ 2 LEXICON GENETICS INCORPORATED TABLE OF CONTENTS
PAGE ---- FACTORS AFFECTING FORWARD-LOOKING STATEMENTS................................................................. 2 PART I - FINANCIAL INFORMATION Item 1. Financial Statements Balance Sheets - December 31, 2000 and June 30, 2001 (unaudited).................................... 3 Statements of Operations (unaudited) - Three and Six Months Ended June 30, 2000 and 2001............ 4 Statements of Cash Flows (unaudited) - Six Months Ended June 30, 2000 and 2001...................... 5 Notes to Financial Statements (unaudited)........................................................... 6 Item 2. Management's Discussion and Analysis of Financial Condition and Results of Operations............................................................................... 8 Item 3. Quantitative and Qualitative Disclosures About Market Risk.......................................... 15 PART II - OTHER INFORMATION Item 1. Legal Proceedings................................................................................... 15 Item 4. Submission of Matters to a Vote of Security Holders................................................. 15 Item 6. Exhibits and Reports on Form 8-K.................................................................... 16 SIGNATURES .................................................................................................. 17
The Lexicon name and logo and OmniBank(R) are registered trademarks and LexVision(TM), Lexgen.com(TM), Internet Universal(TM) and e-Biology(TM) are trademarks of Lexicon Genetics Incorporated. ------------ FACTORS AFFECTING FORWARD LOOKING STATEMENTS This quarterly report on Form 10-Q contains forward-looking statements. These statements relate to future events or our future financial performance. We have attempted to identify forward-looking statements by terminology including "anticipate," "believe," "can," "continue," "could," "estimate," "expect," "intend," "may," "plan," "potential," "predict," "should" or "will" or the negative of these terms or other comparable terminology. These statements are only predictions and involve known and unknown risks, uncertainties and other factors, including the risks outlined under "Item 2. Management's Discussion and Analysis of Financial Condition and Results of Operations - Risk Factors," that may cause our or our industry's actual results, levels of activity, performance or achievements to be materially different from any future results, levels or activity, performance or achievements expressed or implied by these forward-looking statements. Although we believe that the expectations reflected in the forward-looking statements are reasonable, we cannot guarantee future results, levels of activity, performance or achievements. We are not under any duty to update any of the forward-looking statements after the date of this quarterly report on Form 10-Q to conform these statements to actual results, unless required by law. 2 3 PART I - FINANCIAL INFORMATION ITEM 1. FINANCIAL STATEMENTS LEXICON GENETICS INCORPORATED BALANCE SHEETS
AS OF DECEMBER 31, AS OF JUNE 30, ------------------ ----------------- 2000 2001 ------------------ ----------------- (UNAUDITED) ASSETS Current assets: Cash and cash equivalents ....................................... $ 37,811,039 $ 43,585,316 Marketable securities ........................................... 164,869,291 140,224,465 Accounts receivable, net of allowance for doubtful accounts of $100,000 .................................................. 2,814,707 16,037,920 Prepaid expenses and other current assets ....................... 536,480 3,669,213 ----------------- ----------------- Total current assets ......................................... 206,031,517 203,516,914 Property and equipment, net of accumulated depreciation of $5,708,366 and $7,567,449, respectively ......................... 14,477,235 16,856,415 Other assets ........................................................ 184,200 1,625,156 ----------------- ----------------- Total assets ................................................. $ 220,692,952 $ 221,998,485 ================= ================= LIABILITIES AND STOCKHOLDERS' EQUITY Current liabilities: Accounts payable ................................................ $ 2,522,722 $ 6,458,185 Accrued liabilities ............................................. 3,023,725 1,973,811 Current portion of deferred revenue ............................. 4,671,818 12,041,994 Current portion of long-term debt ............................... 1,012,246 974,368 ----------------- ----------------- Total current liabilities .................................... 11,230,511 21,448,358 Deferred revenue, net of current portion ............................ -- 5,000,000 Long-term debt, net of current portion .............................. 1,833,982 -- ----------------- ----------------- Total liabilities ............................................ 13,064,493 26,448,358 Commitments and contingencies Stockholders' equity: Common stock, $.001 par value; 120,000,000 shares authorized, 48,271,735 and 48,925,613 shares issued and outstanding ...... 48,272 48,926 Additional paid-in capital ...................................... 296,119,625 296,203,689 Deferred stock compensation ..................................... (33,636,725) (27,853,469) Accumulated deficit ............................................. (54,902,713) (72,849,019) ----------------- ----------------- Total stockholders' equity ................................... 207,628,459 195,550,127 ----------------- ----------------- Total liabilities and stockholders' equity ................... $ 220,692,952 $ 221,998,485 ================= =================
The accompanying notes are an integral part of these financial statements. 3 4 LEXICON GENETICS INCORPORATED STATEMENTS OF OPERATIONS (UNAUDITED)
