6-K

FORM 6-K

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

Report of Foreign Private Issuer

Pursuant to Rule 13a-16 under

the Securities Exchange Act of 1934

For the month ended July, 2011

ICON plc

(Registrant's name)

0-29714

(Commission file number)

South County Business Park, Leopardstown, Dublin 18, Ireland

(Address of principal executive offices)

Ciaran Murray, CFO

South County Business Park Leopardstown, Dublin 18, Ireland.

Ciaran.Murray@iconplc.com

011-353-1-291-2000

(Name, telephone number, email and/or facsimile number and address of Company contact person)

Indicate by check mark whether the registrant files or will file annual reports under cover Form 20-F or Form 40-F.
	Yes___X___	No_______
Indicate by check mark whether the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1):
	Yes______	No___X___
Indicate by check mark whether the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(7):
	Yes______	No___X___
Indicate by check mark whether the registrant by furnishing the information contained in this Form is also thereby furnishing the information to the Commission pursuant to Rule12g3-2(b) under the Securities Exchange Act of 1934.
	Yes______	No___X___
If "Yes" is marked, indicate below the file number assigned to the registrant in connection with Rule 12g3-2(b):82 N/A

ICON plc

This report on Form 6-K is hereby incorporated by reference in the registration statement on Form F-3 (Registration No. 333-133371) of ICON plc and in the prospectus contained therein, and this report on Form 6-K shall be deemed a part of such registration statement from the date on which this report is filed, to the extent not superseded by documents or reports subsequently filed or furnished by ICON plc under the Securities Act of 1933 or the Securities Exchange Act of 1934.

1

ICON plc

GENERAL

As used herein, “ICON”, the “Company” and “we” refer to ICON plc and its consolidated subsidiaries, unless the context requires otherwise.

Business

We are a contract research organization (“CRO”), providing outsourced development services on a global basis to the pharmaceutical, biotechnology and medical device industries. We specialize in the strategic development, management and analysis of programs that support Clinical Development - from compound selection to Phase I-IV clinical studies.

We believe that we are one of a select group of CROs with the capability and expertise to conduct clinical trials in most major therapeutic areas on a global basis. At June 30, 2011 we had approximately 7,800 employees, in 77 locations in 39 countries, providing Phase I - IV Clinical Trial Management, Drug Development Support Services, Data Management and Biostatistical, Central Laboratory, Imaging and Contract Staffing services. We have the operational flexibility to provide development services on a stand-alone basis or as part of an integrated “full service” solution.

Headquartered in Dublin, Ireland, we began operations in 1990 and have expanded our business through internal growth and strategic acquisitions. ICON plc’s principal executive office is located at: South County Business Park, Leopardstown, Dublin 18, Republic of Ireland. The contact telephone number of this office is 353 (1) 291 2000. For the three months ended June 30, 2011 we derived approximately 40.3%, 47.2% and 12.5% of our net revenue in the United States, Europe and Rest of World, respectively.

Recent Developments

Acquisitions

On July 13, 2011 the Company acquired Firecrest Clinical, a market leading provider of technology solutions that boost investigator site performance and study management. Headquartered in Limerick, Ireland, Firecrest Clinical provides a comprehensive site performance management system that is used to improve compliance consistency and executivion of activities at investigative sites.

On January 14, 2011 the Company acquired Oxford Outcomes, a leading international health outcomes consultancy, headquartered in Oxford, UK, and with offices in the USA and Canada.  Oxford Outcomes provides specialist services in the areas of patient reported outcomes (PRO), health economics, epidemiology and translation and linguistic validation.

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ICON plc

CONDENSED CONSOLIDATED BALANCE SHEETS

AS AT JUNE 30, 2011 AND DECEMBER 31, 2010

	(Unaudited)		(Audited)
	June 30,		December 31,
	2011		2010
ASSETS	(in thousands)
Current Assets:
Cash and cash equivalents	$	175,564	$	255,706
Short term investments - available for sale		40,000		-
Accounts receivable		171,014		164,907
Unbilled revenue		143,323		101,431
Other receivables		17,643		12,451
Deferred tax asset		7,700		5,623
Prepayments and other current assets		22,573		20,592
Income taxes receivable		17,969		18,966
Total current assets		595,786		579,676
Other Assets:
Property, plant and equipment, net		175,132		170,861
Goodwill		219,611		175,860
Non-current other assets		4,538		4,353
Non-current income taxes receivable		475		482
Non-current deferred tax asset		11,477		10,028
Intangible assets		7,230		8,278
Total Assets	$	1,014,249	$	949,538
LIABILITIES AND SHAREHOLDERS’ EQUITY
Current Liabilities:
Accounts payable	$	4,291	$	12,314
Payments on account		142,345		134,240
Other liabilities		122,007		100,182
Deferred tax liability		1,335		956
Income taxes payable		1,029		2,634
Total current liabilities		271,007		250,326
Other Liabilities:
Non-current other liabilities		4,468		3,676
Non-current government grants		1,500		1,470
Non-current income taxes payable		10,770		10,205
Non-current deferred tax liability		14,704		13,862
Shareholders' Equity:
Ordinary shares, par value 6 euro cents per share; 100,000,000 shares authorized,
60,436,120 shares issued and outstanding at June 30, 2011 and
60,247,092 shares issued and outstanding at December 31, 2010		5,079		5,063
Additional paid-in capital		203,658		196,960
Accumulated other comprehensive income		14,053		396
Retained earnings		489,010		467,580
Total Shareholders' Equity		711,800		669,999
Total Liabilities and Shareholders' Equity	$	1,014,249	$	949,538

The accompanying notes are an integral part of these condensed consolidated financial statements.

3

ICON plc

CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS

FOR THE THREE AND SIX MONTHS ENDED JUNE 30, 2011 AND JUNE 30, 2010

(UNAUDITED)

	Three Months Ended						Six Months Ended
	June 30,			June 30,			June 30,			June 30,
	2011			2010			2011			2010
	(in thousands except share and per share data)
Revenue:
Gross revenue	$	317,696		$	313,087		$	623,243		$	622,638
Reimbursable expenses		(84,651	)		(89,336	)		(160,901	)		(179,775	)
Net revenue		233,045			223,751			462,342			442,863
Costs and expenses:
Direct costs		150,866			130,869			295,336			262,187
Selling, general and administrative expense		57,344			58,923			117,227			111,217
Depreciation and amortization		9,329			8,281			18,302			17,003
Restructuring charges		-			-			5,002			-
Total costs and expenses		217,539			198,073			435,867			390,407
Income from operations		15,506			25,678			26,475			52,456
Interest income		294			405			527			640
Interest expense		(188	)		(344	)		(355	)		(771	)
Income before provision for income taxes		15,612			25,739			26,647			52,325
Provision for income taxes		(2,530	)		(2,866	)		(5,217	)		(7,253	)
Net income	$	13,082		$	22,873		$	21,430		$	45,072
Net income per Ordinary Share:
Basic	$	0.22		$	0.38		$	0.36		$	0.76
Diluted	$	0.21		$	0.38		$	0.35		$	0.74
Weighted average number of Ordinary Shares outstanding:
Basic		60,390,788			59,667,635			60,336,933			59,395,142
Diluted		61,114,996			60,768,374			61,056,232			60,557,687

The accompanying notes are an integral part of these condensed consolidated financial statements.

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ICON plc

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS

FOR THE SIX MONTHS ENDED JUNE 30, 2011 AND JUNE 30, 2010

(UNAUDITED)

	Six Months Ended
	June 30,			June 30,
	2011			2010
	(in thousands)
Cash flows from operating activities:
Net income		21,430			45,072
Adjustments to reconcile net income to net cash provided by operating activities:
Loss on disposal of property, plant and equipment		13			115
Depreciation and amortization		18,302			17,003
Amortization of grants		(59	)		(77	)
Share compensation expense		4,137			3,703
Deferred taxes		(2,296	)		(1,451	)
Changes in assets and liabilities:
Decrease in accounts receivable		3,949			19,195
(Increase)/decrease in unbilled revenue		(42,576	)		12,398
Increase in other receivables		(4,831	)		(243	)
Increase in prepayments and other current assets		(1,188	)		(3,662	)
Increase in other non current assets		(185	)		(626	)
Decrease in payments on account		(316	)		(20,784	)
Increase/(decrease) in other current liabilities		1,537			(8,527	)
(Decrease)/increase in other non current liabilities		(191	)		472
(Increase)/decrease in income taxes receivable		314			(6,661	)
Decrease in accounts payable		(9,699	)		(4,107	)
Net cash (used in)/provided by operating activities		(11,659	)		51,820
Cash flows from investing activities:
Purchase of property, plant and equipment		(13,097	)		(16,969	)
Purchase of subsidiary undertakings		(33,227	)		(1,161	)
Cash acquired with subsidiary undertakings		6,335			-
Purchase of short term investments		(40,000	)		(30,260	)
Sale of short term investments		-			79,487
Net cash (used in)/provided by investing activities		(79,989	)		31,097
Cash flows from financing activities:
Proceeds from exercise of share options		2,358			8,996
Share issuance costs		(66	)		(28	)
Tax benefit from the exercise of share options		285			2,179
Repayment of other liabilities		-			(160	)
Net cash provided by financing activities		2,577			10,987
Effect of exchange rate movements on cash		8,929			(17,943	)
Net (decrease)/increase in cash and cash equivalents		(80,142	)		75,961
Cash and cash equivalents at beginning of period		255,706			144,801
Cash and cash equivalents at end of period	$	175,564		$	220,762

The accompanying notes are an integral part of these condensed consolidated financial statements.

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ICON plc

CONDENSED CONSOLIDATED STATEMENTS OF SHAREHOLDERS' EQUITY AND COMPREHENSIVE INCOME

(UNAUDITED)

	Shares		Amount		Additional Paid-in Capital			Accumulated Other Comprehensive Income			Retained Earnings		Total
	(dollars in thousands, except share data)
Balance at December 31, 2010		60,247,092	$	5,063	$	196,960		$	396		$	467,580	$	669,999
Comprehensive Income:
Net income		-		-		-			-			21,430		21,430
Currency translation adjustment		-		-		-			15,824			-		15,824
Currency impact of long term funding		-		-		-			(1,921	)		-		(1,921	)
Tax on currency impact of long term funding		-		-		-			(246	)		-		(246	)
Total comprehensive income														35,087
Exercise of share options		185,260		16		2,342			-			-		2,358
Issue of ordinary shares		3,768		-		-			-			-		-
Share issuance costs		-		-		(66	)		-			-		(66	)
Non-cash stock compensation expense		-		-		4,137			-			-		4,137
Tax benefit on exercise of options		-		-		285			-			-		285
Balance at June 30, 2011		60,436,120	$	5,079	$	203,658		$	14,053		$	489,010	$	711,800

The accompanying notes are an integral part of these condensed consolidated financial statements.

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ICON plc

NOTES TO THE CONDENSED CONSOLIDATED FINANCIAL STATEMENTS

(UNAUDITED)

JUNE 30, 2011

1. Basis of Presentation

These condensed consolidated financial statements, which have been prepared in accordance with United States generally accepted accounting principles (“US GAAP”), have not been audited. The condensed consolidated financial statements reflect all adjustments, which are, in the opinion of management, necessary to present a fair statement of the operating results and financial position for the periods presented. The preparation of the condensed consolidated financial statements in conformity with US GAAP requires management to make estimates and assumptions that affect reported amounts and disclosures in the condensed consolidated financial statements. Actual results could differ from those estimates.

The condensed consolidated financial statements should be read in conjunction with the accounting policies and notes to the consolidated financial statements included in ICON’s Form 20-F for the year ended December 31, 2010. Operating results for the six months ended June 30, 2011 are not necessarily indicative of the results that may be expected for the fiscal period ending December 31, 2011.

2. Goodwill

	June 30,		December 31,
	2011		2010
	(in thousands)
Opening balance	$	175,860	$	173,568
Current period acquisitions		39,718		3,505
Prior period acquisitions		-		2,539
Foreign exchange movement		4,033		(3,752	)
Closing balance	$	219,611	$	175,860

The goodwill balance relates entirely to the clinical research segment.

Acquisition of Oxford Outcomes

On January 14, 2011 the Company acquired approximately 80% of the common stock of Oxford Outcomes Limited, a leading international health outcomes consultancy business, headquartered in Oxford, United Kingdom, and with offices in the USA and Canada, for an initial cash consideration of £17.8 million ($27.7 million).  Oxford Outcomes provides specialist services in the areas of patient reported outcomes (PRO), health economics, epidemiology and translation and linguistic validation.  Further consideration of up to £6.5 million ($10.4 million) may become payable during the period to March 31, 2012 if certain performance milestones are achieved.  The Company has accrued £6.5 million ($10.4 million) in respect of these milestones at June 30, 2011.  In addition, the acquisition agreement also provided for certain working capital targets to be achieved by Oxford Outcomes Limited on completion.  In May 2011 the Company paid an additional £3.3 million ($5.5 million) on completion of this review.

The Company also holds an option to acquire the remaining common stock of Oxford Outcomes Limited during the year ended December 31, 2011 for cash consideration of £3.8 million ($6.1 million).  Further consideration of up to £1.5 million ($2.4 million) relating to this remaining common stock of Oxford Outcomes may become payable during the period to March 31, 2012 if certain performance milestones are achieved.  £3.8 million ($6.1 million) has been accrued at June 30, 2011 in respect of additional consideration payable in respect of this option and a further £1.5 million ($2.4 million) has been accrued at June 30, 2011 relating to the potential additional consideration payable in respect of the performance milestones.

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The acquisition of Oxford Outcomes has been accounted for as a business combination in accordance with FASB ASC 805 Business Combinations. The following table summarizes the fair values of the assets acquired and the liabilities assumed:

	January 14
	2011
	(in thousands)
Property, plant and equipment	$	490
Goodwill		39,718
Cash and cash equivalents		6,335
Other current assets		6,679
Current liabilities		(1,995	)
Purchase price	$	51,227

Goodwill represents the acquisition of an established workforce with experience in the areas of patient reported outcomes (PRO), health economics, epidemiology and translation and linguistic validation.

