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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 WTkDA8R5+f4qbl8kIFnG1ypNtGHLRnE9lJp9i7cbzK9TrpIzhr5jIyxMxltMO3QF
 PjK00a7BuJXFBKpSl5qz5w==

<SEC-DOCUMENT>0001354488-11-000073.txt : 20110105
<SEC-HEADER>0001354488-11-000073.hdr.sgml : 20110105
<ACCEPTANCE-DATETIME>20110105171932
ACCESSION NUMBER:		0001354488-11-000073
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20110103
FILED AS OF DATE:		20110105
DATE AS OF CHANGE:		20110105

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			LEONE JOSEPH M
		CENTRAL INDEX KEY:			0001176381

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-29819
		FILM NUMBER:		11511738

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Alliqua, Inc.
		CENTRAL INDEX KEY:			0001054274
		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
		IRS NUMBER:				582349413
		STATE OF INCORPORATION:			FL
		FISCAL YEAR END:			1220

	BUSINESS ADDRESS:	
		STREET 1:		850 THIRD AVENUE
		STREET 2:		SUITE 1801
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
		BUSINESS PHONE:		800-518-4879

	MAIL ADDRESS:	
		STREET 1:		850 THIRD AVENUE
		STREET 2:		SUITE 1801
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	HEPALIFE TECHNOLOGIES INC
		DATE OF NAME CHANGE:	20030529

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ZETA CORP
		DATE OF NAME CHANGE:	20030219

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ZETA CORP /CA
		DATE OF NAME CHANGE:	20000303
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>issuerdirect_section16.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2011-01-03</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001054274</issuerCik>
        <issuerName>Alliqua, Inc.</issuerName>
        <issuerTradingSymbol>ALQA</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001176381</rptOwnerCik>
            <rptOwnerName>LEONE JOSEPH M</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>850 THIRD AVENUE</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 1801</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10022</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Stock Option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.135</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2011-01-03</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>250000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2011-01-03</value>
            </exerciseDate>
            <expirationDate>
                <value>2021-01-03</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>250000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>250000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">Represents stock options granted to and accepted by the reporting person on January 3, 2011 pursuant to the Alliqua, Inc. 2001 Incentive Stock Plan.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Joseph Leone</signatureName>
        <signatureDate>2011-01-05</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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