FOR THE THREE MONTHS ENDED JUNE 30, FOR THE SIX MONTHS ENDED JUNE 30, ----------------------------------- ---------------------------------- 2000 2001 2000 2001 --------------- ---------------- --------------- --------------- Revenues: Subscription and license fees ...................... $ 434,574 $ 1,282,366 $ 2,058,052 $ 3,029,820 Collaborative research ............................. 1,989,299 2,199,742 3,634,057 3,723,326 Other revenue ...................................... 158,747 20,330 229,420 60,249 --------------- --------------- --------------- --------------- Total revenues ................................... 2,582,620 3,502,438 5,921,529 6,813,395 Operating expenses: Research and development, including stock-based compensation of $1,460,499, $1,413,078, $8,160,891 and $2,809,608, respectively .......... 5,590,315 10,693,165 15,858,643 20,555,507 General and administrative, including stock-based compensation of $1,773,806, $1,310,599, $6,981,722 and $2,652,383, respectively .......... 3,302,015 5,045,832 9,808,788 9,316,972 --------------- --------------- --------------- --------------- Total operating expenses ........................... 8,892,330 15,738,997 25,667,431 29,872,479 --------------- --------------- --------------- --------------- Loss from operations .................................. (6,309,710) (12,236,599) (19,745,902) (23,059,084) Interest income ....................................... 2,922,316 2,426,919 3,050,158 5,322,810 Interest expense ...................................... 129,310 129,017 239,060 210,032 --------------- --------------- --------------- --------------- Net loss .............................................. (3,516,704) (9,938,657) (16,934,804) (17,946,306) Accretion on redeemable convertible preferred stock ... -- -- (133,854) -- --------------- --------------- --------------- --------------- Net loss attributable to common stockholders .......... $ (3,516,704) $ (9,938,657) $ (17,068,658) $ (17,946,306) =============== =============== =============== =============== Net loss per common share, basic and diluted .......... $ (0.08) $ (0.20) $ (0.48) $ (0.37) Shares used in computing net loss per common share, basic and diluted .................................. 45,816,588 48,865,268 35,214,800 48,672,350
The accompanying notes are an integral part of these financial statements. 4 5 LEXICON GENETICS INCORPORATED STATEMENTS OF CASH FLOWS (UNAUDITED)
FOR THE SIX MONTHS ENDED JUNE 30, ---------------------------------- 2000 2001 --------------- --------------- CASH FLOWS FROM OPERATING ACTIVITIES: Net loss ................................................................. $ (16,934,804) $ (17,946,306) Adjustments to reconcile net loss to net cash provided by (used in) operating activities: Depreciation ........................................................... 1,152,361 2,016,148 Amortization of deferred stock compensation ............................ 15,142,613 5,461,991 Changes in operating assets and liabilities (Increase) decrease in accounts receivable ........................... 1,907,566 (13,223,213) (Increase) decrease in prepaid expenses and other current assets ..... 39,626 (3,132,733) (Increase) decrease in other assets .................................. (12,758) (1,440,956) Increase (decrease) in accounts payable and accrued liabilities ...... 474,552 2,885,549 Increase (decrease) in deferred revenue .............................. (1,223,962) 12,370,176 --------------- --------------- Net cash provided by (used in) operating activities ................ 545,194 (13,009,344) CASH FLOWS FROM INVESTING ACTIVITIES: Purchases of property and equipment ...................................... (1,350,592) (4,395,328) Purchases of marketable securities ....................................... (214,940,362) (210,244,673) Maturities of marketable securities ...................................... 61,061,925 234,889,499 --------------- --------------- Net cash provided by (used in) investing activities ................ (155,229,029) 20,249,498 CASH FLOWS FROM FINANCING ACTIVITIES: Principal payments on capital lease obligations .......................... (111,683) -- Proceeds from issuance of common stock ................................... 203,747,594 405,983 Repayment of debt borrowings ............................................. (1,345,140) (1,871,860) --------------- --------------- Net cash provided by (used in) financing activities ................ 202,290,771 (1,465,877) --------------- --------------- Net increase (decrease) in cash and cash equivalents ........................ 47,606,936 5,774,277 Cash and cash equivalents at beginning of period ............................ 2,025,585 37,811,039 --------------- --------------- Cash and cash equivalents at end of period .................................. $ 49,632,521 $ 43,585,316 =============== =============== SUPPLEMENTAL DISCLOSURE OF CASH FLOW INFORMATION: Cash paid for interest ................................................... $ 239,060 $ 198,271 SUPPLEMENTAL DISCLOSURE OF NON-CASH FINANCING ACTIVITIES: Conversion of redeemable convertible preferred stock into common stock ... $ 30,184,090 $ -- Conversion of related party note payable into common stock ............... $ 337,500 $ --
