Consolidated Balance Sheets - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Current assets:
Cash and cash equivalents	$ 112,666	$ 82,985
Short-term investments	358,972	381,075
Accounts receivable	51,819	4,420
Prepaid expenses and other current assets	12,215	5,741
Total current assets	535,672	474,221
Long-term investments	152,050	36,954
Property and equipment, net	73,271	13,346
Operating lease right-of-use assets	73,138	2,924
Other assets	7,188	6,358
Total assets	841,319	533,803
Current liabilities:
Accounts payable	21,087	8,050
Accrued liabilities	34,370	19,315
Short-term operating lease liabilities	14,863	2,785
Other current liabilities	1,540	1,049
Total current liabilities	71,860	31,199
Term loan, net	47,367	46,209
Convertible notes, net	95,471	89,504
Liabilities related to revenue participation right purchase agreement, net	179,072	166,068
Long-term deferred revenue	87,000	87,000
Long-term operating lease liabilities	112,229	440
Other non-current liabilities	4,457	0
Total liabilities	597,456	420,420
Commitments and contingencies	0	0
Stockholders’ equity:
Preferred stock, $0.001 par value: Authorized: 10,000,000 shares; Issued and outstanding: none	0	0
Common stock, $0.001 par value: Authorized: 163,000,000 shares; Issued and outstanding: 84,799,542 shares at December 31, 2021 and 71,015,183 shares at December 31, 2020	84	70
Additional paid-in capital	1,452,268	1,105,470
Accumulated other comprehensive (loss) income	(869)	149
Accumulated deficit	(1,207,620)	(992,306)
Total stockholders’ equity	243,863	113,383
Total liabilities and stockholders’ equity	$ 841,319	$ 533,803