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Note 11 - Stock-based Compensation Stock - Stock Option Activity (Details) - USD ($)
$ / shares in Units, $ in Thousands
6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
Balance, number of shares (in shares) 349,374  
Balance, weighted average exercise price (in dollars per share) $ 51.15  
Granted, number of shares (in shares) 207,284 0
Granted, weighted average exercise price (in dollars per share) $ 11.23  
Expired, shares (in shares) (23,354)  
Expired, weighted average exercise price per share (in dollars per share) $ 114.18  
Outstanding, shares (in shares) 533,304  
Outstanding, weighted average exercise price per share (in dollars per share) $ 32.87  
Outstanding, weighted average remaining contractual term (Year) 8 years 4 months 24 days  
Outstanding, aggregate intrinsic value $ 0  
Exercisable, shares (in shares) 228,508  
Exercisable, weighted average exercise price per share (in dollars per share) $ 64.13  
Exercisable, weighted average remaining contractual term (Year) 6 years 8 months 12 days  
Exercisable, aggregate intrinsic value $ 0