The accompanying notes are an integral part of these financial statements. 5 6 LEXICON GENETICS INCORPORATED NOTES TO FINANCIAL STATEMENTS (UNAUDITED) 1. BASIS OF PRESENTATION The accompanying unaudited financial statements of Lexicon Genetics Incorporated (Lexicon or the Company) have been prepared in accordance with generally accepted accounting principles for interim financial information and pursuant to the rules and regulations of the Securities and Exchange Commission (SEC). Accordingly, they do not include all of the information and footnotes required by generally accepted accounting principles for complete financial statements. In the opinion of management, all adjustments (consisting of normal recurring adjustments) considered necessary for a fair presentation have been included. Operating results for the three and six month periods ended June 30, 2001 are not necessarily indicative of the results that may be expected for the year ended December 31, 2001. For further information, refer to the financial statements and footnotes thereto included in Lexicon's annual report on Form 10-K for the year ended December 31, 2000, as filed with the SEC. In June 2001, the Financial Accounting Standards Board issued Statement of Financial Accounting Standards No. 141, "Business Combinations" and No. 142, "Goodwill and Other Intangible Assets". These statements, which Lexicon must adopt for 2001, generally require that all business combinations initiated after June 30, 2001, be accounted for using the purchase method. Additionally, any resulting goodwill will not be amortized, rather it will be subject to at least an annual impairment test. Acquired intangible assets must be separately recognized and amortized over their useful lives. Management is currently assessing the impact of these statements on its future financial position and results of operations, which will reflect the July 2001 acquisition of Coelacanth Corporation (see note 7). 2. NET LOSS PER SHARE Net loss per share is computed using the weighted average number of shares of common stock outstanding during the applicable period. Shares associated with stock options and warrants are not included because they are antidilutive. There are no differences between basic and diluted net loss per share for all periods presented. 3. DEFERRED STOCK COMPENSATION Deferred stock compensation represents the difference between the exercise price of stock options and the fair value of Lexicon's common stock at the date of grant. Deferred stock compensation is amortized over the vesting periods of the individual stock options for which it was recorded, generally four years. For the six months ended June 30, 2000 and 2001, Lexicon amortized $15.1 million and $5.5 million, respectively, of deferred stock compensation. If vesting continues in accordance with the outstanding individual stock options, Lexicon expects to record amortization expense for deferred stock compensation as follows: $5.4 million during the last six months of 2001, $10.8 million during 2002, $10.7 million during 2003 and $953,000 during 2004. The amount of stock based compensation expense to be recorded in future periods may decrease if unvested options for which deferred stock compensation 6 7 expense has been recorded are subsequently canceled or forfeited or may increase if additional options are granted to individuals other than employees or directors. 4. INITIAL PUBLIC OFFERING AND CONVERSION OF PREFERRED STOCK In April 2000, Lexicon completed an initial public offering of 10,000,000 newly-issued shares of its common stock at a price of $22.00 per share. Lexicon received $203.2 million in cash, net of underwriting discounts, commissions and other offering costs. Simultaneously with the closing of the initial public offering, the 4,244,664 shares of Redeemable Convertible Series A Preferred Stock then outstanding were automatically converted into 12,733,992 shares of common stock. 5. RESTRICTED CASH The Company is required to maintain restricted cash or investments to the extent of borrowings made under the synthetic lease agreement. As of June 30, 2001, borrowings were $19.9 million as compared to $13.4 million as of December 31, 2000. 6. FINANCING AND DEBT OBLIGATIONS In June 1999, the Company entered into a $5.0 million financing agreement for the purchase of property and equipment. As of June 30, 2001, the Company had drawn down a total of approximately $4.2 million under this arrangement. As of June 30, 2001, $974,000 was outstanding under this arrangement. This facility accrues interest at a weighted-average rate of approximately 11.7% and principal and interest is due in monthly installments through 2003. The Company intends to retire this debt obligation by December 31, 2001, therefore the total obligation has been classified as current debt. A 3% prepayment premium is required upon early extinguishment of the debt and is being accrued as interest expense using the effective interest rate method until the debt is retired. 7. SUBSEQUENT EVENT On July 12, 2001, the Company completed the acquisition of Coelacanth Corporation (Coelacanth) in a merger, under an Agreement and Plan of Merger entered into on June 13, 2001. Under the terms of the merger agreement, the Company issued an aggregate of 2,918,991 shares of common stock in exchange for all of Coelacanth's outstanding capital stock. An aggregate of 10% of the shares of common stock issued in the merger have been placed in escrow for one year to satisfy claims, if any, that the Company may have for breaches of Coelacanth's representations, warranties and covenants in the merger agreement. The Company assumed Coelacanth's outstanding options and warrants in the merger. The Company expects to record intangible assets and expense for in-process research and development in the third quarter of 2001 in connection with the acquisition of Coelacanth. 