Prior Period Acquisitions - Acquisition of Timaq Medical Imaging

On May 17, 2010 the Company acquired Timaq Medical Imaging (“Timaq”), a European provider of advanced imaging services to the pharmaceutical and biotechnology industry, located in Zurich, Switzerland for an initial cash consideration of CHF 1.3 million ($1.2 million).  Certain performance milestones were built into the acquisition agreement requiring potential additional consideration of up to CHF 2.9 million ($3.1 million) if these milestones are achieved during the years ended December 31, 2010 to December 31, 2013. On December 31, 2010 CHF 0.3 million ($0.3 million) was paid to the former shareholders in respect of certain milestones for the year ended December 31, 2010.  CHF 2.6 million ($2.9 million) has been accrued in relation to the remaining milestones at June 30, 2011.

The acquisition of Timaq has been accounted for as a business combination in accordance with FASB ASC 805 Business Combinations. The following table summarizes the fair values of the assets acquired and the liabilities assumed:

	May 17
	2010
	(in thousands)
Property, plant and equipment	$	107
Goodwill		3,505
Intangible assets		770
Other current assets		160
Current liabilities		(719	)
Purchase price	$	3,823

Goodwill represents the acquisition of an established workforce with experience in the provision of advanced imaging services to pharmaceutical and biotechnology customers in the European market.

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3. Restructuring charges

Restructuring charges recognized during the six months ended June 30, 2011 comprise:

		Six Months Ended
		June 30,		June 30,
		2011		2010
		(in thousands)
Restructuring charges	$	5,002	$	-

During the six months ended June 30, 2011 the Company commenced a review of its operations to improve resource utilization within the business and better align resources to current and future growth opportunities of the business.  This review resulted in the adoption of a restructuring plan, the closure of the Company’s facility in Edinburgh, United Kingdom and resource rationalizations in certain of the more mature markets in which it operates.  A restructuring charge of $5.0 million was recognized during the six months ended June 30, 2011, $1.0 million in respect of lease termination and exit costs associated with the closure of the Edinburgh facility and $4.0 million in respect of workforce reductions.

Details of the movement in restructuring provisions recognised during the six months ended June 30, 2011 are as follows:

	Workforce			Office
	Reductions			Consolidations			Total
	(in thousands)
Initial provision recognised	$	3,956		$	1,046		$	5,002
Cash payments		(2,491	)		(95	)		(2,586	)
P,P&E write-off		-			(29	)		(29	)
Foreign exchange movement		(1	)		(8	)		(9	)
Closing provision	$	1,464		$	914		$	2,378

4. Income Taxes

As at June 30, 2011 the Company maintains a $10.3 million liability (December 31, 2010: $9.7 million) for unrecognized tax benefit, which is comprised of $8.5 million (December 31, 2010: $8.1 million) related to items generating unrecognized tax benefits and $1.8 million (December 31, 2010: $1.8 million) for interest and related penalties to such items. The Company recognizes interest accrued on unrecognized tax benefits as an additional income tax expense.

The Company has analyzed filing positions in all of the significant federal, state and foreign jurisdictions where it is required to file income tax returns, as well as open tax years in these jurisdictions. The only periods subject to examination by the major tax jurisdictions where the Company does business are 2006 through 2010 tax years. The Company does not believe that the outcome of any examination will have a material impact on its financial statements.

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5. Net income per ordinary share

Basic net income per ordinary share has been computed by dividing net income available to ordinary shareholders by the weighted average number of ordinary shares outstanding during the period. Diluted net income per ordinary share is computed by adjusting the weighted average number of ordinary shares outstanding during the period for all potentially dilutive ordinary shares outstanding during the period and adjusting net income for any changes in income or loss that would result from the conversion of such potential ordinary shares. There is no difference in net income used for basic and diluted net income per ordinary share.

The reconciliation of the number of shares used in the computation of basic and diluted net income per ordinary share is as follows:

	Three Months Ended				Six Months Ended
	June 30,		June 30,		June 30,		June 30,
	2011		2010		2011		2010
Weighted average number of ordinary shares outstanding for basic net income per ordinary share		60,390,788		59,667,635		60,336,933		59,395,142
Effect of dilutive share options outstanding		724,208		1,100,739		719,299		1,162,545
Weighted average number of ordinary shares for diluted net income per ordinary share		61,114,996		60,768,374		61,056,232		60,557,687

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6. Stock Options

On July 21, 2008 the Company adopted the Employee Share Option Plan 2008 (the “2008 Employee Plan”) pursuant to which the Compensation and Organization Committee of the Company’s Board of Directors may grant options to any employee, or any director holding a salaried office or employment with the Company or a Subsidiary for the purchase of ordinary shares. On the same date, the Company also adopted the Consultants Share Option Plan 2008 (the “2008 Consultants Plan”), pursuant to which the Compensation and Organization Committee of the Company’s Board of Directors may grant options to any consultant, adviser or non-executive director retained by the Company or any Subsidiary for the purchase of ordinary shares.

Each option granted under the 2008 Employees Plan or the 2008 Consultants Plan (together the “2008 Option Plans”) will be an employee stock option, or NSO, as described in Section 422 or 423 of the Internal Revenue Code. Each grant of an option under the 2008 Options Plans will be evidenced by a Stock Option Agreement between the optionee and the Company. The exercise price will be specified in each Stock Option Agreement, however option prices will not be less than 100% of the fair market value of an ordinary share on the date the option is granted.

An aggregate of 6.0 million ordinary shares have been reserved under the 2008 Employee Plan as reduced by any shares issued or to be issued pursuant to options granted under the 2008 Consultants Plan, under which a limit of 400,000 shares applies.  Further, the maximum number of ordinary shares with respect to which options may be granted under the 2008 Employee Option Plan, during any calendar year to any employee shall be 400,000 ordinary shares.  There is no individual limit under the 2008 Consultants Option Plan.   No options may be granted under the plans after July 21, 2018.

On July 21, 2008 the Company adopted the 2008 Employees Restricted Share Unit Plan (the “2008 RSU Plan”) pursuant to which the Compensation and Organization Committee of the Company’s Board of Directors may select any employee, or any director holding a salaried office or employment with the Company or a Subsidiary to receive an award under the plan.  An aggregate of 1.0 million ordinary shares have been reserved for issuance under the 2008 RSU Plan.

On January 17, 2003 the Company adopted the Share Option Plan 2003 (the “2003 Plan”) pursuant to which the Compensation and Organization Committee of the Board may grant options to officers and other employees of the Company or its subsidiaries for the purchase of ordinary shares.  Each grant of an option under the 2003 Plan will be evidenced by a Stock Option Agreement between the employee and the Company. The exercise price will be specified in each Stock Option Agreement.

An aggregate of 6.0 million ordinary shares have been reserved under the 2003 Plan; and, in no event will the number of ordinary shares that may be issued pursuant to options awarded under the 2003 Plan exceed 10% of the outstanding shares, as defined in the 2003 Plan, at the time of the grant, unless the Board expressly determines otherwise. Further, the maximum number of ordinary shares with respect to which options may be granted under the 2003 Plan during any calendar year to any employee shall be 400,000 ordinary shares.  No options can be granted after January 17, 2013.

Share option awards are granted with an exercise price equal to the market price of the Company’s shares at date of grant.  Share options typically vest over a period of five years from date of grant and expire eight years from date of grant.  The maximum contractual term of options outstanding at June 30, 2011 is eight years.

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The following table summarizes option activity for the six months ended June 30, 2011:

	Options Outstanding Number of Shares			Weighted Average Exercise Price		Weighted Average Fair Value		Weighted Average Remaining Contractual Life
Outstanding at December 31, 2010		4,798,677		$	21.71	$	8.47
Granted		799,449		$	20.25	$	8.52
Exercised		(185,260	)	$	12.73	$	5.46
Forfeited		(254,900	)	$	26.41	$	10.05
Outstanding at June 30, 2011		5,157,966		$	21.57	$	8.51		4.89
Exercisable at June 30, 2011		2,642,124		$	19.48	$	7.77		3.51

The Company has granted options with fair values ranging from $3.68 to $13.93 per option or a weighted average fair value of $7.15 per option.  The Company issues ordinary shares for all options exercised. The total amount of fully vested share options which remained outstanding at June 30, 2011 was 2,642,124.  Fully vested share options at June 30, 2011 have an average remaining contractual term of 3.51 years, an average exercise price of $19.48 and a total intrinsic value of $17.1 million. The total intrinsic value of options exercised during the six months ended June 30, 2011 was $2.0 million (June 30, 2010: $14.9 million).

The following table summarizes the movement in non-vested share options for the six months ended June 30, 2011:

	Options Outstanding Number of Shares			Weighted Average Exercise Price		Weighted Average Fair Value
Non vested outstanding at December 31, 2010		2,673,674		$	24.76	$	9.48
Granted		799,449		$	20.25	$	8.52
Vested		(718,445	)	$	20.15	$	7.61
Forfeited		(238,836	)	$	25.52	$	9.79
Non vested outstanding at June 30, 2011		2,515,842		$	23.77	$	9.29

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Fair value of Stock Options Assumptions

The weighted average fair value of options granted during the period ended June 30, 2011 and June 30, 2010 was calculated using the Black-Scholes option pricing model.  The weighted average fair values and assumptions used were as follows:

	Three Months Ended
	June 30,		June 30,
	2011		2010
Weighted average fair value		$8.52		$9.13
Assumptions:
Expected volatility		45%		45%
Dividend yield		0%		0%
Risk-free interest rate		2.3%		1.8%
Expected life	5 years		4.05 years

Expected volatility is based on the historical volatility of our common stock over a period equal to the expected term of the options; the expected life represents the weighted average period of time that options granted are expected to be outstanding given consideration to vesting schedules, and our historical experience of past vesting and termination patterns. The risk-free rate is based on the U.S. government zero-coupon bonds yield curve in effect at time of the grant for periods corresponding with the expected life of the option.

Restricted Share Units

On February 10, 2011 the Company awarded 100,000 restricted share units (“RSU’s”) to certain key employees of the Group.  These RSU’s will vest on the fifth anniversary of date of award.  The market price of the Company’s ordinary shares on date of award was $22.11.  On March 3, 2011 the Company also awarded 120,000 RSU’s to other key employees of the Group.  These RSU’s will vest on the third anniversary of date of grant.  The market price of the Company’s ordinary shares on date of award was $20.28.  On June 7, 2011 the Company awarded a further 10,000 RSU’s to a key employee of the Group.  These RSU’s will vest on the third anniversary of date of grant.  The market price of the Company’s ordinary shares on date of award was $24.60.

On August 7, 2008 the Company awarded 6,280 RSU’s to certain key employees.  These RSU’s vested over periods ranging from February 26, 2009 to February 26, 2011.  The market value of the Company’s ordinary shares on date of award was $41.95.  On August 16, 2010 2,512 ordinary shares were issued by the Company relating to certain of the RSU awards.  On May 20, 2011 3,768 ordinary shares were issued by the Company relating to the remaining RSU awards.

The following table summarizes the movement in non-vested restricted share units for the six months ended June 30, 2011:

	Number of Units			Weighted Average Fair Value
Non vested outstanding at December 31, 2010		1,256		$	41.95
Granted		230,000		$	21.26
Vested		(1,256	)	$	41.95
Forfeited		-			-
Non vested outstanding at June 30, 2011		230,000		$	21.26

The fair value of stock awards vested for the six months ended June 30, 2011 totaled $0.1 million (2010: $0.1 million).

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Non-cash stock compensation expense

Non-cash stock compensation expense for the six months ended June 30, 2011 has been allocated to direct costs and selling, general and administrative expenses as follows:

	Three Months Ended				Six Months Ended
	June 30,		June 30,		June 30,		June 30,
	2011		2010		2011		2010
	(In thousands)				(In thousands)
Direct costs	$	1,209	$	1,017	$	2,280	$	2,007
Selling, general and administrative	$	985	$	888	$	1,857	$	1,696
	$	2,194	$	1,905	$	4,137	$	3,703

Total non-cash stock compensation expense not yet recognized at June 30, 2011 amounted to $17.2 million.  The weighted average period over which this is expected to be recognized is 3.2 years.  Total tax benefit recognized in additional paid in capital related to the non-cash compensation expense amounted to $0.3 million for the six months ended June 31, 2011 (2010: $1.0 million).

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7. Segment Information

The Company determines and presents operating segments based on the information that is internally provided to the Chief Executive Officer and Chief Financial Officer, who together are considered the Company’s chief operating decision maker, in accordance with FASB ASC 280-10 Disclosures about Segments of an Enterprises and Related Information.

The Company operates predominantly in the contract clinical research industry providing a broad range of clinical research and integrated product development services on a global basis for the pharmaceutical and biotechnology industries. Historically, the Company organized, operated and assessed its business in two segments, the clinical research segment and the central laboratory segment, which includes the Company’s central laboratories located in Dublin, New York, India, Singapore and China. During the year ended December 31, 2009 management determined that its clinical research and central laboratory businesses operate in the same clinical research market, have a similar customer profile, are subject to the same regulatory environment, support the development of new clinical therapies and are so economically similar, reporting their results on an aggregated basis would be more useful to users of the Company’s financial statements. In addition, the central laboratory division did not reach the thresholds of net revenue, income from operations and total assets as a requirement for being reported as a separate segment.  Accordingly, the Company consolidated and reclassified the results of the former central laboratory segment into the clinical research segment for the three and six months ended June 30, 2010.

During the year ended December 31, 2010 the Company incurred losses in its central laboratory business, which in accordance with FASB ASC 280-10 Disclosures about Segments of an Enterprises and Related Information requires it to be reported as a separate segment.  Accordingly the Company has disclosed two reportable segments for the three and six months ended June 30, 2011.  The Company has reclassified the results of the central laboratory segment from the clinical research segment for three and six months ended June 30, 2011.

The Company's areas of operation outside of Ireland principally include the United States, United Kingdom, France, Germany, Italy, Spain, The Netherlands, Sweden, Finland, Switzerland, Poland, Czech Republic, Lithuania, Latvia, Russia, Ukraine, Hungary, Israel, Romania, Canada, Mexico, Brazil, Colombia, Argentina, Chile, Peru, India, China, Hong Kong, South Korea, Japan, Thailand, Taiwan, Singapore, The Philippines, Australia, New Zealand, and South Africa. Segment information as at June 30, 2011 and December 31, 2010 and for the three and six months ended June 30, 2011 and June 30, 2010 is as follows:

a) The distribution of net revenue by geographical area was as follows:

	Three Months Ended				Six Months Ended
	June 30,		June 30,		June 30,		June 30,
	2011		2010		2011		2010
	(in thousands)				(in thousands)
Ireland	$	24,080	$	33,906	$	53,433	$	62,878
Rest of Europe		85,868		70,112		166,945		140,850
U.S.		93,826		96,876		186,390		194,331
Other		29,271		22,857		55,574		44,804
Total	$	233,045	$	223,751	$	462,342	$	442,863

    * All sales shown for Ireland are export sales.

