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Note 10 - Income Taxes (Tables)
12 Months Ended
Dec. 31, 2022
Notes Tables  
Schedule of Components of Income Tax Expense (Benefit) [Table Text Block]
   

December 31, 2022

   

December 31, 2021

 

Federal

  $     $ (362,150 )

State

          (81,743 )

Total

          (443,893 )
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]

Deferred tax assets

 

December 31, 2022

   

December 31, 2021

 

Net operating loss carryforwards

  $ 8,650,404     $ 6,033,726  

Stock option compensation

    1,754,906       1,641,354  

Orphan Drug credits

    1,306,682       647,937  

Capitalized start-up costs and other

    12,788,834       12,403,925  

Valuation allowance

    (24,471,392 )     (20,726,942 )

Deferred tax assets

  $     $  
Summary of Operating Loss Carryforwards [Table Text Block]

Combined NOL Carryforwards:

 

December 31, 2022

   

December 31, 2021

 

Federal

  $ 34,116,553     $ 23,442,045  

State

    30,727,733       23,436,624  
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]

Rate reconciliation:

 

December 31, 2022

   

December 31, 2021

 

Federal tax benefit at statutory rate

    (21.0 )%     (21.0 )%

State tax, net of Federal benefit

    (3.9 )%     (4.7 )%

Orphan drug credit

    (4.5 )%     (0.4 )%

Change in valuation allowance

    29.0 %     24.3 %

Stock compensation

    0.4 %     %

Other

    %     %

Total provision

    %     (1.8 )%