7 8 ITEM 2. MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS OVERVIEW We are defining the functions of genes for drug discovery using mice whose DNA has been altered to disrupt, or "knock out," the function of the altered gene. Our proprietary gene trapping and gene targeting technologies enable us to rapidly generate these knockout mice by altering the DNA of genes in a special variety of mouse cells, called embryonic stem (ES) cells, which can be cloned and used to generate mice with the altered gene. We employ an integrated platform of advanced medical technologies to systematically analyze the functions and pharmaceutical relevance of the genes we have knocked out. Our LexVision program captures the information resulting from this analysis for our use, and use by our collaborators, to discover pharmaceutical products based on genomics - the study of genes and their function. We derive substantially all of our revenues from subscriptions to our databases, functional genomics collaborations for the development and, in some cases, analysis of the physiological effects of genes altered in knockout mice, and technology licenses. To date, we have generated a substantial portion of our revenues from a limited number of sources. Since our inception, we have incurred significant losses and, as of June 30, 2001, we had an accumulated deficit of $72.8 million. Our losses have resulted principally from costs incurred in research and development, general and administrative costs associated with our operations, and non-cash stock-based compensation expense associated with stock options granted to employees and consultants prior to our April 2000 initial public offering. Research and development expenses consist primarily of salaries and related personnel costs, material costs, legal expenses resulting from intellectual property prosecution and other expenses related to our drug discovery and LexVision programs, the expansion of our OmniBank library, the development and analysis of knockout mice and our other functional genomics research efforts. We expense our research and development costs as they are incurred. General and administrative expenses consist primarily of salaries and related expenses for executive, finance and other administrative personnel, professional fees and other corporate expenses including business development and general legal activities, as well as expenses related to our patent infringement litigation against Deltagen, Inc. In connection with the expansion of our drug discovery and LexVision programs, our OmniBank database and library and our functional genomics research efforts, we expect to incur increasing research and development and general and administrative costs. As a result, we will need to generate significantly higher revenues to achieve profitability. Deferred stock-based compensation represents the difference between the exercise price of stock options granted and the fair value of our common stock at the applicable date of grant. Stock-based compensation is amortized over the vesting period of the individual stock options for which it was recorded, generally four years. Assuming continued vesting of all outstanding stock options in accordance with their terms, we expect to record amortization expense for deferred stock-based compensation as follows: $5.4 million during the last six months of 2001, $10.8 million during 2002, $10.7 million during 2003 and $953,000 during 2004. The amount of stock-based compensation expense to be recorded in future periods may decrease if unvested options for which deferred stock compensation expense has been recorded are subsequently canceled or forfeited or may increase if additional options are granted to non-employee consultants or advisors. Our quarterly operating results will depend upon many factors, including our success in establishing new database subscription and research contracts with collaborators, expirations of such 8 9 contracts, the success rate of our discovery efforts leading to milestones and royalties, the timing and willingness of collaborators to commercialize products which may result in royalties, and general and industry-specific economic conditions which may affect research and development expenditures. As a consequence, our quarterly operating results have fluctuated in the past and are likely to do so in the future. RECENT DEVELOPMENTS On July 12, 2001, we completed the acquisition of Coelacanth Corporation in a merger, under an Agreement and Plan of Merger entered into on June 13, 2001. Coelacanth, which uses proprietary chemistry technologies to rapidly discover new chemical entities for drug development, forms the core for our new Lexicon Pharmaceuticals division, based in Princeton, New Jersey. In Lexicon Pharmaceuticals, we are combining our drug target discoveries with Coelacanth's high performance chemistry technologies to discover potential new drugs. Under the terms of the merger agreement, the Company issued an aggregate of 2,918,991 shares of common stock in exchange for all of Coelacanth's outstanding capital stock. An aggregate of 10% of the shares of common stock issued in the merger have been placed in escrow for one year to satisfy claims, if any, that the Company may have for breaches of Coelacanth's representations, warranties and covenants in the merger agreement. The Company assumed Coelacanth's outstanding options and warrants in the merger. RESULTS OF OPERATIONS Three Months Ended June 30, 2000 and 2001 Revenues. Total revenues increased 36% to $3.5 million in the three months ended June 30, 2001 from $2.6 million in the corresponding period in 2000. Of the $920,000 increase, $848,000 was derived from increased database subscription and technology license fees and $210,000 was derived from increased revenues from collaborative research. This was offset by a $138,000 decrease in other revenue. In June 2001, we entered into a series of agreements with Incyte Genomics, Inc. (Incyte), including a drug discovery alliance under which we and Incyte will collaborate in the discovery and development of therapeutic proteins and a separate agreement under which Incyte will have access to our LexVision database and OmniBank database and library. In addition, as a result of our acquisition of Coelacanth in July 2001, we obtained or have subsequently entered agreements with pharmaceutical and biotechnology companies for access to chemical libraries and optimization services. We have not yet recognized any revenues under any of these agreements. Research and Development Expenses. Research and development