-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 ByEfGOkCNHnCHhjja9R/dru3T9EPTE0j7Pr8HDg5evvYtBCLWNycaAJIWbTxjiPs
 8sGNpulyrRvOjjTYPY4FJA==

<SEC-DOCUMENT>0001354488-11-000068.txt : 20110105
<SEC-HEADER>0001354488-11-000068.hdr.sgml : 20110105
<ACCEPTANCE-DATETIME>20110105171037
ACCESSION NUMBER:		0001354488-11-000068
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20110103
FILED AS OF DATE:		20110105
DATE AS OF CHANGE:		20110105

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			LEONE JOSEPH M
		CENTRAL INDEX KEY:			0001176381

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-29819
		FILM NUMBER:		11511638

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Alliqua, Inc.
		CENTRAL INDEX KEY:			0001054274
		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
		IRS NUMBER:				582349413
		STATE OF INCORPORATION:			FL
		FISCAL YEAR END:			1220

	BUSINESS ADDRESS:	
		STREET 1:		850 THIRD AVENUE
		STREET 2:		SUITE 1801
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
		BUSINESS PHONE:		800-518-4879

	MAIL ADDRESS:	
		STREET 1:		850 THIRD AVENUE
		STREET 2:		SUITE 1801
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	HEPALIFE TECHNOLOGIES INC
		DATE OF NAME CHANGE:	20030529

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ZETA CORP
		DATE OF NAME CHANGE:	20030219

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ZETA CORP /CA
		DATE OF NAME CHANGE:	20000303
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>issuerdirect_section16.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0203</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2011-01-03</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001054274</issuerCik>
        <issuerName>Alliqua, Inc.</issuerName>
        <issuerTradingSymbol>ALQA</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001176381</rptOwnerCik>
            <rptOwnerName>LEONE JOSEPH M</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>850 THIRD AVENUE</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 1801</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10022</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>No securities beneficially owned</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>0</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes></footnotes>

    <ownerSignature>
        <signatureName>/s/ Joseph Leone</signatureName>
        <signatureDate>2011-01-05</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----