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b)  The distribution of net revenue by business segment was as follows:

	Three Months Ended				Six Months Ended
	June 30,		June 30,		June 30,		June 30,
	2011		2010		2011		2010
	(in thousands)				(in thousands)
Clinical research	$	216,163	$	208,114	$	429,007	$	411,010
Central laboratory		16,882		15,637		33,335		31,853
Total	$	233,045	$	223,751	$	462,342	$	442,863

c)  The distribution of income from operations by geographical area was as follows:

	Three Months Ended					Six Months Ended
	June 30,			June 30,		June 30,			June 30,			June 30,			June 30,
	2011			2010		2011			2011			2011			2010
						Excluding Restructuring Charges			Restructuring Charges			Including Restructuring Charges
	(in thousands)					(in thousands)
Ireland	$	(4,386	)	$	13,526	$	(1,797	)		(85	)	$	(1,882	)	$	23,060
Rest of Europe		11,368			5,072		16,841			(1,803	)		15,038			12,931
U.S.		6,600			5,763		12,891			(3,114	)		9,777			13,432
Other		1,924			1,317		3,542			-			3,542			3,033
Total	$	15,506		$	25,678	$	31,477		$	(5,002	)	$	26,475		$	52,456

d)  The distribution of income from operations by business segment was as follows:

	Three Months Ended					Six Months Ended
	June 30,		June 30,			June 30,			June 30,			June 30,			June 30,
	2011		2010			2011			2011			2011			2010
						Excluding Restructuring Charges			Restructuring Charges			Including Restructuring Charges
	(in thousands)					(in thousands)
Clinical research	$	14,939	$	26,811		$	33,616			(3,457	)	$	30,159		$	53,531
Central laboratory		567		(1,133	)		(2,139	)		(1,545	)		(3,684	)		(1,075	)
Total	$	15,506	$	25,678		$	31,477		$	(5,002	)	$	26,475		$	52,456

e) The distribution of property, plant and equipment, net, by geographical area was as follows:

	June 30,		December 31,
	2011		2010
	(in thousands)
Ireland	$	115,118	$	109,919
Rest of Europe		18,664		16,675
U.S.		32,328		33,855
Other		9,022		10,412
Total	$	175,132	$	170,861

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f) The distribution of property, plant and equipment, net, by business segment was as follows:

	June 30,		December 31,
	2011		2010
	(in thousands)
Clinical research	$	154,252	$	149,755
Central laboratory		20,880		21,106
Total	$	175,132	$	170,861

g) The distribution of depreciation and amortization by geographical area was as follows:

	Three Months Ended				Six Months Ended
	June 30,		June 30,		June 30,		June 30,
	2011		2010		2011		2010
	(in thousands)				(in thousands)
Ireland	$	3,236	$	2,347	$	6,182	$	4,977
Rest of Europe		1,854		1,283		3,436		2,859
U.S.		3,125		3,647		6,468		7,215
Other		1,114		1,004		2,216		1,952
Total	$	9,329	$	8,281	$	18,302	$	17,003

h) The distribution of depreciation and amortization by business segment was as follows:

	Three Months Ended				Six Months Ended
	June 30,		June 30,		June 30,		June 30,
	2011		2010		2011		2010
	(in thousands)				(in thousands)
Clinical research	$	7,962	$	7,045	$	15,697	$	14,525
Central laboratory		1,367		1,236		2,605		2,478
Total	$	9,329	$	8,281	$	18,302	$	17,003

i) The distribution of total assets by geographical area was as follows:

	June 30,		December 31,
	2011		2010
	(in thousands)
Ireland	$	402,130	$	418,098
Rest of Europe		240,854		173,668
U.S.		338,662		329,971
Other		32,603		27,801
Total	$	1,014,249	$	949,538

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j) The distribution of total assets by business segment was as follows:

	June 30,		December 31,
	2011		2010
	(in thousands)
Clinical research	$	952,179	$	889,534
Central laboratory		62,070		60,004
Total	$	1,014,249	$	949,538

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ICON plc

Management’s Discussion and Analysis of Financial Condition and Results of Operations.

The following discussion and analysis should be read in conjunction with the unaudited Condensed Consolidated Financial Statements and accompanying notes included elsewhere herein and the Consolidated Financial Statements and related notes thereto included in our  Form 20-F for the year ended December 31, 2010. The Consolidated Financial Statements have been prepared in accordance with accounting principles generally accepted in the United States.

Overview

We are a contract research organization (“CRO”), providing outsourced development services on a global basis to the pharmaceutical, biotechnology and medical device industries. We specialize in the strategic development, management and analysis of programs that support Clinical Development - from compound selection to Phase I-IV clinical studies. We have the operational flexibility to provide development services on a stand-alone basis or as part of an integrated “full service” solution. Our preferred approach is to use dedicated teams to achieve optimum results, but we can implement a range of resourcing models to suit client requirements, and increasingly our teams are flexibly applied to minimize costs for our clients.

In a highly fragmented industry, we are one of a small number of companies with the capability and expertise to conduct clinical trials in all major therapeutic areas on a global basis. Currently, we have approximately 7,800 employees, in 77 locations in 39 countries, providing Phase I - IV Clinical Trial Management, Drug Development Support Services, Data Management, Biostatistics, Central Laboratory, Imaging and Contract Staffing services.

Revenue consists primarily of fees earned under contracts with third-party clients. In most cases, a portion of the contract fee is paid at the time the study or trial is started, with the balance of the contract fee generally payable in installments over the study or trial duration, based on the achievement of certain performance targets or "milestones". Revenue for contracts is recognized on a proportional performance method based on the relationship between time incurred and the total estimated duration of the trial or on a fee-for-service basis according to the particular circumstances of the contract. As is customary in the CRO industry, we contract with third party investigators in connection with clinical trials. All investigator fees and certain other costs, where reimbursed by clients, are, in accordance with industry practice, deducted from gross revenue to arrive at net revenue. As these costs vary from contract to contract, we view net revenue as our primary measure of revenue growth.

Our backlog consists of potential net revenue yet to be earned from projects awarded by clients. At June 30, 2011 we had a backlog of approximately $2.1 billion, compared with approximately $1.9 billion at December 31, 2010.  We believe that our backlog as of any date is not necessarily a meaningful predictor of future results, due to the potential for cancellation or delay of the projects underlying the backlog, and no assurances can be given that we will be able to realize this backlog as net revenue.

As the nature of ICON's business involves the management of projects having a typical duration of one to three years, the commencement or completion of projects in a fiscal year can have a material impact on revenues earned with the relevant clients in such years. In addition, as we typically work with some, but not all, divisions of a client, fluctuations in the number and status of available projects within such divisions can also have a material impact on revenues earned from such clients from year to year.

Although we are domiciled in Ireland, we report our results in U.S. dollars. As a consequence the results of our non-U.S. based operations, when translated into U.S. dollars, could be materially affected by fluctuations in exchange rates between the U.S. dollar and the currencies of those operations.

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In addition to translation exposures, we are also subject to transaction exposures because the currency in which contracts are priced can be different from the currencies in which costs relating to those contracts are incurred.  Our operations in the United States are not materially exposed to such currency differences as the majority of our revenues and costs are in U.S. dollars. However, outside the United States the multinational nature of our activities means that contracts are usually priced in a single currency, most often U.S. dollars, Euros or pounds Sterling, while costs arise in a number of currencies, depending, among other things, on which of our offices provide staff for the contract, and the location of investigator sites. Although many such contracts benefit from some degree of natural hedging due to the matching of contract revenues and costs in the same currency, where costs are incurred in currencies other than those in which contracts are priced, fluctuations in the relative value of those currencies could have a material effect on our results of operations. We regularly review our currency exposures and usually negotiate currency fluctuation clauses in our contracts which allow for price negotiation if changes in the relative value of those currencies exceed predetermined tolerances.

As we conduct operations on a global basis, our effective tax rate has depended and will depend on the geographic distribution of our revenue and earnings among locations with varying tax rates. Our results of operations therefore may be affected by changes in the tax rates of the various jurisdictions. In particular, as the geographic mix of our results of operations among various tax jurisdictions changes, our effective tax rate may vary significantly from period to period.

Results of Operations

Three Months Ended June 30, 2011 compared with Three Months Ended June 30, 2010

The following table sets forth for the periods indicated certain financial data as a percentage of net revenue and the percentage change in these items compared to the prior comparable period. The trends illustrated in the following table may not be indicative of future results.

	Three Months Ended
	June 30, 2011			June 30, 2010			2010 to 2011
							Percentage
	Percentage of Net Revenue						Increase/ (decrease)
Net revenue		100.0	%		100.0	%		4.2	%
Costs and expenses:
Direct costs		64.7	%		58.5	%		15.3	%
Selling, general and administrative		24.6	%		26.3	%		(2.7	)%
Depreciation and amortization		4.0	%		3.7	%		12.6	%
Income from operations		6.7	%		11.5	%		(39.6	)%

Net revenue for the period increased by $9.2 million, or 4.2%, from $223.8 million for the three months ended June 30, 2010 to $233.0 million for the three months ended June 30, 2011.  Net revenue in our clinical research segment increased by $8.1 million, or 3.9%, from $208.1 million for the three months ended June 30, 2010 to $216.2 million for the three months ended June 30, 2011.  In our central laboratory business, net revenue increased by $1.1 million, or 8.0%, from $15.7 million for the three months ended June 30, 2010 to $16.8 million for the three months ended June 30, 2011. For the three months ended June 30, 2011 we derived approximately 40.3%, 47.2% and 12.5% of our net revenue in the United States, Europe and Rest of World, respectively.

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Direct costs for the period increased by $20.0 million, or 15.3%, from $130.9 million for the three months ended June 30, 2010 to $150.9 million for the three months ended June 30, 2011. Direct costs consist primarily of compensation, associated fringe benefits and share based compensation expense for project-related employees and other direct project driven costs. Direct costs in our clinical research segment increased by $17.3 million, or 14.2%, from $121.4 million for the three months ended June 30, 2010 to $138.7 million for the three months ended June 30, 2011.  The Company has entered a number of strategic relationships with sponsors in recent months and further expanded operations in certain territories. This  necessitated the Company’s continued investment in personnel in advance of anticipated revenue flows from this business.  In our central laboratory business, direct costs increased by $2.7 million, or 28.5%, from $9.5 million for the three months ended June 30, 2010 to $12.2 million for the three months ended June 30, 2011. Increased business wins in this business over the previous twelve months has also necessitated significant upfront investment in personnel and related costs to serve this new business.  Direct costs as a percentage of net revenue increased to 64.7% for the three months ended June 30, 2011 from 58.5% for the three months ended June 30, 2010.

Selling, general and administrative expenses for the period decreased by $1.6 million, or 2.7%, from $58.9 million for the three months ended June 30, 2010 to $57.3 million for the three months ended June 30, 2011. Selling, general and administrative expenses comprise compensation, related fringe benefits and share based compensation expense for selling and administrative employees, professional service costs, advertising costs and all costs related to facilities and information systems. The decrease in selling, general and administrative expense for the period arose primarily from an increase in facilities and information costs of $3.5 million, an increase in compensation and related fringe benefit costs for non project-related employees of $1.5 million offset by a decrease in other general overhead costs of $6.6 million.  This decrease in other general overhead costs resulted principally from the release of certain non-recurring tax related provisions in both our clinical research and central laboratory businesses arising from the receipt of additional information in relation to these items.  As a percentage of net revenue, selling, general and administrative expenses, decreased from 26.3% for the three months ended June 30, 2010 to 24.6% for the three months ended June 30, 2011.

Depreciation and amortization expense for the period increased by $1.0 million, or 12.6%, from $8.3 million for the period ended June 30, 2010 to $9.3 million for the three months ended June 30, 2011. As a percentage of net revenue, depreciation and amortization expense increased from 3.7% of net revenues for the three months ended June 30, 2010 to 4.0% for the three months ended June 30, 2011.

As a result of the above, income from operations for the period decreased by $10.2 million, from $25.7 million for the three months ended June 30, 2010 to $15.5 million for the three months ended June 30, 2011. As a percentage of net revenue, income from operations decreased from 11.5% for the three months ended June 30, 2010 to 6.7% for the three months ended June 30, 2011. In our clinical research segment, income from operations as a percentage of net revenue decreased from 11.5% for the year ended June 30, 2011 to 6.4% for the three months ended June 30, 2011, a result of our continued investment in personnel in this business. In our central laboratory business, income/(loss) from operations increased from (0.5)% for the three months ended June 30, 2010 to a 0.2% for the three months ended June 30, 2011.  The decrease in losses in our central laboratory business during the three months ended June 30, 2011 has resulted principally from the release of certain non-recurring tax related provisions during the period.

Interest expense for the period decreased from $0.4 million for the three months ended June 30, 2011 to $0.3 million for the three months ended June 30, 2011.  This decrease arose from reduced commitment fees payable on negotiated facilities, arising from the reduction in amounts available to draw under such facilities over the period since June 30, 2010. Interest income for the three months ended June 30, 2011 decreased from $0.3 million for the three months ended June 30, 2010 to $0.2 million for the three months ended June 30, 2011.

Provision for income taxes for the period decreased from $2.9 million for the three months ended June 30, 2010 to $2.5 million for the three months ended June 30, 2011.  The effective tax rate for the three months ended June 30, 2011 was 16.2% compared with 11.1% for the three months ended June 30, 2010. The Company’s effective tax rate is principally a function of the distribution of pre-tax profits amongst the territories in which it operates.

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Six Months Ended June 30, 2011 compared with Six Months Ended June 30, 2010

The following table sets forth for the periods indicated certain financial data as a percentage of net revenue and the percentage change in these items compared to the prior comparable period. The trends illustrated in the following table may not be indicative of future results.