expenses, including stock-based compensation expense, increased 91% to $10.7 million in the three months ended June 30, 2001 from $5.6 million in the corresponding period in 2000. Research and development expenses for the three months ended June 30, 2001 and 2000 included $1.4 million and $1.5 million, respectively, of stock-based compensation primarily relating to option grants made prior to our April 2000 initial public offering. The increase of $5.2 million in research and development expenses exclusive of stock-based compensation was primarily attributable to increased personnel costs to support the expansion of our drug discovery and LexVision programs, our OmniBank database and library, the development and analysis of knockout mice and our other functional genomics research efforts. We expect to record expense for in-process research and development in the third quarter of 2001 in connection with our acquisition of Coelacanth. In addition, we expect to incur increased research and 9 10 development expenses in the third quarter and subsequent periods as a result of our acquisition of Coelacanth and agreements entered in June 2001 with Incyte for access and license rights to Incyte's LifeSeq(R) Gold database General and Administrative Expenses. General and administrative expenses, including stock-based compensation expense, increased 53% to $5.0 million in the three months ended June 30, 2001 from $3.3 million in the corresponding period in 2000. General and administrative expenses for the three months ended June 30, 2001 and 2000 included $1.3 million and $1.8 million, respectively, of stock-based compensation primarily relating to option grants made prior to our April 2000 initial public offering. The increase of $2.2 million in general and administrative expenses exclusive of stock-based compensation was due primarily to additional personnel costs for business development and finance and administration, as well as expenses associated with our patent infringement litigation against Deltagen, Inc. We expect to incur increased general and administrative expenses in future periods as a result of our acquisition of Coelacanth. Interest Income and Interest Expense. Interest income decreased to $2.4 million in the three months ended June 30, 2001 from $2.9 million in the corresponding period in 2000. This decrease resulted from lower interest rates and decreased average cash and investment balances during the 2001 period. Interest expense was $129,000 in each of the three-month periods ended June 30, 2001 and 2000, respectively. Net Loss and Net Loss Per Common Share. Net loss attributable to common stockholders increased to $9.9 million in the three months ended June 30, 2001 from $3.5 million in the corresponding period in 2000. Net loss per common share increased to $0.20 in the three months ended June 30, 2001 from $0.08 in the corresponding period of 2000. A portion of the net loss for the three months ended June 30, 2001 and most of the net loss for the corresponding period in 2000 were attributable to stock-based compensation expense. Excluding stock-based compensation expense, and assuming the conversion of the redeemable convertible preferred stock into common stock occurred on the date of original issuance (May 1998), we would have had a net loss of $7.2 million and $282,000 in the three months ended June 30, 2001 and 2000, respectively, and net loss per common share of $0.15 and $0.01 in the three months ended June 30, 2001 and 2000, respectively. Six Months Ended June 30, 2000 and 2001 Revenues. Total revenues increased 15% to $6.8 million in the six months ended June 30, 2001 from $5.9 million in the corresponding period in 2000. Of the $892,000 increase, $972,000 was derived from increased database subscription and technology license fees and $89,000 was derived from increased revenues from collaborative research. This was offset by a $169,000 decrease in other revenue. Research and Development Expenses. Research and development expenses, including stock-based compensation expense, increased 30% to $20.6 million in the six months ended June 30, 2001 from $15.9 million in the corresponding period in 2000. Research and development expenses for the six months ended June 30, 2001 and 2000 included $2.8 million and $8.2 million, respectively, of stock-based compensation primarily relating to option grants made prior to our April 2000 initial public offering. The increase of $10.0 million in research and development expenses exclusive of stock-based compensation was primarily attributable to increased personnel costs to support the expansion of our drug discovery and LexVision programs, our OmniBank database and library, the development and analysis of knockout mice and our other functional genomics research efforts. General and Administrative Expenses. General and administrative expenses, including stock-based compensation expense, decreased 5% to $9.3 million in the six months ended June 30, 2001 from 10 11 $9.8 million in the corresponding period in 2000. General and administrative expenses for the six months ended June 30, 2001 and 2000 included $2.7 million and $7.0 million, respectively, of stock-based compensation primarily relating to option grants made prior to our April 2000 initial public offering. The increase of $3.8 million in general and administrative expenses exclusive of stock-based compensation was due primarily to additional personnel costs for business development and finance and administration, as well as expenses associated with our patent infringement litigation against Deltagen, Inc. Interest Income and Interest Expense. Interest income increased to $5.3 million in the six months ended June 30, 2001 from $3.1 million in the corresponding period in 2000. This increase resulted from increased average cash and investment balances during the 2001 period as a result of our initial public offering