Exhibit 99.1 This Statement on Form 4 is filed by the Reporting Persons listed below. Name of Designated Filer: INVUS PUBLIC EQUITIES, L.P. Date of Event Requiring Statement: December 16, 2020. Issuer Name: Lexicon Pharmaceuticals, Inc. [LXRX] INVUS PUBLIC EQUITIES, L.P. By: INVUS PUBLIC EQUITIES ADVISORS, LLC, its general partner By: /s/ Raymond Debbane ------------------- Name: Raymond Debbane Title: President INVUS L.P. By: INVUS ADVISORS, L.L.C., its general partner By: /s/ Raymond Debbane ------------------- Name: Raymond Debbane Title: President INVUS PUBLIC EQUITIES ADVISORS, LLC By: /s/ Raymond Debbane ------------------- Name: Raymond Debbane Title: President INVUS ADVISORS, L.L.C. By: /s/ Raymond Debbane ------------------- Name: Raymond Debbane Title: President ARTAL TREASURY LIMITED By: /s/ Keith Le Poidevin ------------------- Name: Keith Le Poidevin Title: Director