	Six Months Ended
	June 30, 2011			June 30, 2010			2010 to 2011
							Percentage
	Percentage of Net Revenue						Increase/ (decrease)
Net revenue		100.0	%		100.0	%		4.4	%
Costs and expenses:
Direct costs		63.9	%		59.2	%		12.6	%
Selling, general and administrative		25.3	%		25.1	%		5.4	%
Depreciation and amortization		4.0	%		3.9	%		7.6	%
One-time net charges		1.1	%		0.0	%		100.0	%
Income from operations		5.7	%		11.8	%		(49.5	)%

Net revenue for the period increased by $19.5 million, or 4.4%, from $442.9 million for the six months ended June 30, 2010 to $462.3 million for the six months ended June 30, 2010. Net revenue in our clinical research segment increased by $18.0 million, or 4.4%, from $411.0 million for the six months ended June 30, 2010 to $429.0 million for the six months ended June, 2011. In our central laboratory business, net revenue increased by $1.4 million, or 4.7%, from $31.9 million for the six months ended June 30, 2010 to $33.3 million for the six months ended June 30, 2011. For the six months ended June 30, 2011 we derived approximately 40.3%, 47.7% and 12.0% of our net revenue in the United States, Europe and Rest of World, respectively.

Direct costs for the period increased by $33.1 million, or 12.6%, from $262.2 million for the six months ended June 30, 2010 to $295.3 million for the six months ended June 30, 2011. Direct costs consist primarily of compensation, associated fringe benefits and share based compensation expense for project-related employees and other direct project driven costs.  Direct costs in our clinical research segment increased by $27.9 million, or 11.5%, from $243.1 million for the six months ended June 30, 2010 to $271.0 million for the six months ended June 30, 2011. The Company has entered a number of strategic relationships with sponsors in recent months and further expanded operations in certain territories. This has necessitated the Company’s continued investment in personnel in advance of anticipated revenue flows from this business.  In our central laboratory business, direct costs increased by $5.2 million, or 27.4%, from $19.1 million for the six months ended June 30, 2010 to $24.3 million for the six months ended June 30, 2011. Increased business wins in this business over the previous twelve months has also necessitated significant upfront investment in personnel and related costs to serve this new business.  Direct costs as a percentage of net revenue increased from 59.2% for the six months ended June 30, 2010 to 63.9% for the six months ended June 30, 2011.

Selling, general and administrative expenses for the period increased by $6.0 million, or 5.4%, from $111.2 million for the six months ended June 30, 2010 to $117.2 million for the six months ended June 30, 2011. Selling, general and administrative expenses consist of compensation, related fringe benefits and share based compensation expense for selling and administrative employees, professional service costs, advertising costs and all costs related to facilities and information systems. The increase in selling, general and administrative expense for the period arose primarily from an increase in facilities and information costs of $5.8 million, an increase in foreign exchange losses on the retranslation of monetary assets and liabilities of $1.0 million, offset by a reduction in general overhead costs of $0.7 million.  As a percentage of net revenue, selling, general and administrative expenses, increased from 25.1% for the six months ended June 30, 2010 to 25.3% for the six months ended June 30, 2011.

Depreciation and amortization expense for the period increased by $1.3 million, or 7.6%, from $17.0 million for the six months ended June 30, 2010 to $18.3 million for the six months ended June 30, 2011. As a percentage of net revenue, depreciation and amortization expense increased from 3.9% of net revenues for the six months ended June 30, 2010 to 4.0% for the six months ended June 30, 2011.

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During the six months ended June 30, 2011 the Company commenced a review of its operations to improve resource utilization within the business and better align resources to current and future growth opportunities of the business.  This review resulted in the adoption of a restructuring plan, the closure of the Company’s facility in Edinburgh, United Kingdom and resource rationalizations in certain of the more mature markets in which it operates.  A restructuring charge of $5.0 million was recognized during the six months ended June 30, 2011 $1.0 million in respect of lease termination and exit costs associated with the closure of the Edinburgh facility and $4.0 million in respect of workforce reductions.

As a result of the above, income from operations for the period decreased by $26.0 million, from $52.5 million for the six months ended June 30, 2010 to $26.5 million for the six months ended June 30, 2011.  As a percentage of net revenue, income from operations decreased from 11.8% for the six months ended June 30, 2010 to 5.7% for the six months ended June 31, 2011. In our clinical research segment, income from operations as a percentage of net revenue decreased from 13.0% for the six months ended June 30, 2010 to 7.0% for the six months ended June 30, 2011.  In our central laboratory business, income/(loss) from operations increased from (3.4)% for the six months ended June 30, 2010 to (11.1)% for the six months ended June 30, 2011.

Excluding the impact of restructuring charges recognized during the six months ended June 30, 2011 income from operations decreased by $21.0 million, from $52.5 million for the six months ended June 30, 2010 to $31.5 million for the six months ended June 30, 2011. As a percentage of net revenue, income from operations excluding restructuring costs decreased from 11.8% for the six months ended June 30, 2010 to 6.8% for the six months ended June 30, 2011. In our clinical research segment, income from operations excluding restructuring costs, as a percentage of net revenue decreased from 13.0% for the six months ended June 30, 2010 to 7.8% for the six months ended June 30, 2011, a result of our continued investment in personnel in this business. In our central laboratory business, income/(loss) from operations excluding restructuring charges decreased from (3.4)% for the six months ended June 30, 2010 to (6.4)% for the six months ended June 30, 2011.

Interest expense for the period decreased from $0.8 million for the six months ended June 30, 2010 to $0.4 million for the six months ended June 30, 2011.  This decrease arose from reduced commitment fees payable on negotiated facilities, arising from the reduction in amounts available to draw under such facilities over the period since June 30, 2010. Interest income for the period decreased from $0.6 million for the six months ended June 30, 2010 to $0.5 million for the six months ended June 30, 2011.

Provision for income taxes for the period decreased from $7.3 million for the six months ended June 30, 2010 to $5.2 million for the six months ended June 30, 2011.  The effective tax rate for the six months ended June 30, 2011 was 19.6% compared with 13.9% for the six months ended June 30, 2010. The Company’s effective tax rate is principally a function of the distribution of pre-tax profits amongst the territories in which it operates.

Liquidity and Capital Resources

The CRO industry is generally not capital intensive. The Group’s principal operating cash needs are payment of salaries, office rents, travel expenditures and payments to investigators. Investing activities primarily reflect capital expenditures for facilities, information systems enhancements, the purchase of short term investments and acquisitions.

Our clinical research and development contracts are generally fixed price with some variable components and range in duration from a few weeks to several years. Revenue from contracts is generally recognized as income on the basis of the relationship between time incurred and the total estimated contract duration or on a fee-for-service basis. The cash flow from contracts typically consists of a down payment of between 10% and 20% paid at the time the contract is entered into, with the balance paid in installments over the contract's duration, in some cases on the achievement of certain milestones. Accordingly, cash receipts do not correspond to costs incurred and revenue recognized on contracts.

The Company’s cash balances at June 30, 2011 amounted to $215.6 million compared with cash balances of $255.7 million at December 31, 2010.  The Company’s cash balances at June 30, 2011 comprised cash and cash equivalents $175.6 million and short-term investments $40.0 million.  The Company’s cash balances at December 31, 2010 comprised cash and cash equivalents $255.7 million.  Additional amounts available to the Group under negotiated facilities amounted to $51.1 million at June 30, 2011 compared with additional amounts of $55.9 million at December 31, 2010.

23

Net cash used in operating activities was $11.7 million for the six months ended June 30, 2011 compared with cash provided by operating activities of $51.8 million for the six months ended June 30, 2010.  The most significant influence on our operating cash flow is revenue outstanding, which comprises accounts receivable and unbilled revenue, less payments on account. The dollar values of these amounts and the related days revenue outstanding can vary due to the achievement of contractual milestones, including contract signing, and the timing of cash receipts.  The decrease in cash flow from operating activities during the six months ended June 30, 2011 arose primarily from a decrease in net income together with an increase in the number of days revenue outstanding during the period.  The number of days revenue outstanding at June 30, 2011 was 49 days compared to 37 days at December 31, 2010.

Net cash used in investing activities was $80.0 million for the six months ended June 30, 2011 compared to net cash provided by investing activities of $31.1 million for the six months ended June 30, 2010. Net cash used in the six months ended June 30, 2011 arose primarily from cash paid for acquisitions, capital expenditures and the purchase of short-term investments.

During the six months ended June 30, 2011 the Company completed the acquisition of Oxford Outcomes Limited for an initial cash consideration of $27.7 million.  Further consideration $5.5 million was also paid in respect of certain working capital targets on completion.  These amounts were offset by cash received on the acquisition of $6.3 million.  Capital expenditure for the six months ended June 30, 2011 amounted to $13.1 million, and comprised mainly of expenditure on global infrastructure and information technology systems to support the Company’s growth.  During the six months ended June 30, 2011 the Company invested $40.0 million in short-term investments.  Net cash provided by investing activities in the six months ended June 30, 2010 arose principally from the sale of short term investments. During the six months ended June 30, 2010 the Company realized a net $49.2 million from the sale of its short term investments. Amounts realized from the sale of short term investments during the six months ended June 30, 2010 were reinvested in cash equivalents.  Capital expenditure for the six months ended June 30, 2010 amounted to $17.0 million.

Net cash provided by financing activities during the six months ended June 30, 2011 amounted to $2.6 million compared with net cash provided by financing activities of $11.0 million for the six months ended June 30, 2010. Net cash provided by financing activities in both periods arose primarily from the exercise of stock options.

As a result of these cash flows, cash and cash equivalents decreased by $80.1 million for the six months ended June 30, 2011 compared to an increase of $76.0 million for the six months ended June 30, 2010.

On July 9, 2007 the Company entered into a five year committed multi-currency facility agreement for €35 million ($49.7 million) with Bank of Ireland.  The facility bears interest at an annual rate equal to EURIBOR plus a margin and is secured by certain composite guarantees, indemnities and pledges in favor of the bank.  Amounts available to be drawn reduce over the life of this facility in accordance with agreed payment terms.  At June 30, 2011 €13.1 million ($18.6 million) was available to be drawn under this facility.

On December 22, 2008 a committed three year US dollar credit facility was negotiated with Allied Irish Bank plc for $50 million. On April 21, 2010 the Company reduced this facility to $25 million.  On December 9, 2010 the Company further reduced this facility to $12.5 million. The facility bears interest at LIBOR plus a margin and is secured by certain composite guarantees and pledges in favor of the bank.  At June 30, 2011 $12.5 million was available to be drawn under this facility.

On May 29, 2009 a three year committed credit facility was negotiated with Citibank Europe for $10 million.  The facility bears interest at LIBOR plus a margin and is secured by certain composite guarantees and pledges in favor of the bank.  At June 30, 2011 $10.0 million was available to be drawn under the facility.

On May 29, 2009 a committed 364 day credit facility of $30 million was negotiated with JP Morgan for $30 million. On September 3, 2010 a committed 364 day credit facility was negotiated with J.P. Morgan for $10 million, partially replacing the 2009 facility.  The facility bears interest at LIBOR plus a margin and is secured by certain composite guarantees and pledges in favor of the bank.  At June 30, 2011 $10.0 million was available to be drawn under the facility.

24

On May 17, 2010 the Company acquired Timaq Medical Imaging, a European provider of advanced imaging services to the pharmaceutical and biotechnology industry, located in Zurich, Switzerland for an initial cash consideration of CHF 1.3 million ($1.2 million).  Certain performance milestones were built into the acquisition agreement requiring potential additional consideration of up to CHF 2.9 million ($3.1 million) if these milestones are achieved during the years ended December 31, 2010 to December 31, 2013. On December 31, 2010 CHF 0.3 million ($0.3 million) was paid to the former shareholders in respect of certain milestones for the year ended December 31, 2010.  CHF 2.6 million ($3.1 million) has been accrued in relation to the remaining milestones at June 30, 2011.

On January 14, 2011 the Company acquired approximately 80% of the common stock of Oxford Outcomes Limited, a leading international health outcomes consultancy business, headquartered in Oxford, United Kingdom, and with offices in the USA and Canada, for an initial cash consideration of £17.8 million ($27.7 million).  Oxford Outcomes provides specialist services in the areas of patient reported outcomes (PRO), health economics, epidemiology and translation and linguistic validation.  Further consideration of up to £6.5 million ($10.4 million) may become payable during the period to March 31, 2012 if certain performance milestones are achieved.  In addition, the acquisition agreement also provided for certain working capital targets to be achieved by Oxford Outcomes Limited on completion.  In May 2011 the Company paid an additional £3.3 million ($5.5 million) on completion of this review.

The Company also holds an option to acquire the remaining common stock of Oxford Outcomes Limited during the year ended December 31, 2011 for cash consideration of £3.8 million ($6.1 million).  Further consideration of up to £1.5 million ($2.4 million) relating to this remaining common stock of Oxford Outcomes may become payable during the period to March 31, 2012 if certain performance milestones are achieved.  £3.8 million ($6.1 million) has been accrued at June 30, 2011 in respect of additional consideration payable in respect of this option and a further £1.5 million ($2.4 million) has been accrued at June 30, 2011 relating to the potential additional consideration payable in respect of the performance milestones.

Inflation

We believe the effects of inflation generally do not have a material adverse impact on our operations or financial conditions.

Legal Proceedings

We are not party to any litigation or other legal proceedings that we believe could reasonably be expected to have a material adverse effect on our business, results of operations and financial condition.

25

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

	ICON plc
____________________________	/s/ Ciaran Murray
Date:  July 22, 2011	Ciaran Murray
	Chief Financial Officer

26

XML



Document and Entity Information	6 Months Ended
	Jun. 30, 2011
Document Information [Line Items]
Document Type	6-K
Amendment Flag	false
Document Period End Date	Jun. 30, 2011
Document Fiscal Year Focus	2011
Document Fiscal Period Focus	Q2
Trading Symbol	ICLR
Entity Registrant Name	ICON PLC /ADR/
Entity Central Index Key	0001060955
Current Fiscal Year End Date	--12-31

XML



Income Taxes

6 Months Ended

Jun. 30, 2011

Income Taxes

4. Income Taxes

As at June 30, 2011 the Company maintains a $10.3 million liability (December 31, 2010: $9.7 million) for unrecognized tax benefit, which is comprised of $8.5 million (December 31, 2010: $8.1 million) related to items generating unrecognized tax benefits and $1.8 million (December 31, 2010: $1.8 million) for interest and related penalties to such items. The Company recognizes interest accrued on unrecognized tax benefits as an additional income tax expense.

The Company has analyzed filing positions in all of the significant federal, state and foreign jurisdictions where it is required to file income tax returns, as well as open tax years in these jurisdictions. The only periods subject to examination by the major tax jurisdictions where the Company does business are 2006 through 2010 tax years. The Company does not believe that the outcome of any examination will have a material impact on its financial statements.

