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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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<SEC-DOCUMENT>0000910680-07-000453.txt : 20070518
<SEC-HEADER>0000910680-07-000453.hdr.sgml : 20070518
<ACCEPTANCE-DATETIME>20070518163412
ACCESSION NUMBER:		0000910680-07-000453
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20070516
FILED AS OF DATE:		20070518
DATE AS OF CHANGE:		20070518

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Biodel Inc
		CENTRAL INDEX KEY:			0001322505
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000

	BUSINESS ADDRESS:	
		STREET 1:		6 CHRISTOPHER COLUMBUS AVE
		CITY:			DANBURY
		STATE:			CT
		ZIP:			06810
		BUSINESS PHONE:		203-798-3603

	MAIL ADDRESS:	
		STREET 1:		6 CHRISTOPHER COLUMBUS AVE
		CITY:			DANBURY
		STATE:			CT
		ZIP:			06810

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			ORBIMED ADVISORS LLC
		CENTRAL INDEX KEY:			0001055951
		STATE OF INCORPORATION:			DE

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-33451
		FILM NUMBER:		07865193

	BUSINESS ADDRESS:	
		STREET 1:		767 3RD AVENUE
		STREET 2:		30TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10017
		BUSINESS PHONE:		2126845700

	MAIL ADDRESS:	
		STREET 1:		767 3RD AVENUE
		STREET 2:		30TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10017
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>f4052007orbimedadvisors_ex.xml
<DESCRIPTION>FORM 4
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2007-05-16</periodOfReport>

    <notSubjectToSection16>1</notSubjectToSection16>

    <issuer>
        <issuerCik>0001322505</issuerCik>
        <issuerName>Biodel Inc</issuerName>
        <issuerTradingSymbol>BIOD</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001055951</rptOwnerCik>
            <rptOwnerName>ORBIMED ADVISORS LLC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>767 THIRD AVENUE</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10017</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2007-05-16</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>C</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>1258756</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>1966892</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See footnote</value>
                    <footnoteId id="F1"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Series B Convertible Preferred Stock</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <footnoteId id="F2"/>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2007-05-16</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>C</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>1258756</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F2"/>
            </exerciseDate>
            <expirationDate>
                <footnoteId id="F2"/>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>1258756</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>0</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See footnote</value>
                    <footnoteId id="F3"/>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeTransaction>
        <derivativeHolding>
            <securityTitle>
                <value>Director's Stock Option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>5.65</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F4"/>
            </exerciseDate>
            <expirationDate>
                <value>2014-07-10</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>17713</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>17713</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                    <footnoteId id="F5"/>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See footnote</value>
                    <footnoteId id="F6"/>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Director's Stock Option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>12.63</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F7"/>
            </exerciseDate>
            <expirationDate>
                <value>2014-11-30</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>2601</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>2601</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                    <footnoteId id="F8"/>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See footnote</value>
                    <footnoteId id="F6"/>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Director Stock Option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>15.00</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <value>2007-05-10</value>
            </exerciseDate>
            <expirationDate>
                <value>2017-05-09</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>25000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>25000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                    <footnoteId id="F9"/>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See footnote</value>
                    <footnoteId id="F6"/>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">The amount shown represents (i) 1,312,692 shares of Common Stock held directly by Caduceus Private Investments II LP, (ii)
 491,506 shares of Common Stock held by Caduceus Private Investments II (QP), LP, and (iii) 162,694 shares of Common Stock
 held  directly by UBS Juniper Crossover Fund, L.L.C., affiliates of the Reporting Person.  The Reporting Person disclaims
 beneficial ownership of the shares except to the extent of its pecuniary interest therein.</footnote>
        <footnote id="F2">The Series B Convertible Preferred Stock had no expiration date.  It was immediately exercisable and was converted into
 Common Stock of the Issuer on a one for one basis upon the close of the Issuer's initial public offering.</footnote>
        <footnote id="F3">The amount shown represents (i) 840,081 shares of Series B Convertible Preferred Stock held directly by Caduceus Private
 Investments II LP, (ii) 314,543  shares of our Series B Convertible Preferred Stock held directly by Caduceus Private
 Investments II (QP), LP, and (iii) 104,132 shares of Series B Convertible Preferred Stock held directly by UBS Juniper
 Crossover Fund, L.L.C., affiliates of the Reporting Person. The Reporting Person disclaims beneficial ownership of the
 shares except to the extent of its pecuniary interest therein.</footnote>
        <footnote id="F4">This option is exercisable in two equal installments on July 11, 2007 and July 11, 2008.</footnote>
        <footnote id="F5">The amount shown represents (i) options to purchase 11,822 shares of common stock, held directly by Caduceus Private
 Investments II LP, (ii) options to purchase 4,426 shares of common stock, held directly by Caduceus Private Investments II
 (QP), LP and  (iii) options to purchase 1,465 shares of common stock, held directly by UBS Juniper Crossover Fund, LLC.</footnote>
        <footnote id="F6">The options were granted to Samuel Wertheimer, a director of the Issuer.  Mr. Wertheimer is a principal of the Reporting
 Person.  Mr. Wertheimer is obligated to transfer any shares issued under the options to the Reporting Person.</footnote>
        <footnote id="F7">The option is exercisable in two equal installments on December 1, 2007 and December 1, 2008.</footnote>
        <footnote id="F8">The amount shown represents (i) options to purchase 1,736 shares of common stock, held directly by Caduceus Private
 Investments II LP, (ii) options to purchase 650 shares of common stock, held directly by Caduceus Private Investments II
 (QP), LP and  (iii) options to purchase 215 shares of common stock, held directly by UBS Juniper Crossover Fund, LLC.</footnote>
        <footnote id="F9">The amount shown represents (i) options to purchase 16,685 shares of common stock, held directly by Caduceus Private
 Investments II LP, (ii) options to purchase 6,247 shares of common stock, held directly by Caduceus Private Investments II
 (QP), LP and  (iii) options to purchase 2,068 shares of common stock, held directly by UBS Juniper Crossover Fund, LLC.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Samuel P. Wertheimer</signatureName>
        <signatureDate>2007-05-18</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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