in April 2000. Interest expense decreased to $210,000 in the six months ended June 30, 2001 from $239,000 in the corresponding period in 2000. Net Loss and Net Loss Per Common Share. Net loss attributable to common stockholders increased to $17.9 million in the six months ended June 30, 2001 from $17.1 million in the corresponding period in 2000. Net loss per common share decreased to $0.37 in the six months ended June 30, 2001 from $0.48 in the corresponding period of 2000. A portion of the net loss for the six months ended June 30, 2001 and most of the net loss for the corresponding period in 2000 were attributable to stock-based compensation expense. Excluding stock-based compensation expense, and assuming the conversion of the redeemable convertible preferred stock into common stock occurred on the date of original issuance (May 1998), we would have had a net loss of $12.5 million and $1.8 million in the six months ended June 30, 2001 and 2000, respectively, and net loss per common share of $0.26 and $0.04 in the six months ended June 30, 2001 and 2000, respectively. RECENT ACCOUNTING PRONOUNCEMENTS In June 2001, the Financial Accounting Standards Board issued Statement of Financial Accounting Standards No. 141, "Business Combinations" and No. 142, "Goodwill and Other Intangible Assets". These statements, which Lexicon must adopt for 2001, generally require that all business combinations initiated after June 30, 2001, be accounted for using the purchase method. Additionally, any resulting goodwill will not be amortized, but rather will be subject to at least an annual impairment test. Acquired intangible assets will be separately recognized and amortized over their useful lives. Management is currently assessing the impact of these statements on its future financial position and results of operations, which will reflect the July 2001 acquisition of Coelacanth Corporation. LIQUIDITY AND CAPITAL RESOURCES We have financed our operations from inception primarily through sales of common and preferred stock, contract and milestone payments to us under our database subscription and collaboration agreements and equipment financing arrangements. From our inception through June 30, 2001, we had received net proceeds of $241.8 million from issuances of common and preferred stock, including $203.2 million of net proceeds from the initial public offering of our common stock in April 2000. In addition, from our inception through June 30, 2001, we received $30.4 million in cash payments from database subscription and technology license fees, functional genomics collaborations for the development and analysis of knockout mice, sales of reagents and government grants, and have recognized revenues of $29.5 million through June 30, 2001. As of June 30, 2001, we had $183.8 million in cash, cash equivalents and marketable securities, as compared to $202.7 million as of December 31, 2000. We used $13.0 million in operations in the six months ended June 30, 2001. This consisted of the net loss for the six months ended June 30, 2001 of $17.9 million offset by non-cash charges of $5.4 million related to stock-based compensation expense and 11 12 $2.0 million related to depreciation expense, which in turn was offset by a $2.5 million net increase in other working capital accounts and long-term deferred revenue. Investing activities provided $20.2 million in the six months ended June 30, 2001, principally as a result of maturities of marketable securities. In June 1999, we entered into a $5.0 million financing arrangement for the purchase of property and equipment which is secured by the equipment financed. We borrowed a total of approximately $4.2 million under this arrangement, of which $974,000 remained outstanding at June 30, 2001. This facility accrues interest at a weighted-average rate of approximately 11.7%, and principal and interest is due in monthly installments through 2003. The debt is being retired through prepayment beginning in the second quarter of 2001. In October 2000, we entered into a synthetic lease agreement under which the lessor purchased our current laboratory and office space and animal facility and agreed to fund the construction of additional laboratory and office space and a second animal facility. Including the purchase price for our existing facilities, the synthetic lease provides for funding of up to $45.0 million in property and improvements. The term of the agreement is six years, which includes the construction period and a lease period. Lease payments for the new facilities will begin upon completion of construction, which is expected in the fourth quarter of 2001. Lease payments are subject to fluctuation based on LIBOR rates. At the end of the lease term, the lease may be extended for one-year terms, up to seven additional terms, or we may purchase the properties for a price including the outstanding lease balance. If we elect not to renew the lease or purchase the properties, we must arrange for the sale of the properties to a third party. Under the sale option, we have guaranteed a percentage of the total original cost as the residual fair value of the properties. The Company is required to maintain restricted cash or investments to the extent of borrowings made under the synthetic lease agreement. As of June 30, 2001, borrowings were $19.9 million as compared to $13.4 million as of December 31, 2000. Our capital requirements depend on numerous factors, including our ability to obtain database subscription and collaboration agreements, the amount and timing of payments under such agreements, the level and timing of our research and development expenditures, market acceptance of our products, the resources we devote to developing and supporting our products and other factors. We expect to devote substantial capital resources to continue our research and development efforts, to expand our support and product