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Net income per ordinary share

6 Months Ended

Jun. 30, 2011

Net income per ordinary share

5. Net income per ordinary share

Basic net income per ordinary share has been computed by dividing net income available to ordinary shareholders by the weighted average number of ordinary shares outstanding during the period. Diluted net income per ordinary share is computed by adjusting the weighted average number of ordinary shares outstanding during the period for all potentially dilutive ordinary shares outstanding during the period and adjusting net income for any changes in income or loss that would result from the conversion of such potential ordinary shares. There is no difference in net income used for basic and diluted net income per ordinary share.

The reconciliation of the number of shares used in the computation of basic and diluted net income per ordinary share is as follows:

	Three Months Ended				Six Months Ended
	June 30,		June 30,		June 30,		June 30,
	2011		2010		2011		2010
Weighted average number of ordinary shares outstanding for basic net income per ordinary share		60,390,788		59,667,635		60,336,933		59,395,142
Effect of dilutive share options outstanding		724,208		1,100,739		719,299		1,162,545
Weighted average number of ordinary shares for diluted net income per ordinary share		61,114,996		60,768,374		61,056,232		60,557,687

XML



Stock Options

6 Months Ended

Jun. 30, 2011

Stock Options

6. Stock Options

On July 21, 2008 the Company adopted the Employee Share Option Plan 2008 (the “2008 Employee Plan”) pursuant to which the Compensation and Organization Committee of the Company’s Board of Directors may grant options to any employee, or any director holding a salaried office or employment with the Company or a Subsidiary for the purchase of ordinary shares. On the same date, the Company also adopted the Consultants Share Option Plan 2008 (the “2008 Consultants Plan”), pursuant to which the Compensation and Organization Committee of the Company’s Board of Directors may grant options to any consultant, adviser or non-executive director retained by the Company or any Subsidiary for the purchase of ordinary shares.

Each option granted under the 2008 Employees Plan or the 2008 Consultants Plan (together the “2008 Option Plans”) will be an employee stock option, or NSO, as described in Section 422 or 423 of the Internal Revenue Code. Each grant of an option under the 2008 Options Plans will be evidenced by a Stock Option Agreement between the optionee and the Company. The exercise price will be specified in each Stock Option Agreement, however option prices will not be less than 100% of the fair market value of an ordinary share on the date the option is granted.

An aggregate of 6.0 million ordinary shares have been reserved under the 2008 Employee Plan as reduced by any shares issued or to be issued pursuant to options granted under the 2008 Consultants Plan, under which a limit of 400,000 shares applies.  Further, the maximum number of ordinary shares with respect to which options may be granted under the 2008 Employee Option Plan, during any calendar year to any employee shall be 400,000 ordinary shares.  There is no individual limit under the 2008 Consultants Option Plan.   No options may be granted under the plans after July 21, 2018.

On July 21, 2008 the Company adopted the 2008 Employees Restricted Share Unit Plan (the “2008 RSU Plan”) pursuant to which the Compensation and Organization Committee of the Company’s Board of Directors may select any employee, or any director holding a salaried office or employment with the Company or a Subsidiary to receive an award under the plan.  An aggregate of 1.0 million ordinary shares have been reserved for issuance under the 2008 RSU Plan.

On January 17, 2003 the Company adopted the Share Option Plan 2003 (the “2003 Plan”) pursuant to which the Compensation and Organization Committee of the Board may grant options to officers and other employees of the Company or its subsidiaries for the purchase of ordinary shares.  Each grant of an option under the 2003 Plan will be evidenced by a Stock Option Agreement between the employee and the Company. The exercise price will be specified in each Stock Option Agreement.

An aggregate of 6.0 million ordinary shares have been reserved under the 2003 Plan; and, in no event will the number of ordinary shares that may be issued pursuant to options awarded under the 2003 Plan exceed 10% of the outstanding shares, as defined in the 2003 Plan, at the time of the grant, unless the Board expressly determines otherwise. Further, the maximum number of ordinary shares with respect to which options may be granted under the 2003 Plan during any calendar year to any employee shall be 400,000 ordinary shares.  No options can be granted after January 17, 2013.

Share option awards are granted with an exercise price equal to the market price of the Company’s shares at date of grant.  Share options typically vest over a period of five years from date of grant and expire eight years from date of grant.  The maximum contractual term of options outstanding at June 30, 2011 is eight years.

The following table summarizes option activity for the six months ended June 30, 2011:

	Options Outstanding Number of Shares			Weighted Average Exercise Price		Weighted Average Fair Value		Weighted Average Remaining Contractual Life
Outstanding at December 31, 2010		4,798,677		$	21.71	$	8.47
Granted		799,449		$	20.25	$	8.52
Exercised		(185,260	)	$	12.73	$	5.46
Forfeited		(254,900	)	$	26.41	$	10.05
Outstanding at June 30, 2011		5,157,966		$	21.57	$	8.51		4.89
Exercisable at June 30, 2011		2,642,124		$	19.48	$	7.77		3.51

The Company has granted options with fair values ranging from $3.68 to $13.93 per option or a weighted average fair value of $7.15 per option.  The Company issues ordinary shares for all options exercised. The total amount of fully vested share options which remained outstanding at June 30, 2011 was 2,642,124.  Fully vested share options at June 30, 2011 have an average remaining contractual term of 3.51 years, an average exercise price of $19.48 and a total intrinsic value of $17.1 million. The total intrinsic value of options exercised during the six months ended June 30, 2011 was $2.0 million (June 30, 2010: $14.9 million).

The following table summarizes the movement in non-vested share options for the six months ended June 30, 2011:

	Options Outstanding Number of Shares			Weighted Average Exercise Price		Weighted Average Fair Value
Non vested outstanding at December 31, 2010		2,673,674		$	24.76	$	9.48
Granted		799,449		$	20.25	$	8.52
Vested		(718,445	)	$	20.15	$	7.61
Forfeited		(238,836	)	$	25.52	$	9.79
Non vested outstanding at June 30, 2011		2,515,842		$	23.77	$	9.29

Fair value of Stock Options Assumptions

The weighted average fair value of options granted during the period ended June 30, 2011 and June 30, 2010 was calculated using the Black-Scholes option pricing model.  The weighted average fair values and assumptions used were as follows:

	Three Months Ended
	June 30,			June 30,
	2011			2010
Weighted average fair value	$	8.52		$	9.13
Assumptions:
Expected volatility		45	%		45	%
Dividend yield		0	%		0	%
Risk-free interest rate		2.3	%		1.8	%
Expected life	5 years			4.05 years

Expected volatility is based on the historical volatility of our common stock over a period equal to the expected term of the options; the expected life represents the weighted average period of time that options granted are expected to be outstanding given consideration to vesting schedules, and our historical experience of past vesting and termination patterns. The risk-free rate is based on the U.S. government zero-coupon bonds yield curve in effect at time of the grant for periods corresponding with the expected life of the option.

Restricted Share Units

On February 10, 2011 the Company awarded 100,000 restricted share units (“RSU’s”) to certain key employees of the Group.  These RSU’s will vest on the fifth anniversary of date of award.  The market price of the Company’s ordinary shares on date of award was $22.11.  On March 3, 2011 the Company also awarded 120,000 RSU’s to other key employees of the Group.  These RSU’s will vest on the third anniversary of date of grant.  The market price of the Company’s ordinary shares on date of award was $20.28.  On June 7, 2011 the Company awarded a further 10,000 RSU’s to a key employee of the Group.  These RSU’s will vest on the third anniversary of date of grant.  The market price of the Company’s ordinary shares on date of award was $24.60.

On August 7, 2008 the Company awarded 6,280 RSU’s to certain key employees.  These RSU’s vested over periods ranging from February 26, 2009 to February 26, 2011.  The market value of the Company’s ordinary shares on date of award was $41.95.  On August 16, 2010 2,512 ordinary shares were issued by the Company relating to certain of the RSU awards.  On May 20, 2011 3,768 ordinary shares were issued by the Company relating to the remaining RSU awards.

The following table summarizes the movement in non-vested restricted share units for the six months ended June 30, 2011:

	Number of Units			Weighted Average Fair Value
Non vested outstanding at December 31, 2010		1,256		$	41.95
Granted		230,000		$	21.26
Vested		(1,256	)	$	41.95
Forfeited		-			-
Non vested outstanding at June 30, 2011		230,000		$	21.26

The fair value of stock awards vested for the six months ended June 30, 2011 totaled $0.1 million (2010: $0.1 million).

Non-cash stock compensation expense

Non-cash stock compensation expense for the six months ended June 30, 2011 has been allocated to direct costs and selling, general and administrative expenses as follows:

	Three Months Ended				Six Months Ended
	June 30,		June 30,		June 30,		June 30,
	2011		2010		2011		2010
	(In thousands)				(In thousands)
Direct costs	$	1,209	$	1,017	$	2,280	$	2,007
Selling, general and administrative	$	985	$	888	$	1,857	$	1,696
	$	2,194	$	1,905	$	4,137	$	3,703

Total non-cash stock compensation expense not yet recognized at June 30, 2011 amounted to $17.2 million.  The weighted average period over which this is expected to be recognized is 3.2 years.  Total tax benefit recognized in additional paid in capital related to the non-cash compensation expense amounted to $0.3 million for the six months ended June 31, 2011 (2010: $1.0 million).

XML



Segment Information

6 Months Ended

Jun. 30, 2011

Segment Information

7. Segment Information

The Company determines and presents operating segments based on the information that is internally provided to the Chief Executive Officer and Chief Financial Officer, who together are considered the Company’s chief operating decision maker, in accordance with FASB ASC 280-10 Disclosures about Segments of an Enterprises and Related Information.

The Company operates predominantly in the contract clinical research industry providing a broad range of clinical research and integrated product development services on a global basis for the pharmaceutical and biotechnology industries. Historically, the Company organized, operated and assessed its business in two segments, the clinical research segment and the central laboratory segment, which includes the Company’s central laboratories located in Dublin, New York, India, Singapore and China. During the year ended December 31, 2009 management determined that its clinical research and central laboratory businesses operate in the same clinical research market, have a similar customer profile, are subject to the same regulatory environment, support the development of new clinical therapies and are so economically similar, reporting their results on an aggregated basis would be more useful to users of the Company’s financial statements. In addition, the central laboratory division did not reach the thresholds of net revenue, income from operations and total assets as a requirement for being reported as a separate segment.  Accordingly, the Company consolidated and reclassified the results of the former central laboratory segment into the clinical research segment for the three and six months ended June 30, 2010.

During the year ended December 31, 2010 the Company incurred losses in its central laboratory business, which in accordance with FASB ASC 280-10 Disclosures about Segments of an Enterprises and Related Information requires it to be reported as a separate segment.  Accordingly the Company has disclosed two reportable segments for the three and six months ended June 30, 2011.  The Company has reclassified the results of the central laboratory segment from the clinical research segment for three and six months ended June 30, 2011.

The Company's areas of operation outside of Ireland principally include the United States, United Kingdom, France, Germany, Italy, Spain, The Netherlands, Sweden, Finland, Switzerland, Poland, Czech Republic, Lithuania, Latvia, Russia, Ukraine, Hungary, Israel, Romania, Canada, Mexico, Brazil, Colombia, Argentina, Chile, Peru, India, China, Hong Kong, South Korea, Japan, Thailand, Taiwan, Singapore, The Philippines, Australia, New Zealand, and South Africa. Segment information as at June 30, 2011 and December 31, 2010 and for the three and six months ended June 30, 2011 and June 30, 2010 is as follows:

a) The distribution of net revenue by geographical area was as follows:

	Three Months Ended				Six Months Ended
	June 30,		June 30,		June 30,		June 30,
	2011		2010		2011		2010
	(in thousands)				(in thousands)
Ireland	$	24,080	$	33,906	$	53,433	$	62,878
Rest of Europe		85,868		70,112		166,945		140,850
U.S.		93,826		96,876		186,390		194,331
Other		29,271		22,857		55,574		44,804
Total	$	233,045	$	223,751	$	462,342	$	442,863

    * All sales shown for Ireland are export sales.

b)  The distribution of net revenue by business segment was as follows:

	Three Months Ended				Six Months Ended
	June 30,		June 30,		June 30,		June 30,
	2011		2010		2011		2010
	(in thousands)				(in thousands)
Clinical research	$	216,163	$	208,114	$	429,007	$	411,010
Central laboratory		16,882		15,637		33,335		31,853
Total	$	233,045	$	223,751	$	462,342	$	442,863

c)  The distribution of income from operations by geographical area was as follows:

	Three Months Ended					Six Months Ended
	June 30,			June 30,		June 30,			June 30,			June 30,			June 30,
	2011			2010		2011			2011			2011			2010
						Excluding Restructuring Charges			Restructuring Charges			Including Restructuring Charges
	(in thousands)					(in thousands)
Ireland	$	(4,386	)	$	13,526	$	(1,797	)		(85	)	$	(1,882	)	$	23,060
Rest of Europe		11,368			5,072		16,841			(1,803	)		15,038			12,931
U.S.		6,600			5,763		12,891			(3,114	)		9,777			13,432
Other		1,924			1,317		3,542			-			3,542			3,033
Total	$	15,506		$	25,678	$	31,477		$	(5,002	)	$	26,475		$	52,456

d)  The distribution of income from operations by business segment was as follows:

	Three Months Ended					Six Months Ended
	June 30,		June 30,			June 30,			June 30,			June 30,			June 30,
	2011		2010			2011			2011			2011			2010
						Excluding Restructuring Charges			Restructuring Charges			Including Restructuring Charges
	(in thousands)					(in thousands)
Clinical research	$	14,939	$	26,811		$	33,616			(3,457	)	$	30,159		$	53,531
Central laboratory		567		(1,133	)		(2,139	)		(1,545	)		(3,684	)		(1,075	)
Total	$	15,506	$	25,678		$	31,477		$	(5,002	)	$	26,475		$	52,456

e) The distribution of property, plant and equipment, net, by geographical area was as follows:

	June 30,		December 31,
	2011		2010
	(in thousands)
Ireland	$	115,118	$	109,919
Rest of Europe		18,664		16,675
U.S.		32,328		33,855
Other		9,022		10,412
Total	$	175,132	$	170,861

f) The distribution of property, plant and equipment, net, by business segment was as follows:

	June 30,		December 31,
	2011		2010
	(in thousands)
Clinical research	$	154,252	$	149,755
Central laboratory		20,880		21,106
Total	$	175,132	$	170,861

g) The distribution of depreciation and amortization by geographical area was as follows:

	Three Months Ended				Six Months Ended
	June 30,		June 30,		June 30,		June 30,
	2011		2010		2011		2010
	(in thousands)				(in thousands)
Ireland	$	3,236	$	2,347	$	6,182	$	4,977
Rest of Europe		1,854		1,283		3,436		2,859
U.S.		3,125		3,647		6,468		7,215
Other		1,114		1,004		2,216		1,952
Total	$	9,329	$	8,281	$	18,302	$	17,003

h) The distribution of depreciation and amortization by business segment was as follows:

	Three Months Ended				Six Months Ended
	June 30,		June 30,		June 30,		June 30,
	2011		2010		2011		2010
	(in thousands)				(in thousands)
Clinical research	$	7,962	$	7,045	$	15,697	$	14,525
Central laboratory		1,367		1,236		2,605		2,478
Total	$	9,329	$	8,281	$	18,302	$	17,003

i) The distribution of total assets by geographical area was as follows:

	June 30,		December 31,
	2011		2010
	(in thousands)
Ireland	$	402,130	$	418,098
Rest of Europe		240,854		173,668
U.S.		338,662		329,971
Other		32,603		27,801
Total	$	1,014,249	$	949,538

j) The distribution of total assets by business segment was as follows:

	June 30,		December 31,
	2011		2010
	(in thousands)
Clinical research	$	952,179	$	889,534
Central laboratory		62,070		60,004
Total	$	1,014,249	$	949,538

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Goodwill (Tables)

6 Months Ended

Jun. 30, 2011

Goodwill

	June 30,		December 31,
	2011		2010
	(in thousands)
Opening balance	$	175,860	$	173,568
Current period acquisitions		39,718		3,505
Prior period acquisitions		-		2,539
Foreign exchange movement		4,033		(3,752	)
Closing balance	$	219,611	$	175,860

Oxford Outcomes Limited

Schedule of Assets Acquired and the Liabilities Assumed

The following table summarizes the fair values of the assets acquired and the liabilities assumed:

	January 14
	2011
	(in thousands)
Property, plant and equipment	$	490
Goodwill		39,718
Cash and cash equivalents		6,335
Other current assets		6,679
Current liabilities		(1,995	)
Purchase price	$	51,227

Timaq Medical Imaging

Schedule of Assets Acquired and the Liabilities Assumed

The following table summarizes the fair values of the assets acquired and the liabilities assumed:

	May 17
	2010
	(in thousands)
Property, plant and equipment	$	107
Goodwill		3,505
Intangible assets		770
Other current assets		160
Current liabilities		(719	)
Purchase price	$	3,823

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Restructuring charges (Tables)

6 Months Ended

Jun. 30, 2011

Restructuring Charges

Restructuring charges recognized during the six months ended June 30, 2011 comprise:

		Six Months Ended
		June 30,		June 30,
		2011		2010
		(in thousands)
Restructuring charges	$	5,002	$	-

Details of the movement in restructuring provisions recognised

Details of the movement in restructuring provisions recognised during the six months ended June 30, 2011 are as follows:

	Workforce			Office
	Reductions			Consolidations			Total
	(in thousands)
Initial provision recognised	$	3,956		$	1,046		$	5,002
Cash payments		(2,491	)		(95	)		(2,586	)
P,P&E write-off		-			(29	)		(29	)
Foreign exchange movement		(1	)		(8	)		(9	)
Closing provision	$	1,464		$	914		$	2,378

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Net income per ordinary share (Tables)

6 Months Ended

Jun. 30, 2011

Reconciliation of Number of Shares Used in the Computation of Basic and Diluted Net Income Per Ordinary Share

The reconciliation of the number of shares used in the computation of basic and diluted net income per ordinary share is as follows:

	Three Months Ended				Six Months Ended
	June 30,		June 30,		June 30,		June 30,
	2011		2010		2011		2010
Weighted average number of ordinary shares outstanding for basic net income per ordinary share		60,390,788		59,667,635		60,336,933		59,395,142
Effect of dilutive share options outstanding		724,208		1,100,739		719,299		1,162,545
Weighted average number of ordinary shares for diluted net income per ordinary share		61,114,996		60,768,374		61,056,232		60,557,687

XML



Stock Options (Tables)

6 Months Ended

Jun. 30, 2011

Summary of Stock Option Activity

The following table summarizes option activity for the six months ended June 30, 2011:

	Options Outstanding Number of Shares			Weighted Average Exercise Price		Weighted Average Fair Value		Weighted Average Remaining Contractual Life
Outstanding at December 31, 2010		4,798,677		$	21.71	$	8.47
Granted		799,449		$	20.25	$	8.52
Exercised		(185,260	)	$	12.73	$	5.46
Forfeited		(254,900	)	$	26.41	$	10.05
Outstanding at June 30, 2011		5,157,966		$	21.57	$	8.51		4.89
Exercisable at June 30, 2011		2,642,124		$	19.48	$	7.77		3.51

Summary of Movement in Non-Vested Share Options

The following table summarizes the movement in non-vested share options for the six months ended June 30, 2011:

	Options Outstanding Number of Shares			Weighted Average Exercise Price		Weighted Average Fair Value
Non vested outstanding at December 31, 2010		2,673,674		$	24.76	$	9.48
Granted		799,449		$	20.25	$	8.52
Vested		(718,445	)	$	20.15	$	7.61
Forfeited		(238,836	)	$	25.52	$	9.79
Non vested outstanding at June 30, 2011		2,515,842		$	23.77	$	9.29

Schedule of Weighted Average Fair Values and Assumptions Used

The weighted average fair values and assumptions used were as follows:

	Three Months Ended
	June 30,			June 30,
	2011			2010
Weighted average fair value	$	8.52		$	9.13
Assumptions:
Expected volatility		45	%		45	%
Dividend yield		0	%		0	%
Risk-free interest rate		2.3	%		1.8	%
Expected life	5 years			4.05 years

Summarizes the Movement in Non-vested Restricted Share Units

The following table summarizes the movement in non-vested restricted share units for the six months ended June 30, 2011:

	Number of Units			Weighted Average Fair Value
Non vested outstanding at December 31, 2010		1,256		$	41.95
Granted		230,000		$	21.26
Vested		(1,256	)	$	41.95
Forfeited		-			-
Non vested outstanding at June 30, 2011		230,000		$	21.26

Schedule of Non-cash stock compensation expense

Non-cash stock compensation expense for the six months ended June 30, 2011 has been allocated to direct costs and selling, general and administrative expenses as follows:

	Three Months Ended				Six Months Ended
	June 30,		June 30,		June 30,		June 30,
	2011		2010		2011		2010
	(In thousands)				(In thousands)
Direct costs	$	1,209	$	1,017	$	2,280	$	2,007
Selling, general and administrative	$	985	$	888	$	1,857	$	1,696
	$	2,194	$	1,905	$	4,137	$	3,703

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Segment Information (Tables)

6 Months Ended

Jun. 30, 2011

Distribution of Net Revenue by Geographical Area

a) The distribution of net revenue by geographical area was as follows:

	Three Months Ended				Six Months Ended
	June 30,		June 30,		June 30,		June 30,
	2011		2010		2011		2010
	(in thousands)				(in thousands)
Ireland	$	24,080	$	33,906	$	53,433	$	62,878
Rest of Europe		85,868		70,112		166,945		140,850
U.S.		93,826		96,876		186,390		194,331
Other		29,271		22,857		55,574		44,804
Total	$	233,045	$	223,751	$	462,342	$	442,863

    * All sales shown for Ireland are export sales.

Distribution of Net Revenue by Business Segment

b)  The distribution of net revenue by business segment was as follows:

	Three Months Ended				Six Months Ended
	June 30,		June 30,		June 30,		June 30,
	2011		2010		2011		2010
	(in thousands)				(in thousands)
Clinical research	$	216,163	$	208,114	$	429,007	$	411,010
Central laboratory		16,882		15,637		33,335		31,853
Total	$	233,045	$	223,751	$	462,342	$	442,863

Distribution of Income from Operations by Geographical Area

c)  The distribution of income from operations by geographical area was as follows:

	Three Months Ended					Six Months Ended
	June 30,			June 30,		June 30,			June 30,			June 30,			June 30,
	2011			2010		2011			2011			2011			2010
						Excluding Restructuring Charges			Restructuring Charges			Including Restructuring Charges
	(in thousands)					(in thousands)
Ireland	$	(4,386	)	$	13,526	$	(1,797	)		(85	)	$	(1,882	)	$	23,060
Rest of Europe		11,368			5,072		16,841			(1,803	)		15,038			12,931
U.S.		6,600			5,763		12,891			(3,114	)		9,777			13,432
Other		1,924			1,317		3,542			-			3,542			3,033
Total	$	15,506		$	25,678	$	31,477		$	(5,002	)	$	26,475		$	52,456

Distribution of income From Operations by Business Segment

d)  The distribution of income from operations by business segment was as follows:

	Three Months Ended					Six Months Ended
	June 30,		June 30,			June 30,			June 30,			June 30,			June 30,
	2011		2010			2011			2011			2011			2010
						Excluding Restructuring Charges			Restructuring Charges			Including Restructuring Charges
	(in thousands)					(in thousands)
Clinical research	$	14,939	$	26,811		$	33,616			(3,457	)	$	30,159		$	53,531
Central laboratory		567		(1,133	)		(2,139	)		(1,545	)		(3,684	)		(1,075	)
Total	$	15,506	$	25,678		$	31,477		$	(5,002	)	$	26,475		$	52,456

Distribution of Property, Plant and Equipment, Net, by Geographical Area

e) The distribution of property, plant and equipment, net, by geographical area was as follows:

	June 30,		December 31,
	2011		2010
	(in thousands)
Ireland	$	115,118	$	109,919
Rest of Europe		18,664		16,675
U.S.		32,328		33,855
Other		9,022		10,412
Total	$	175,132	$	170,861

Distribution of Property, Plant and Equipment, Net, by Business Segment

f) The distribution of property, plant and equipment, net, by business segment was as follows:

	June 30,		December 31,
	2011		2010
	(in thousands)
Clinical research	$	154,252	$	149,755
Central laboratory		20,880		21,106
Total	$	175,132	$	170,861

Distribution of Depreciation and Amortization by Geographical Area

g) The distribution of depreciation and amortization by geographical area was as follows:

	Three Months Ended				Six Months Ended
	June 30,		June 30,		June 30,		June 30,
	2011		2010		2011		2010
	(in thousands)				(in thousands)
Ireland	$	3,236	$	2,347	$	6,182	$	4,977
Rest of Europe		1,854		1,283		3,436		2,859
U.S.		3,125		3,647		6,468		7,215
Other		1,114		1,004		2,216		1,952
Total	$	9,329	$	8,281	$	18,302	$	17,003

Distribution of Depreciation and Amortization by Business Segment

h) The distribution of depreciation and amortization by business segment was as follows:

	Three Months Ended				Six Months Ended
	June 30,		June 30,		June 30,		June 30,
	2011		2010		2011		2010
	(in thousands)				(in thousands)
Clinical research	$	7,962	$	7,045	$	15,697	$	14,525
Central laboratory		1,367		1,236		2,605		2,478
Total	$	9,329	$	8,281	$	18,302	$	17,003

Distribution of Total Assets by Geographical Area

i) The distribution of total assets by geographical area was as follows:

	June 30,		December 31,
	2011		2010
	(in thousands)
Ireland	$	402,130	$	418,098
Rest of Europe		240,854		173,668
U.S.		338,662		329,971
Other		32,603		27,801
Total	$	1,014,249	$	949,538

Distribution of Total Assets by Business Segment

j) The distribution of total assets by business segment was as follows:

	June 30,		December 31,
	2011		2010
	(in thousands)
Clinical research	$	952,179	$	889,534
Central laboratory		62,070		60,004
Total	$	1,014,249	$	949,538

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Goodwill (Detail) (USD $) In Thousands	6 Months Ended	12 Months Ended
	Jun. 30, 2011	Dec. 31, 2010
Goodwill [Line Items]
Opening balance	$ 175,860	$ 173,568
Current period acquisitions	39,718	3,505
Prior period acquisitions		2,539
Foreign exchange movement	4,033	(3,752)
Closing balance	$ 219,611	$ 175,860

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Statement of Financial Position, Classified (USD $) In Thousands	Jun. 30, 2011	Dec. 31, 2010
Current Assets:
Cash and cash equivalents	$ 175,564	$ 255,706
Short term investments - available for sale	40,000
Accounts receivable	171,014	164,907
Unbilled revenue	143,323	101,431
Other receivables	17,643	12,451
Deferred tax asset	7,700	5,623
Prepayments and other current assets	22,573	20,592
Income taxes receivable	17,969	18,966
Total current assets	595,786	579,676
Other Assets:
Property, plant and equipment, net	175,132	170,861
Goodwill	219,611	175,860
Non-current other assets	4,538	4,353
Non-current income taxes receivable	475	482
Non-current deferred tax asset	11,477	10,028
Intangible assets	7,230	8,278
Total Assets	1,014,249	949,538
Current Liabilities:
Accounts payable	4,291	12,314
Payments on account	142,345	134,240
Other liabilities	122,007	100,182
Deferred tax liability	1,335	956
Income taxes payable	1,029	2,634
Total current liabilities	271,007	250,326
Other Liabilities:
Non-current other liabilities	4,468	3,676
Non-current government grants	1,500	1,470
Non-current income taxes payable	10,770	10,205
Non-current deferred tax liability	14,704	13,862
Shareholders' Equity:
Ordinary shares, par value 6 euro cents per share; 100,000,000 shares authorized, 60,436,120 shares issued and outstanding at June 30, 2011 and 60,247,092 shares issued and outstanding at December 31, 2010	5,079	5,063
Additional paid-in capital	203,658	196,960
Accumulated other comprehensive income	14,053	396
Retained earnings	489,010	467,580
Total Shareholders' Equity	711,800	669,999
Total Liabilities and Shareholders' Equity	$ 1,014,249	$ 949,538

