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                                                                    EXHIBIT 23.1

                    CONSENT OF INDEPENDENT PUBLIC ACCOUNTANTS


As independent public accountants, we hereby consent to the incorporation of our
report included in this Form 10-K into Lexicon Genetics Incorporated's
previously filed Registration Statement on Form S-8 (Registration No. 333-41532)
dated July 14, 2000.



ARTHUR ANDERSEN LLP


Houston, Texas
March 12, 2001