-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 NMFRnm41UrWTCPmCUYOHiVoZvWc73Q6XWbw/TMhczWDUpWUG1kIOdGDn5xvBRIjW
 lH6mF5WTt6NK/pHguStU4A==

<SEC-DOCUMENT>0001354488-11-000026.txt : 20110104
<SEC-HEADER>0001354488-11-000026.hdr.sgml : 20110104
<ACCEPTANCE-DATETIME>20110104162510
ACCESSION NUMBER:		0001354488-11-000026
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20101231
FILED AS OF DATE:		20110104
DATE AS OF CHANGE:		20110104

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			BERGER STEVEN C
		CENTRAL INDEX KEY:			0001287524

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-29819
		FILM NUMBER:		11506156

	MAIL ADDRESS:	
		STREET 1:		44 HEATHER HILL LANE
		CITY:			WOODCLIFF LAKE
		STATE:			NJ
		ZIP:			07677

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Alliqua, Inc.
		CENTRAL INDEX KEY:			0001054274
		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
		IRS NUMBER:				582349413
		STATE OF INCORPORATION:			FL
		FISCAL YEAR END:			1220

	BUSINESS ADDRESS:	
		STREET 1:		850 THIRD AVENUE
		STREET 2:		SUITE 1801
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
		BUSINESS PHONE:		800-518-4879

	MAIL ADDRESS:	
		STREET 1:		850 THIRD AVENUE
		STREET 2:		SUITE 1801
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	HEPALIFE TECHNOLOGIES INC
		DATE OF NAME CHANGE:	20030529

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ZETA CORP
		DATE OF NAME CHANGE:	20030219

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ZETA CORP /CA
		DATE OF NAME CHANGE:	20000303
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>issuerdirect_section16.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2010-12-31</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001054274</issuerCik>
        <issuerName>Alliqua, Inc.</issuerName>
        <issuerTradingSymbol>HPLF.OB</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001287524</rptOwnerCik>
            <rptOwnerName>BERGER STEVEN C</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>850 THIRD AVENUE</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 1801</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10022</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isOfficer>1</isOfficer>
            <officerTitle>CFO, Treasurer and Secretary</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Stock Option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.145</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2010-12-31</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>1000000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2015-12-09</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>1000000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>1000000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">Represents stock options granted to Steven C. Berger pursuant to the Alliqua, Inc. (the &quot;Company&quot;) 2001 Incentive Stock Plan on December 9, 2010 and accepted by Mr. Berger on December 31, 2010. These shares vest as follows: (i) 500,000 of the options granted vested immediately, (ii) 250,000 of the options vested on January 3, 2011 upon the creation of a Board of Directors of the Company that fully complied with the Corporate Governance Requirements set forth in Sections 801-809 of the NYSE Amex Rules, and (iii) 250,000 of the options shall vest only upon the filing of the Company's Annual Report on Form 10-K with the Securities and Exchange Commission for the fiscal year ending December 31, 2010 without any material weaknesses in the Company's financial reporting under the Sarbanes-Oxley Act of 2002.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Steven C. Berger</signatureName>
        <signatureDate>2011-01-04</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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