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Goodwill - Additional Information (Detail) In Millions, unless otherwise specified															1 Months Ended
	Jun. 30, 2011 Oxford Outcomes Limited USD ($)	Jun. 30, 2011 Oxford Outcomes Limited GBP (£)	May 31, 2011 Oxford Outcomes Limited USD ($)	May 31, 2011 Oxford Outcomes Limited GBP (£)	Jan. 14, 2011 Oxford Outcomes Limited GBP (£)	Jan. 14, 2011 Oxford Outcomes Limited USD ($)	Jan. 14, 2011 Oxford Outcomes Limited Maximum GBP (£)	Jan. 14, 2011 Oxford Outcomes Limited Maximum USD ($)	Jun. 30, 2011 Oxford Outcomes Limited Maximum Options Held USD ($)	Jun. 30, 2011 Oxford Outcomes Limited Maximum Options Held GBP (£)	Jun. 30, 2011 Oxford Outcomes Limited Options Held GBP (£)	Jun. 30, 2011 Oxford Outcomes Limited Options Held USD ($)	May 17, 2011 Timaq Medical Imaging Maximum USD ($)	May 17, 2010 Timaq Medical Imaging Maximum CHF	Dec. 31, 2010 Timaq Medical Imaging USD ($)	Jun. 30, 2011 Timaq Medical Imaging CHF	Jun. 30, 2011 Timaq Medical Imaging USD ($)	May 17, 2011 Timaq Medical Imaging USD ($)	May 17, 2010 Timaq Medical Imaging CHF
Goodwill [Line Items]
Percentage of common stock acquired					80.00%	80.00%
Cash consideration					£ 17.8	$ 27.7					£ 3.8	$ 6.1						$ 1.2	1.3
Potential additional consideration							6.5	10.4	2.4	1.5			3.1	2.9
Payment to the former shareholders in respect of certain milestones															0.3
Accrual in respect performance milestones	10.4	6.5									3.8	6.1				2.6	2.9
Accrued consideration relating to the potential additional consideration payable											1.5	2.4
Additional amount Company paid on completion of review			$ 5.5	£ 3.3

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Summary of Fair Values of the Assets Acquired and the Liabilities Assumed Related to Acquisition of Oxford Outcomes (Detail) (Oxford Outcomes Limited, USD $) In Thousands	Jan. 14, 2011
Oxford Outcomes Limited
Business Acquisition [Line Items]
Property, plant and equipment	$ 490
Goodwill	39,718
Cash and cash equivalents	6,335
Other current assets	6,679
Current liabilities	(1,995)
Purchase price	$ 51,227

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Summary of Fair Values of the Assets Acquired and the Liabilities Assumed Related to Acquisition of Timaq Medical Imaging (Detail) (Timaq Medical Imaging, USD $) In Thousands	May 17, 2010
Timaq Medical Imaging
Business Acquisition [Line Items]
Property, plant and equipment	$ 107
Goodwill	3,505
Intangible assets	770
Other current assets	160
Current liabilities	(719)
Purchase price	$ 3,823

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Restructuring Charges (Detail) (USD $) In Thousands	6 Months Ended
	Jun. 30, 2011
Restructuring Cost and Reserve [Line Items]
Restructuring charges	$ 5,002

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Restructuring Charges - Additional Information (Detail) (USD $)	6 Months Ended
	Jun. 30, 2011
Restructuring Cost and Reserve [Line Items]
Restructuring charges	$ 5,002,000
Lease termination and exit costs	1,000,000
Workforce reductions	$ 4,000,000

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Details of the Movement in Restructuring Provisions Recognised (Detail) (USD $) In Thousands	6 Months Ended
	Jun. 30, 2011
Restructuring Cost and Reserve [Line Items]
Initial provision recognised	$ 5,002
Cash payments	(2,586)
P,P&E write-off	(29)
Foreign exchange movement	(9)
Closing provision	2,378
Workforce Reduction
Restructuring Cost and Reserve [Line Items]
Initial provision recognised	3,956
Cash payments	(2,491)
Foreign exchange movement	(1)
Closing provision	1,464
Office Consolidations
Restructuring Cost and Reserve [Line Items]
Initial provision recognised	1,046
Cash payments	(95)
P,P&E write-off	(29)
Foreign exchange movement	(8)
Closing provision	$ 914

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Income Tax - Additional Information (Detail) (USD $) In Millions	Jun. 30, 2011	Dec. 31, 2010
Deferred Tax Liability Not Recognized [Line Items]
Liability for unrecognized tax benefit	$ 10.3	$ 9.7
Items generating unrecognized tax benefits	8.5	8.1
Interest and related penalties	$ 1.8	$ 1.8

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Reconciliation of the Number of Shares Used in the Computation of Basic and Diluted Net Income Per Ordinary Share - Additional Information (Detail)	3 Months Ended		6 Months Ended
	Jun. 30, 2011	Jun. 30, 2010	Jun. 30, 2011	Jun. 30, 2010
Weighted average number of ordinary shares outstanding for basic net income per ordinary share	60,390,788	59,667,635	60,336,933	59,395,142
Effect of dilutive share options outstanding	724,208	1,100,739	719,299	1,162,545
Weighted average number of ordinary shares for diluted net income per ordinary share	61,114,996	60,768,374	61,056,232	60,557,687

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Stock Options - Additional Information (Detail) (USD $)	6 Months Ended						6 Months Ended		1 Months Ended		0 Months Ended	1 Months Ended			6 Months Ended
	Jun. 30, 2011 Year	Jun. 30, 2010	Jun. 30, 2010 Employee Stock Plan, 2008 Plan	Jun. 30, 2011 Employee Stock Plan, 2008 Plan Minimum	Jun. 30, 2010 Employee Stock Plan, 2008 Plan Individual Employee	Jul. 21, 2008 Restricted Stock Units 2008	Jun. 30, 2011 Employee Stock Plan, 2003 Plan	Jun. 30, 2011 Employee Stock Plan, 2003 Plan Individual Employee	Jun. 07, 2011 Restricted Stock Units (RSUs)	May 20, 2011 Restricted Stock Units (RSUs)	Mar. 03, 2011 Restricted Stock Units (RSUs)	Feb. 10, 2011 Restricted Stock Units (RSUs)	Aug. 16, 2010 Restricted Stock Units (RSUs)	Aug. 07, 2008 Restricted Stock Units (RSUs)	Jun. 30, 2011 Restricted Stock Units (RSUs)	Jun. 30, 2011 Minimum	Jun. 30, 2011 Maximum Year
Percentage of option price for fair value of ordinary share				100.00%
Ordinary shares which have been reserved for issuance			6,000,000		400,000	1,000,000	6,000,000	400,000
Maximum number of award as percentage of shares outstanding							10.00%
Awards granted to certain key employees	799,449								10,000		120,000	100,000		6,280	230,000
Vesting period	5 years								3 years	February 26, 2011	3 years	5 years	February 26, 2009
Market price of the Company's ordinary shares on date of award									$ 24.60		$ 20.28	$ 22.11		$ 41.95
Expiration period	8 years
Ordinary shares issued by the Company										3,768			2,512
Contractual term options outstanding	4.89																8
Option granted fair value	$ 7.15															$ 3.68	$ 13.93
Exercisable - number of shares	2,642,124
Exercisable - weighted average remaining contractual life	3.51
Exercisable - weighted average exercise price	$ 19.48
Fully vested total intrinsic value	$ 17,100,000
Intrinsic value of option exercised	2,000,000	14,900,000
Fair value of stock awards vested	100,000	100,000
Non-cash stock compensation expense not yet recognized	17,200,000
Weighted average period over which compensation expense is expected to be recognized	3.2
Tax benefit on exercise of options	$ 285,000	$ 1,000,000

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Summary of Stock Option Activity (Detail) (USD $)	6 Months Ended
	Jun. 30, 2011 Year	Jun. 30, 2010
Options Outstanding Number of Shares
Outstanding at beginning of period	4,798,677
Granted	799,449
Exercised	(185,260)
Forfeited	(254,900)
Outstanding at ending of period	5,157,966
Exercisable at ending of period	2,642,124
Weighted Average Exercise Price
Outstanding at beginning of period	$ 21.71
Granted	$ 20.25
Exercised	$ 12.73
Forfeited	$ 26.41
Outstanding at ending of period	$ 21.57
Exercisable at end of period	$ 19.48
Weighted Average Fair Value
Outstanding at beginning of period	$ 8.47
Granted	$ 8.52	$ 9.13
Exercised	$ 5.46
Forfeited	$ 10.05
Outstanding at end of period	$ 8.51
Exercisable at end of period	$ 7.77
Weighted Average Remaining Contractual Life
Outstanding Weighted Average Remaining Contractual Life	4.89
Exercisable Weighted Average Remaining Contractual Life	3.51

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Statement of Financial Position, Classified (Parenthetical)	Jun. 30, 2011 EUR (€)	Dec. 31, 2010 EUR (€)
Ordinary shares, par value	€ 0.06	€ 0.06
Ordinary shares, shares authorized	100,000,000	100,000,000
Ordinary shares, shares issued	60,436,120	60,247,092
Ordinary shares, shares outstanding	60,436,120	60,247,092

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Schedule of Movement in Non-Vested Share Options (Detail) (USD $)	6 Months Ended
	Jun. 30, 2011
Options Outstanding Number of Shares Exercise Price Non-vested
Non vested outstanding at beginning of period	2,673,674
Granted	799,449
Vested	(718,445)
Forfeited	(238,836)
Non vested outstanding at end of period	2,515,842
Weighted Average Exercise Price Non-vested
Non vested outstanding at beginning of period	$ 24.76
Granted	$ 20.25
Vested	$ 20.15
Forfeited	$ 25.52
Non vested outstanding at end of period	$ 23.77
Weighted Average Fair Value Non-vested
Non vested outstanding at beginning of period	$ 9.48
Granted	$ 8.52
Vested	$ 7.61
Forfeited	$ 9.79
Non vested outstanding at end of period	$ 9.29

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Schedule of Weighted Average Fair Values and Assumptions Used (Detail) (USD $)	6 Months Ended
	Jun. 30, 2011 Year	Jun. 30, 2010 Year
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Weighted average fair value	$ 8.52	$ 9.13
Assumptions:
Expected volatility	45.00%	45.00%
Dividend yield	0.00%	0.00%
Risk-free interest rate	2.30%	1.80%
Expected life	5.00	4.05

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Summarizes the Movement in Non-vested Restricted Share Units (Detail) (USD $)	1 Months Ended	0 Months Ended	1 Months Ended		6 Months Ended
	Jun. 07, 2011	Mar. 03, 2011	Feb. 10, 2011	Aug. 07, 2008	Jun. 30, 2011
Options Outstanding Number of Shares Exercise Price Non-vested
Non vested outstanding at beginning of period					2,673,674
Granted					799,449
Vested					(718,445)
Forfeited					238,836
Non vested outstanding at end of period					2,515,842
Weighted Average Fair Value Non-vested
Non vested outstanding at beginning of period					$ 9.48
Granted					$ 8.52
Vested					$ 7.61
Forfeited					$ 9.79
Non vested outstanding at end of period					$ 9.29
Restricted Stock Units (RSUs)
Options Outstanding Number of Shares Exercise Price Non-vested
Non vested outstanding at beginning of period					1,256
Granted	10,000	120,000	100,000	6,280	230,000
Vested					(1,256)
Forfeited
Non vested outstanding at end of period					230,000
Weighted Average Fair Value Non-vested
Non vested outstanding at beginning of period					$ 41.95
Granted					$ 21.26
Vested					$ 41.95
Forfeited
Non vested outstanding at end of period					$ 21.26

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Non-Cash Stock Compensation Expense (Detail) (USD $) In Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2011	Jun. 30, 2010	Jun. 30, 2011	Jun. 30, 2010
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share-based compensation expense	$ 2,194	$ 1,905	$ 4,137	$ 3,703
Cost of Sales
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share-based compensation expense	1,209	1,017	2,280	2,007
Selling, General and Administrative Expense
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share-based compensation expense	$ 985	$ 888	$ 1,857	$ 1,696

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Distribution of Net Revenue by Geographical Area (Detail) (USD $) In Thousands	3 Months Ended				6 Months Ended
	Jun. 30, 2011		Jun. 30, 2010		Jun. 30, 2011		Jun. 30, 2010
Segment Reporting Information [Line Items]
Net Revenue	$ 233,045		$ 223,751		$ 462,342		$ 442,863
IRELAND
Segment Reporting Information [Line Items]
Net Revenue	24,080	[1]	33,906	[1]	53,433	[1]	62,878	[1]
Rest of Europe
Segment Reporting Information [Line Items]
Net Revenue	85,868		70,112		166,945		140,850
UNITED STATES
Segment Reporting Information [Line Items]
Net Revenue	93,826		96,876		186,390		194,331
Other
Segment Reporting Information [Line Items]
Net Revenue	$ 29,271		$ 22,857		$ 55,574		$ 44,804

[1] All sales shown for Ireland are export sales.