development activities, and for other general corporate activities. We believe that our current cash balances, together with revenues to be derived from subscriptions to our databases, functional genomics collaborations for the research, development and analysis of the physiological effects of genes altered in knockout mice, will be sufficient to fund our operations for at least the next several years. During or after this period, if cash generated by operations is insufficient to satisfy our liquidity requirements, we may need to sell additional equity or debt securities or obtain additional credit arrangements. Additional financing may not be available on terms acceptable to us or at all. The sale of additional equity or convertible debt securities may result in additional dilution to our stockholders. IMPACT OF INFLATION The effect of inflation and changing prices on our operations was not significant during the periods presented. DISCLOSURE ABOUT MARKET RISK Our exposure to market risk is confined to our cash and cash equivalents which have maturities of less than three months. We maintain an investment portfolio which consists of U.S. government debt obligations and investment grade commercial paper that mature one to twelve months after June 30, 2001, 12 13 which we believe are subject to limited credit risk. We currently do not hedge interest rate exposure. Because of the short-term maturities of our investments, we believe that changes in market rates would not have any negative impact on the realized value of our investment portfolio. We have operated primarily in the United States and substantially all sales to date have been made in U.S. dollars. Accordingly, we have not had any material exposure to foreign currency rate fluctuations. RISK FACTORS Our business is subject to certain risks and uncertainties, including those referenced below: Risks Related to Our Business o we have a history of net losses, and we expect to continue to incur net losses and may not achieve or maintain profitability o our quarterly operating results have been and likely will continue to fluctuate, and we believe that quarter-to-quarter comparisons of our operating results are not a good indication of our future performance o we are an early-stage company with an unproven business strategy o we face substantial competition in the discovery of the DNA sequences of genes and their functions and in our drug discovery and product development efforts o we rely heavily on collaborators to develop and commercialize pharmaceutical products based on genes that we identify as promising candidates for development as drug targets o any cancellation by or conflicts with our collaborators could harm our business o we have no experience in developing and commercializing pharmaceutical products on our own o we may engage in future acquisitions, which may be expensive and time consuming and from which we may not realize anticipated benefits o if we lose our key personnel or are unable to attract and retain additional personnel, we may be unable to pursue collaborations or develop our own products o we may encounter difficulties in managing our growth, which could increase our losses o because our entire OmniBank mouse clone library is located at a single facility, the occurrence of a disaster could significantly disrupt our business o we can provide no assurance that we will prevail in our claims against Deltagen, Inc. or that, if we prevail, any damages or equitable remedies awarded will be commercially valuable o we may need additional capital in the future and, if it is not available, we may have to curtail or cease operations 13 14 Risks Related to Our Industry o our ability to patent our discoveries is uncertain because patent laws and their interpretation are highly uncertain and subject to change o our patent applications may not result in enforceable patent rights o if other companies and institutions obtain patents claiming the functional uses of genes and gene products based upon gene sequence information and predictions of gene function, we may be unable to obtain patents for our discoveries of biological function in knockout mice o we are presently involved in patent litigation and may be involved in future patent litigation and other disputes regarding intellectual property rights, and can give no assurance that we will prevail in any such litigation or other dispute o issued patents may not fully protect our discoveries, and our competitors may be able to commercialize products similar to those covered by our issued patents o our rights to the use of technologies licensed by third parties are not within our control o we may be unable to protect our trade secrets o we may become subject to regulation under the Animal Welfare Act, which could subject us to additional costs and permit requirements o we and our collaborators are subject to extensive and uncertain government regulatory requirements, which could increase our operating costs or adversely affect our ability to obtain government approval of products based on genes that we identify in a timely manner or at all o security risks in electronic commerce or unfavorable internet regulation may deter future use of our products and services o we use hazardous chemicals and radioactive and biological materials in our business; any disputes relating to improper handling, storage or disposal of these materials could be time consuming and costly o we may be sued for product liability o public perception of ethical and social issues may limit or discourage the use of our technologies, which could reduce our revenues For additional discussion of the risks and uncertainties that affect our business, see "Item 1. Business - Risk Factors" included in our annual report on Form 10-K for the year ended December 31, 2000, as filed with the Securities and Exchange Commission. 