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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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MIC-Info: RSA-MD5,RSA,
 JpzBR3CT3pivqKR0YdkgLjMCChXXW2M3+opjeMx/G33N03RbK9t4afGMqaYaBZaw
 DbpuIH4HJ9pm+FqxEhLZUg==

<SEC-DOCUMENT>9999999995-10-000461.txt : 20100210
<SEC-HEADER>9999999995-10-000461.hdr.sgml : 20100210
<ACCEPTANCE-DATETIME>20100210001512
ACCESSION NUMBER:		9999999995-10-000461
CONFORMED SUBMISSION TYPE:	EFFECT
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20100209
DATE AS OF CHANGE:		20100210
EFFECTIVENESS DATE:		20100209

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			GENEREX BIOTECHNOLOGY CORP
		CENTRAL INDEX KEY:			0001059784
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				820490211
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			0731

	FILING VALUES:
		FORM TYPE:		EFFECT
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-164591
		FILM NUMBER:		10586110

	BUSINESS ADDRESS:	
		STREET 1:		33 HARBOUR SQ
		STREET 2:		STE 202
		CITY:			TORONTO ONTARIO CANADA
		STATE:			A1
		ZIP:			M5J 2G2
		BUSINESS PHONE:		4163642551

	MAIL ADDRESS:	
		STREET 1:		33 HARBOUR SQ
		STREET 2:		STE 202
		CITY:			TORONTO ONTARIO CA
		STATE:			A1
		ZIP:			M5J 2G2
</SEC-HEADER>
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<TYPE>EFFECT
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
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    <schemaVersion>X0101</schemaVersion>

    <submissionType>EFFECT</submissionType>

    <act>33</act>

    <testOrLive>LIVE</testOrLive>

    <effectiveData>
        <finalEffectivenessDispDate>2010-02-09</finalEffectivenessDispDate>
        <finalEffectivenessDispTime>09:00:00</finalEffectivenessDispTime>
        <form>S-3</form>
        <filer>
            <cik>0001059784</cik>
            <entityName>GENEREX BIOTECHNOLOGY CORP</entityName>
            <fileNumber>333-164591</fileNumber>
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