Note 4 - Significant Agreements and Contracts (Details Textual) $ in Millions	1 Months Ended		3 Months Ended			12 Months Ended
	Feb. 29, 2024 USN ($)	Aug. 31, 2014 USD ($)	Jun. 30, 2024	Mar. 31, 2024 USD ($)	Mar. 31, 2023 USD ($)	Dec. 31, 2025 USD ($)	Dec. 31, 2024 USD ($)	Jan. 31, 2023 USD ($)	Jan. 01, 2023 USN ($)
Research and Development Expense				$ 2,814,258	$ 1,833,274
Revenues				2,347,250	1,407,868
Vertex Option and License Agreement [Member]
Research and Development Expense		$ 100,000
Contractual Obligation				117,000,000
Payments for License Agreement		$ 100,000
National Institute of Aging Grant [Member]
Government Assistance, Asset								$ 21,000,000	$ 21.0
Government Assistance, Income, Increase (Decrease)	$ 7.3			6,700,000
Revenues				2,300,000	$ 1,400,000
Proceeds From Grants				10,100,000
Grant Funding Remaining				$ 10,900,000
Grant Amount, Received, Parentage	90.00%
National Institute of Aging Grant [Member] | Forecast [Member]
Government Assistance, Income, Increase (Decrease)						$ 6,200,000	$ 8,100,000
Grant Amount, Received, Parentage			10.00%