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Statements of Stockholders' Equity (Deficit) (USD $)
In Thousands, except Share data
Total
USD ($)
MLV [Member]
USD ($)
Common Stock [Member]
USD ($)
Common Stock [Member]
MLV [Member]
USD ($)
Common Stock [Member]
Series A Convertible Preferred Stock [Member]
USD ($)
Common Stock [Member]
Series B Convertible Preferred Stock [Member]
USD ($)
Preferred Stock [Member]
Preferred Stock [Member]
Series A Convertible Preferred Stock [Member]
Preferred Stock [Member]
Series B Convertible Preferred Stock [Member]
Additional Paid-In Capital [Member]
USD ($)
Additional Paid-In Capital [Member]
MLV [Member]
USD ($)
Additional Paid-In Capital [Member]
Series A Convertible Preferred Stock [Member]
USD ($)
Additional Paid-In Capital [Member]
Series B Convertible Preferred Stock [Member]
USD ($)
Accumulated Other Comprehensive Income (Loss) [Member]
USD ($)
Accumulated Deficit [Member]
USD ($)
Beginning Balance at Dec. 31, 2010 $ 70,516   $ 11             $ 431,159       $ (4) $ (360,650)
Beginning Balance, shares at Dec. 31, 2010     11,151,267                        
Issuance of common stock upon exercise of stock options for cash at $ 6.00-$7.20 and $4.02-$11.10 per share in 2011 and 2013 respectively 17                 17          
Issuance of common stock upon exercise of stock options for cash, shares     2,667                        
Issuance of common stock pursuant to ESPP at a weighted price of $4.32 and $3.66 per share in 2012 and 2013 respectively 6,127                 6,126          
Issuance of common stock pursuant to ESPP, shares     18,822                        
Issuance of common stock at $9.00 and $4.56 per share, net of issuance costs of $53 and $2,139 in 2011 and 2012 respectively 6,127   1             6,126          
Issuance of common stock, shares     883,333                        
Issuance of convertible preferred stock at $1500 per share and $760 per share, net of issuance costs of $81 and $881 in 2011 and 2012 respectively 9,329                 9,329          
Issuance of convertible preferred stock, shares             8,070                
Issuance of warrants, net of issuance costs of $38 and $984 in 2011 and 2012 respectively 4,427                 4,427          
Issuance of common stock to MLV at $6.00-$6.12, $6.30-$7.20 and $6.50-$6.79 per share in 2011, 2012 and 2013 respectively, net of commission and issuance costs of $160, $89 and $232 in 2012 and 2013 respectively   2,421   1             2,420        
Issuance of common stock to MLV, shares       429,868                      
Stock-based compensation 3,069                 3,069          
Other comprehensive income (loss) 7                         7  
Net income (loss) (47,860)                           (47,860)
Ending Balance at Dec. 31, 2011 48,178   13             456,672       3 (408,510)
Ending Balance, shares at Dec. 31, 2011     12,485,957       8,070                
Issuance of common stock pursuant to ESPP at a weighted price of $4.32 and $3.66 per share in 2012 and 2013 respectively 65                 65          
Issuance of common stock pursuant to ESPP, shares     15,010                        
Issuance of common stock upon exercise of restricted stock units, value (401)                 (401)          
Issuance of common stock upon exercise of restricted stock units, shares     144,045                        
Issuance of common stock at $9.00 and $4.56 per share, net of issuance costs of $53 and $2,139 in 2011 and 2012 respectively 29,916   9             29,907          
Issuance of common stock, shares     9,320,176                        
Issuance of convertible preferred stock at $1500 per share and $760 per share, net of issuance costs of $81 and $881 in 2011 and 2012 respectively 12,318                 12,318          
Issuance of convertible preferred stock, shares             23,026                
Issuance of warrants, net of issuance costs of $38 and $984 in 2011 and 2012 respectively 13,761                 13,761          
Conversion of preferred stock to common stock, value         1             (1)      
Conversion of convertible preferred stock to common stock at $1,000 per share         1,345,000     (8,070)              
Issuance of common stock to MLV at $6.00-$6.12, $6.30-$7.20 and $6.50-$6.79 per share in 2011, 2012 and 2013 respectively, net of commission and issuance costs of $160, $89 and $232 in 2012 and 2013 respectively   2,820   1             2,819        
Issuance of common stock to MLV, shares       432,724                      
Stock-based compensation 3,783                 3,783          
Other comprehensive income (loss) 15                         15  
Net income (loss) (40,370)                           (40,370)
Ending Balance at Dec. 31, 2012 70,085   24             518,923       18 (448,880)
Ending Balance, shares at Dec. 31, 2012     23,742,912       23,026                
Issuance of common stock upon exercise of stock options for cash at $ 6.00-$7.20 and $4.02-$11.10 per share in 2011 and 2013 respectively 114                 114          
Issuance of common stock upon exercise of stock options for cash, shares     21,397                        
Issuance of common stock pursuant to ESPP at a weighted price of $4.32 and $3.66 per share in 2012 and 2013 respectively 55                 55          
Issuance of common stock pursuant to ESPP, shares     14,985                        
Issuance of common stock upon exercise of restricted stock units, value (623)                 (623)          
Issuance of common stock upon exercise of restricted stock units, shares     130,534                        
Issuance of common stock to related party for $7.12 per share, net of issuance costs of $21 7,450   2             7,448          
Issuance of common stock to related party, shares     1,404,100                        
Issuance of common stock upon exercise of warrants 5                 5          
Issuance of common stock upon exercise of warrants, shares     359,460                        
Conversion of preferred stock to common stock, value           4             (4)    
Conversion of convertible preferred stock to common stock at $1,000 per share           3,837,681     (23,026)            
Fractional shares settlement pursuant to reverse stock split 0   (28)                        
Issuance of common stock to MLV at $6.00-$6.12, $6.30-$7.20 and $6.50-$6.79 per share in 2011, 2012 and 2013 respectively, net of commission and issuance costs of $160, $89 and $232 in 2012 and 2013 respectively   7,487   1             7,486        
Issuance of common stock to MLV, shares       1,170,583                      
Stock-based compensation 3,597                 3,597          
Other comprehensive income (loss) (11)                         (11)  
Net income (loss) (33,717)                           (33,717)
Ending Balance at Dec. 31, 2013 $ 54,442   $ 31             $ 537,001       $ 7 $ (482,597)
Ending Balance, shares at Dec. 31, 2013     30,681,624