14 15 ITEM 3. QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK See "Disclosure about Market Risk" under "Item 2. Management's Discussion and Analysis of Financial Condition and Results of Operations for quantitative and qualitative disclosures about market risk. PART II - OTHER INFORMATION ITEM 1. LEGAL PROCEEDINGS On May 24, 2000, we filed a complaint against Deltagen, Inc. in U.S. District Court for the District of Delaware alleging that Deltagen is willfully infringing the claims of United States Patent No. 5,789,215, under which we hold an exclusive license from GenPharm International, Inc. This patent covers methods of engineering the animal genome, including methods for the production of knockout mice by homologous recombination, using isogenic DNA technology. In the complaint, we are seeking unspecified damages from Deltagen, as well as injunctive relief. Deltagen has counterclaimed for a declaratory judgment that the patent is invalid and unenforceable and is not infringed by Deltagen. On November 14, 2000, Deltagen filed an amended counterclaim alleging antitrust claims against us and GenPharm, for which Deltagen is seeking unspecified damages. The Markman hearing with respect to the claims of the isogenic DNA patent is currently scheduled for October 4, 2001. On October 13, 2000, we filed a second complaint against Deltagen, Inc. in U.S. District Court for the Northern District of California alleging that Deltagen is willfully infringing the claims of United States Patents Nos. 5,464,764, 5,487,992, 5,627,059, and 5,631,153, under which also we hold exclusive licenses from GenPharm International. These patents cover methods and vectors for using positive-negative selection for producing gene targeted, or "knockout," cells and animals, including the production of knockout mice by homologous recombination. In the complaint, we are seeking unspecified damages from Deltagen, as well as injunctive relief. Deltagen has counterclaimed for a declaratory judgment that the patents are invalid and unenforceable and are not infringed by Deltagen. While we believe that our complaints against Deltagen are meritorious and that Deltagen's counterclaims against us are without merit, we can provide no assurance that we will prevail in our litigation against Deltagen or that, if we prevail, any damages or equitable remedies awarded will be commercially valuable. If Deltagen prevails in declaring our patents invalid or on its antitrust claim against us, our business and financial position could be adversely affected. Furthermore, we are likely to incur substantial costs and expend substantial personnel time in pursuing our litigation against Deltagen. We are not a party to any material legal proceedings other than the Deltagen litigation. ITEM 4. SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS Our annual meeting of stockholders was held on April 18, 2001 to consider and vote upon the following proposals: (1) The following individual was nominated and elected as a Class I director, with the following numbers of shares voted for and withheld for such director:
NAME OF DIRECTOR FOR WITHHELD ---------------- --- -------- Robert J. Lefkowitz, M.D. 39,235,702 19,279
15 16 (2) The following additional matter was considered and approved, with the following numbers of shares voted for, voted against and abstaining with respect to such matter:
MATTER FOR AGAINST ABSTAIN ------ --- ------- ------- Appointment of Arthur Andersen LLP as our independent public accountants for the fiscal year ending December 31, 2001 39,208,234 39,821 6,926
ITEM 6. EXHIBITS AND REPORTS ON FORM 8-K (a) Exhibits EXHIBIT NO. DESCRIPTION 10.1 -- Agreement and Plan of Merger, dated June 13, 2001, among Lexicon Genetics Incorporated, Angler Acquisition Corp. and Coelacanth Corporation (filed as Exhibit 10.1 to the company's Current Report on Form 8-K dated June 13, 2001 and incorporated by reference herein). +10.2 -- LexVision Database and Collaboration Agreement, dated June 27, 2001, between Lexicon Genetics Incorporated and Incyte Genomics, Inc. +10.3 -- Therapeutic Protein Alliance Agreement, dated June 27, 2001, between Lexicon Genetics Incorporated and Incyte Genomics, Inc. ------------------------ + Confidential treatment has been requested for a portion of this exhibit. The confidential portions of this exhibit have been omitted and filed separately with the Securities and Exchange Commission. (b) Reports on Form 8-K: On June 18, 2001, we filed a Current Report on Form 8-K dated June 13, 2001 relating to our execution of an Agreement and Plan of Merger providing for our acquisition of Coelacanth Corporation. 16 17 SIGNATURES Pursuant to the requirements of the Securities Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized. LEXICON GENETICS INCORPORATED Date: August 14, 2001 By: /s/ ARTHUR T. SANDS --------------------------------- Arthur T. Sands, M.D., Ph.D. President and Chief Executive Officer Date: August 14, 2001 By: /s/ JULIA P. GREGORY --------------------------------- Julia P. Gregory Executive Vice President and Chief Financial Officer 17 18 INDEX TO EXHIBITS
EXHIBIT NO. DESCRIPTION ----------- ----------- 10.1 -- Agreement and Plan of Merger, dated June 13, 2001, among Lexicon Genetics Incorporated, Angler Acquisition Corp. and Coelacanth Corporation (filed as Exhibit 10.1 to the company's Current Report on Form 8-K dated June 13, 2001 and incorporated by reference herein). +10.2 -- LexVision Database and Collaboration Agreement, dated June 27, 2001, between Lexicon Genetics Incorporated and Incyte Genomics, Inc. +10.3 -- Therapeutic Protein Alliance Agreement, dated June 27, 2001, between Lexicon Genetics Incorporated and Incyte Genomics, Inc. ------------------------ + Confidential treatment has been requested for a portion of this exhibit. The confidential portions of this exhibit have been omitted and filed separately with the Securities and Exchange Commission.