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Distribution of Net Revenue by Business Segment (Detail) (USD $) In Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2011	Jun. 30, 2010	Jun. 30, 2011	Jun. 30, 2010
Segment Reporting Information [Line Items]
Net Revenue	$ 233,045	$ 223,751	$ 462,342	$ 442,863
Clinical Research
Segment Reporting Information [Line Items]
Net Revenue	216,163	208,114	429,007	411,010
Central Laboratory
Segment Reporting Information [Line Items]
Net Revenue	$ 16,882	$ 15,637	$ 33,335	$ 31,853

XML



Distribution of Income from Operations by Geographical Area (Detail) (USD $) In Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2011	Jun. 30, 2010	Jun. 30, 2011	Jun. 30, 2010
Segment Reporting Information [Line Items]
Income from Operations Excluding Restructuring Charges			$ 31,477
Restructuring Charges			(5,002)
Income from Operations	15,506	25,678	26,475	52,456
IRELAND
Segment Reporting Information [Line Items]
Income from Operations Excluding Restructuring Charges			(1,797)
Restructuring Charges			(85)
Income from Operations	(4,386)	13,526	(1,882)	23,060
Rest of Europe
Segment Reporting Information [Line Items]
Income from Operations Excluding Restructuring Charges			16,841
Restructuring Charges			(1,803)
Income from Operations	11,368	5,072	15,038	12,931
UNITED STATES
Segment Reporting Information [Line Items]
Income from Operations Excluding Restructuring Charges			12,891
Restructuring Charges			(3,114)
Income from Operations	6,600	5,763	9,777	13,432
Other
Segment Reporting Information [Line Items]
Income from Operations Excluding Restructuring Charges			3,542
Income from Operations	$ 1,924	$ 1,317	$ 3,542	$ 3,033

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Distribution of Income from Operations by Segment (Detail) (USD $) In Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2011	Jun. 30, 2010	Jun. 30, 2011	Jun. 30, 2010
Income from Operations Excluding Restructuring Charges			$ 31,477
Restructuring Charges			(5,002)
Income from Operations	15,506	25,678	26,475	52,456
Clinical Research
Income from Operations Excluding Restructuring Charges			33,616
Restructuring Charges			(3,457)
Income from Operations	14,939	26,811	30,159	53,531
Central Laboratory
Income from Operations Excluding Restructuring Charges			(2,139)
Restructuring Charges			(1,545)
Income from Operations	$ 567	$ (1,133)	$ (3,684)	$ (1,075)

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Distribution of Property, Plant and Equipment, Net, by Geographical Area (Detail) (USD $) In Thousands	Jun. 30, 2011	Dec. 31, 2010
Segment Reporting Information [Line Items]
Property, plant and equipment, net	$ 175,132	$ 170,861
IRELAND
Segment Reporting Information [Line Items]
Property, plant and equipment, net	115,118	109,919
Rest of Europe
Segment Reporting Information [Line Items]
Property, plant and equipment, net	18,664	16,675
UNITED STATES
Segment Reporting Information [Line Items]
Property, plant and equipment, net	32,328	33,855
Other
Segment Reporting Information [Line Items]
Property, plant and equipment, net	$ 9,022	$ 10,412

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Distribution of Property, Plant and Equipment, Net, by Business Segment (Detail) (USD $) In Thousands	Jun. 30, 2011	Dec. 31, 2010
Segment Reporting Information [Line Items]
Property, plant and equipment, net	$ 175,132	$ 170,861
Clinical Research
Segment Reporting Information [Line Items]
Property, plant and equipment, net	154,252	149,755
Central Laboratory
Segment Reporting Information [Line Items]
Property, plant and equipment, net	$ 20,880	$ 21,106

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Statement of Income (Excluding Gross Margin Alternative) (USD $) In Thousands, except Share data	3 Months Ended		6 Months Ended
	Jun. 30, 2011	Jun. 30, 2010	Jun. 30, 2011	Jun. 30, 2010
Revenue:
Gross revenue	$ 317,696	$ 313,087	$ 623,243	$ 622,638
Reimbursable expenses	(84,651)	(89,336)	(160,901)	(179,775)
Net revenue	233,045	223,751	462,342	442,863
Costs and expenses:
Direct costs	150,866	130,869	295,336	262,187
Selling, general and administrative expense	57,344	58,923	117,227	111,217
Depreciation and amortization	9,329	8,281	18,302	17,003
Restructuring charges			5,002
Total costs and expenses	217,539	198,073	435,867	390,407
Income from operations	15,506	25,678	26,475	52,456
Interest income	294	405	527	640
Interest expense	(188)	(344)	(355)	(771)
Income before provision for income taxes	15,612	25,739	26,647	52,325
Provision for income taxes	(2,530)	(2,866)	(5,217)	(7,253)
Net income	$ 13,082	$ 22,873	$ 21,430	$ 45,072
Net income per Ordinary Share:
Basic	$ 0.22	$ 0.38	$ 0.36	$ 0.76
Diluted	$ 0.21	$ 0.38	$ 0.35	$ 0.74
Weighted average number of Ordinary Shares outstanding:
Basic	60,390,788	59,667,635	60,336,933	59,395,142
Diluted	61,114,996	60,768,374	61,056,232	60,557,687

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Distribution of Depreciation and Amortization by Geographical Area (Detail) (USD $) In Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2011	Jun. 30, 2010	Jun. 30, 2011	Jun. 30, 2010
Segment Reporting Information [Line Items]
Depreciation and amortization	$ 9,329	$ 8,281	$ 18,302	$ 17,003
IRELAND
Segment Reporting Information [Line Items]
Depreciation and amortization	3,236	2,347	6,182	4,977
Rest of Europe
Segment Reporting Information [Line Items]
Depreciation and amortization	1,854	1,283	3,436	2,859
UNITED STATES
Segment Reporting Information [Line Items]
Depreciation and amortization	3,125	3,647	6,468	7,215
Other
Segment Reporting Information [Line Items]
Depreciation and amortization	$ 1,114	$ 1,004	$ 2,216	$ 1,952

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Distribution of Depreciation and Amortization by Business Segment (Detail) (USD $) In Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2011	Jun. 30, 2010	Jun. 30, 2011	Jun. 30, 2010
Segment Reporting Information [Line Items]
Depreciation and amortization	$ 9,329	$ 8,281	$ 18,302	$ 17,003
Clinical Research
Segment Reporting Information [Line Items]
Depreciation and amortization	7,962	7,045	15,697	14,525
Central Laboratory
Segment Reporting Information [Line Items]
Depreciation and amortization	$ 1,367	$ 1,236	$ 2,605	$ 2,478

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Distribution of Total Assets by Geographical Area (Detail) (USD $) In Thousands	Jun. 30, 2011	Dec. 31, 2010
Segment Reporting Information [Line Items]
Assets	$ 1,014,249	$ 949,538
IRELAND
Segment Reporting Information [Line Items]
Assets	402,130	418,098
Rest of Europe
Segment Reporting Information [Line Items]
Assets	240,854	173,668
UNITED STATES
Segment Reporting Information [Line Items]
Assets	338,662	329,971
Other
Segment Reporting Information [Line Items]
Assets	$ 32,603	$ 27,801

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Distribution of Total Assets by Business Segment (Detail) (USD $) In Thousands	Jun. 30, 2011	Dec. 31, 2010
Segment Reporting Information [Line Items]
Assets	$ 1,014,249	$ 949,538
Clinical Research
Segment Reporting Information [Line Items]
Assets	952,179	889,534
Central Laboratory
Segment Reporting Information [Line Items]
Assets	$ 62,070	$ 60,004

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Statement of Cash Flows (USD $) In Thousands	6 Months Ended
	Jun. 30, 2011	Jun. 30, 2010
Cash flows from operating activities:
Net income	$ 21,430	$ 45,072
Adjustments to reconcile net income to net cash provided by operating activities:
Loss on disposal of property, plant and equipment	13	115
Depreciation and amortization	18,302	17,003
Amortization of grants	(59)	(77)
Share compensation expense	4,137	3,703
Deferred taxes	(2,296)	(1,451)
Changes in assets and liabilities:
Decrease in accounts receivable	3,949	19,195
(Increase)/decrease in unbilled revenue	(42,576)	12,398
Increase in other receivables	(4,831)	(243)
Increase in prepayments and other current assets	(1,188)	(3,662)
Increase in other non current assets	(185)	(626)
Decrease in payments on account	(316)	(20,784)
Increase/(decrease) in other current liabilities	1,537	(8,527)
(Decrease)/increase in other non current liabilities	(191)	472
(Increase)/decrease in income taxes receivable	314	(6,661)
Decrease in accounts payable	(9,699)	(4,107)
Net cash (used in)/provided by operating activities	(11,659)	51,820
Cash flows from investing activities:
Purchase of property, plant and equipment	(13,097)	(16,969)
Purchase of subsidiary undertakings	(33,227)	(1,161)
Cash acquired with subsidiary undertakings	6,335
Purchase of short term investments	(40,000)	(30,260)
Sale of short term investments		79,487
Net cash (used in)/provided by investing activities	(79,989)	31,097
Cash flows from financing activities:
Proceeds from exercise of share options	2,358	8,996
Share issuance costs	(66)	(28)
Tax benefit from the exercise of share options	285	2,179
Repayment of other liabilities		(160)
Net cash provided by financing activities	2,577	10,987
Effect of exchange rate movements on cash	8,929	(17,943)
Net (decrease)/increase in cash and cash equivalents	(80,142)	75,961
Cash and cash equivalents at beginning of period	255,706	144,801
Cash and cash equivalents at end of period	$ 175,564	$ 220,762

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Statement Of Shareholders Equity And Other Comprehensive Income (USD $) In Thousands, except Share data	Total	Ordinary shares	Additional Paid-in Capital	Accumulated Other Comprehensive Income	Retained Earnings
Beginning Balance at Dec. 31, 2010	$ 669,999	$ 5,063	$ 196,960	$ 396	$ 467,580
Beginning Balance (in shares) at Dec. 31, 2010		60,247,092
Comprehensive Income:
Net income	21,430				21,430
Currency translation adjustment	15,824			15,824
Currency impact of long term funding	(1,921)			(1,921)
Tax on currency impact of long term funding	(246)			(246)
Total comprehensive income	35,087
Exercise of share options (in shares)	185,260	185,260
Exercise of share options	2,358	16	2,342
Issue of ordinary shares		3,768
Share issuance costs	(66)		(66)
Non-cash stock compensation expense	4,137		4,137
Tax benefit on exercise of options	285		285
Ending Balance at Jun. 30, 2011	$ 711,800	$ 5,079	$ 203,658	$ 14,053	$ 489,010
Ending Balance (in shares) at Jun. 30, 2011		60,436,120

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Basis of Presentation

6 Months Ended

Jun. 30, 2011

Basis of Presentation

1. Basis of Presentation

These condensed consolidated financial statements, which have been prepared in accordance with United States generally accepted accounting principles (“US GAAP”), have not been audited. The condensed consolidated financial statements reflect all adjustments, which are, in the opinion of management, necessary to present a fair statement of the operating results and financial position for the periods presented. The preparation of the condensed consolidated financial statements in conformity with US GAAP requires management to make estimates and assumptions that affect reported amounts and disclosures in the condensed consolidated financial statements. Actual results could differ from those estimates.

The condensed consolidated financial statements should be read in conjunction with the accounting policies and notes to the consolidated financial statements included in ICON’s Form 20-F for the year ended December 31, 2010. Operating results for the six months ended June 30, 2011 are not necessarily indicative of the results that may be expected for the fiscal period ending December 31, 2011.

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Goodwill

6 Months Ended

Jun. 30, 2011

Goodwill

2. Goodwill

	June 30,		December 31,
	2011		2010
	(in thousands)
Opening balance	$	175,860	$	173,568
Current period acquisitions		39,718		3,505
Prior period acquisitions		-		2,539
Foreign exchange movement		4,033		(3,752	)
Closing balance	$	219,611	$	175,860

The goodwill balance relates entirely to the clinical research segment.

Acquisition of Oxford Outcomes

On January 14, 2011 the Company acquired approximately 80% of the common stock of Oxford Outcomes Limited, a leading international health outcomes consultancy business, headquartered in Oxford, United Kingdom, and with offices in the USA and Canada, for an initial cash consideration of £17.8 million ($27.7 million).  Oxford Outcomes provides specialist services in the areas of patient reported outcomes (PRO), health economics, epidemiology and translation and linguistic validation.  Further consideration of up to £6.5 million ($10.4 million) may become payable during the period to March 31, 2012 if certain performance milestones are achieved.  The Company has accrued £6.5 million ($10.4 million) in respect of these milestones at June 30, 2011.  In addition, the acquisition agreement also provided for certain working capital targets to be achieved by Oxford Outcomes Limited on completion.  In May 2011 the Company paid an additional £3.3 million ($5.5 million) on completion of this review.

The Company also holds an option to acquire the remaining common stock of Oxford Outcomes Limited during the year ended December 31, 2011 for cash consideration of £3.8 million ($6.1 million).  Further consideration of up to £1.5 million ($2.4 million) relating to this remaining common stock of Oxford Outcomes may become payable during the period to March 31, 2012 if certain performance milestones are achieved.  £3.8 million ($6.1 million) has been accrued at June 30, 2011 in respect of additional consideration payable in respect of this option and a further £1.5 million ($2.4 million) has been accrued at June 30, 2011 relating to the potential additional consideration payable in respect of the performance milestones.

The acquisition of Oxford Outcomes has been accounted for as a business combination in accordance with FASB ASC 805 Business Combinations. The following table summarizes the fair values of the assets acquired and the liabilities assumed:

	January 14
	2011
	(in thousands)
Property, plant and equipment	$	490
Goodwill		39,718
Cash and cash equivalents		6,335
Other current assets		6,679
Current liabilities		(1,995	)
Purchase price	$	51,227

Goodwill represents the acquisition of an established workforce with experience in the areas of patient reported outcomes (PRO), health economics, epidemiology and translation and linguistic validation.

Prior Period Acquisitions - Acquisition of Timaq Medical Imaging

On May 17, 2010 the Company acquired Timaq Medical Imaging (“Timaq”), a European provider of advanced imaging services to the pharmaceutical and biotechnology industry, located in Zurich, Switzerland for an initial cash consideration of CHF 1.3 million ($1.2 million).  Certain performance milestones were built into the acquisition agreement requiring potential additional consideration of up to CHF 2.9 million ($3.1 million) if these milestones are achieved during the years ended December 31, 2010 to December 31, 2013. On December 31, 2010 CHF 0.3 million ($0.3 million) was paid to the former shareholders in respect of certain milestones for the year ended December 31, 2010.  CHF 2.6 million ($2.9 million) has been accrued in relation to the remaining milestones at June 30, 2011.

The acquisition of Timaq has been accounted for as a business combination in accordance with FASB ASC 805 Business Combinations. The following table summarizes the fair values of the assets acquired and the liabilities assumed:

	May 17
	2010
	(in thousands)
Property, plant and equipment	$	107
Goodwill		3,505
Intangible assets		770
Other current assets		160
Current liabilities		(719	)
Purchase price	$	3,823

Goodwill represents the acquisition of an established workforce with experience in the provision of advanced imaging services to pharmaceutical and biotechnology customers in the European market.

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Restructuring charges

6 Months Ended

Jun. 30, 2011

Restructuring charges

3. Restructuring charges

Restructuring charges recognized during the six months ended June 30, 2011 comprise:

		Six Months Ended
		June 30,		June 30,
		2011		2010
		(in thousands)
Restructuring charges	$	5,002	$	-

During the six months ended June 30, 2011 the Company commenced a review of its operations to improve resource utilization within the business and better align resources to current and future growth opportunities of the business.  This review resulted in the adoption of a restructuring plan, the closure of the Company’s facility in Edinburgh, United Kingdom and resource rationalizations in certain of the more mature markets in which it operates.  A restructuring charge of $5.0 million was recognized during the six months ended June 30, 2011, $1.0 million in respect of lease termination and exit costs associated with the closure of the Edinburgh facility and $4.0 million in respect of workforce reductions.

Details of the movement in restructuring provisions recognised during the six months ended June 30, 2011 are as follows:

	Workforce			Office
	Reductions			Consolidations			Total
	(in thousands)
Initial provision recognised	$	3,956		$	1,046		$	5,002
Cash payments		(2,491	)		(95	)		(2,586	)
P,P&E write-off		-			(29	)		(29	)
Foreign exchange movement		(1	)		(8	)		(9	)
Closing provision	$	1,464		$	914		$	2,378