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Balance Sheet Components - Summary of Property and Equipment (Detail) - USD ($)
$ in Thousands
Dec. 31, 2020
Dec. 31, 2019
Property Plant And Equipment [Line Items]    
Total property and equipment $ 37,987 $ 28,725
Less: Accumulated depreciation and amortization (24,641) (24,195)
Total property and equipment, net 13,346 4,530
Laboratory Equipment [Member]    
Property Plant And Equipment [Line Items]    
Total property and equipment 18,160 18,741
Computer Equipment and Software [Member]    
Property Plant And Equipment [Line Items]    
Total property and equipment 2,940 2,940
Office Equipment, Furniture and Fixtures [Member]    
Property Plant And Equipment [Line Items]    
Total property and equipment 1,885 1,823
Leasehold Improvements [Member]    
Property Plant And Equipment [Line Items]    
Total property and equipment 5,872 5,221
Construction in Progress [Member]    
Property Plant And Equipment [Line Items]    
Total property and equipment $ 9,130 $ 0