Note 5 - Significant Agreements and Contracts (Details Textual) - USD ($)	1 Months Ended	3 Months Ended		9 Months Ended		12 Months Ended
	Aug. 31, 2014	Sep. 30, 2023	Sep. 30, 2022	Sep. 30, 2023	Sep. 30, 2022	Dec. 31, 2025	Dec. 31, 2024	Dec. 31, 2023	Jan. 31, 2023	Dec. 31, 2022
Research and Development Expense		$ 1,791,487	$ 330,543	$ 5,583,149	$ 955,784
Government Assistance, Amount, Cumulative									$ 21,000,000.0
Revenues		1,526,482	$ 0	4,654,294	$ 0
Deferred Revenue, Current		547,051		547,051						$ 0
Vertex Option and License Agreement [Member]
Research and Development Expense	$ 100,000
Contractual Obligation		117,000,000.0		117,000,000.0
Payments for License Agreement	$ 100,000
National Institute of Aging Grant [Member]
Government Assistance, Amount, Cumulative									$ 21,000,000.0
Revenues		1,600,000		4,700,000
Proceeds From Grants				5,200,000
Grant Funding Remaining		15,800,000		15,800,000
Deferred Revenue, Current		$ 500,000		$ 500,000
National Institute of Aging Grant [Member] | Forecast [Member]
Government Assistance, Amount						$ 6,200,000	$ 8,100,000	$ 6,700,000